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    Mesylate salt of an IKK inhibitor
    1.
    发明申请
    Mesylate salt of an IKK inhibitor 审中-公开
    IKK抑制剂的甲磺酸盐

    公开(公告)号：US20090137579A1

    公开(公告)日：2009-05-28

    申请号：US12288596

    申请日：2008-10-22

    申请人： Frederick A. Hicks ,  Martin Ian Cooper ,  Marianne Langston ,  Adrian St. Clair Brown

    发明人： Frederick A. Hicks ,  Martin Ian Cooper ,  Marianne Langston ,  Adrian St. Clair Brown

    IPC分类号： A61K31/5377 ,  C07D413/14

    CPC分类号： C07D471/04

    摘要： The present invention is directed to the compound of formula (II), or a solvate thereof, or crystalline forms thereof; to a pharmaceutical composition comprising a pharmaceutically effective amount of the compound of formula (II), including crystalline forms thereof, and a pharmaceutically acceptable carrier; and to the use of a compound of formula (II), or crystalline forms thereof, for treating a patient suffering from, or subject to, a pathological condition capable of being ameliorated by inhibiting IKK-2, and methods related thereto.

    摘要翻译： 本发明涉及式（II）化合物或其溶剂化物或其结晶形式; 涉及药物组合物，其包含药学上有效量的式（II）化合物，包括其结晶形式和药学上可接受的载体; 以及使用式（II）化合物或其结晶形式用于治疗患有或受其抑制IKK-2能够改善的病理状况的患者及其相关方法。

    Salts of an IKK inhibitor
    2.
    发明申请
    Salts of an IKK inhibitor 审中-公开
    IKK抑制剂的盐

    公开(公告)号：US20090131422A1

    公开(公告)日：2009-05-21

    申请号：US12288595

    申请日：2008-10-22

    申请人： Frederick A. Hicks ,  Martin Ian Cooper ,  Adrian St Clair Brown

    发明人： Frederick A. Hicks ,  Martin Ian Cooper ,  Adrian St Clair Brown

    IPC分类号： A61K31/5377 ,  C07D413/14 ,  A61P29/00

    CPC分类号： C07D471/04

    摘要： The present invention is directed to the Tartrate, Mono-Hydrochloride, Malonate and p-Toluenesulfonate Salts of the compound of formula (I), or solvates thereof, or crystalline forms thereof; to a pharmaceutical composition comprising a pharmaceutically effective amount of the Salts, including crystalline forms thereof, and a pharmaceutically acceptable carrier; and to the use of the Salts, including crystalline forms thereof, for treating a patient suffering from, or subject to, a pathological condition capable of being ameliorated by inhibiting IKK-2, and methods related thereto.

    摘要翻译： 本发明涉及式（I）化合物或其溶剂合物或其结晶形式的酒石酸盐，单盐酸盐，丙二酸盐和对甲苯磺酸盐盐; 涉及包含药学有效量的盐，包括其结晶形式的药物组合物和药学上可接受的载体; 以及使用包括其结晶形式的盐，用于治疗患有或受其抑制IKK-2能够改善的病理状况的患者及其相关方法。