Process for adsorbing and removing endogenous cannabinoid
    1.
    发明授权
    Process for adsorbing and removing endogenous cannabinoid 失效
    吸收和去除内源性大麻素的方法

    公开(公告)号:US06790365B2

    公开(公告)日:2004-09-14

    申请号:US09961265

    申请日:2001-09-25

    IPC分类号: B01D1500

    摘要: There are provided an adsorbent which can effectively adsorb and remove endogenous cannabinoid in fluid, and a process for removing endogenous cannabinoid in fluid by means of the adsorbent. The adsorbent of endogenous cannabinoid comprising an adsorbent for endogenous cannabinoid comprising a water-insoluble material containing a substance whose solubility parameter &dgr; is at most 12 ((cal/cm3)1/2) is obtained. Endogenous cannabinoid in fluid can be effectively adsorbed and removed by contacting the adsorbent of endogenous cannabinoid with fluid containing endogenous cannabinoid.

    摘要翻译: 提供了能够有效吸附和去除流体中的内源大麻素的吸附剂,以及通过吸附剂除去流体中的内源大麻素的方法。 内源性大麻素的吸附剂包含内源性大麻素的吸附剂,其包含含有溶解度参数δ至多为12((cal / cm 3)1/2)的物质的水不溶性物质)。 通过使内源大麻素的吸附剂与含有内源性大麻素的液体接触,可以有效地吸附和去除流体中的内源性大麻素。

    Adsorbent for cytokine, method of adsorptive removal, and apparatus adsorptive removal
    6.
    发明申请
    Adsorbent for cytokine, method of adsorptive removal, and apparatus adsorptive removal 审中-公开
    用于细胞因子的吸附剂,吸附去除方法和装置吸附去除

    公开(公告)号:US20050063935A1

    公开(公告)日:2005-03-24

    申请号:US10499791

    申请日:2002-12-18

    摘要: The present invention provides an adsorbent for efficiently adsorbing and removing cytokine in liquid and a method for removing cytokine in liquid by the adsorbent. Also, the present invention provides an adsorber for removing cytokine in liquid. Specifically, an adsorbent for cytokine is obtained by immobilizing a compound having a log P value of at least 2.50 (P is the partition coefficient in an octanol-water system) on a water-insoluble carrier. By contacting a liquid containing cytokine with the adsorbent for cytokine, the cytokine in the liquid can be effectively adsorbed and removed. Furthermore, cytokine can be efficiently adsorbed and removed by an adsorber comprising a container having an inlet and an outlet for liquid and a means for preventing the adsorbent from flowing out of the container, which is filled with the adsorbent.

    摘要翻译: 本发明提供一种用于有效吸附和去除液体中的细胞因子的吸附剂,以及通过吸附剂除去液体中的细胞因子的方法。 此外,本发明提供了用于去除液体中的细胞因子的吸附器。 具体而言,通过将log P值为2.50以上的化合物(P为辛醇 - 水体系中的分配系数)固定在水不溶性载体上而获得细胞因子吸附剂。 通过使含有细胞因子的液体与细胞因子的吸附剂接触,液体中的细胞因子可以被有效地吸附和去除。 此外,可以通过包括具有用于液体的入口和出口的容器的吸附器有效地吸附和除去细胞因子,以及用于防止吸附剂从容器中流出的装置,其中填充有吸附剂。

    Method for producing microgranulated particle
    8.
    发明授权
    Method for producing microgranulated particle 失效
    微粒微粒生产方法

    公开(公告)号:US5547683A

    公开(公告)日:1996-08-20

    申请号:US244375

    申请日:1994-06-08

    摘要: The present invention relates to a method for producing a microgranulated particle having particle size of not more than 0.2 mm, wherein a fine powder with the average particle size of not more than 10 .mu.m, which is being agitated, tumbled or fluidized, is granulated, with a solution containing a binder alone or a binder and a surfactant being sprayed onto the surface thereof. The present invention allows to produce pharmaceutical preparations for poorly soluble and poorly absorbable drugs and preparations requiring a high content of the active ingredient. Also, it can provide an easy-to-handle powdery microgranulated particle in the field of food and fertilizers.

    摘要翻译: PCT No.PCT / JP93 / 01442 Sec。 371日期:1994年6月8日 102(e)日期1994年6月8日PCT提交1993年10月6日PCT公布。 出版物WO94 / 08709 日期:1994年04月28日本发明涉及一种粒径不大于0.2mm的微粒化微粒的制造方法,其特征在于,搅拌着平均粒径为10μm以下的细粉末, 或流化的颗粒,其中包含单独的粘合剂或粘合剂和表面活性剂的溶液喷涂到其表面上。 本发明允许制备难溶性和难吸收性药物和需要高含量活性成分的制剂的药物制剂。 此外,它可以在食品和肥料领域提供易于处理的粉状微粒化颗粒。