公开(公告)号：US09657055B2

公开(公告)日：2017-05-23

申请号：US14358821

申请日：2012-11-28

Applicant: GE Healthcare BioProcess R&D AB

Inventor： Hans J. Johansson ,  Ronnie Palmgren

IPC: B01D15/38 ,  C07K1/22 ,  C07K14/31 ,  C07K19/00 ,  B01J20/286 ,  B01J20/32 ,  C07K14/245 ,  B01D15/34

CPC classification number: C07K1/22 ,  B01D15/34 ,  B01D15/3809 ,  B01J20/285 ,  B01J20/286 ,  B01J20/289 ,  B01J20/3274 ,  C07K14/245 ,  C07K14/31 ,  C07K2319/00

Abstract: The invention discloses a polypeptide capable of binding immunoglobulins or immunoglobulin-containing proteins, which polypeptide comprises six or more domains of protein Z or the C domain of protein A or a functional variant thereof. It also discloses separation matrices comprising the polypeptide and methods of using the separation matrices for separation of immunoglobulins or immunoglobulin-containing proteins.

公开(公告)号：US20170247407A1

公开(公告)日：2017-08-31

申请号：US15596040

申请日：2017-05-16

Applicant: GE Healthcare BioProcess R&D AB

Inventor： Hans J. Johansson ,  Ronnie Palmgren

IPC: C07K1/22 ,  B01D15/38 ,  B01J20/285 ,  C07K14/31 ,  B01J20/289

CPC classification number: C07K1/22 ,  B01D15/34 ,  B01D15/3809 ,  B01J20/285 ,  B01J20/286 ,  B01J20/289 ,  B01J20/3274 ,  C07K14/245 ,  C07K14/31 ,  C07K2319/00

Abstract: The invention discloses a polypeptide capable of binding immunoglobulins or immunoglobulin-containing proteins, which polypeptide comprises six or more domains of protein Z or the C domain of protein A or a functional variant thereof. It also discloses separation matrices comprising the polypeptide and methods of using the separation matrices for separation of immunoglobulins or immunoglobulin-containing proteins.