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    TABLET PRODUCTION MODULE AND METHOD FOR CONTINUOUS PRODUCTION OF TABLETS
    1.
    发明申请
    TABLET PRODUCTION MODULE AND METHOD FOR CONTINUOUS PRODUCTION OF TABLETS 有权
    片剂生产模块和连续生产片剂的方法

    公开(公告)号：US20160310365A1

    公开(公告)日：2016-10-27

    申请号：US15204222

    申请日：2016-07-07

    申请人： GEA Pharma Systems Limited

    发明人： Jurgen BOECKX ,  Trevor Gordon PAGE ,  Michel Simon WALDRON

    IPC分类号： A61J3/10 ,  B30B15/30 ,  B29C43/02 ,  B29B13/06 ,  B29C43/50 ,  B29C43/58 ,  B29B7/48 ,  B29B7/72 ,  B30B11/00 ,  B29C43/34

    CPC分类号： A61J3/10 ,  B29B7/48 ,  B29B7/726 ,  B29B13/065 ,  B29C43/02 ,  B29C43/34 ,  B29C43/50 ,  B29C43/58 ,  B29C2043/5833 ,  B29K2105/0035 ,  B29K2105/251 ,  B30B11/005 ,  B30B15/308

    摘要： A method for continuous production of tablets, including providing a contained module comprising at least two inlets, at least one mixing unit, at least one analytical sensor, a tablet press, and at least one outlet for tablets, feeding an active pharmaceutical ingredient (API) to one of the at least two inlets, feeding an excipient to the other of the at least two inlets, mixing the material stream comprising the API and the excipient in the at least one mixing unit, measuring parameters of the contents of the material stream with the at least one analytical sensor upstream of the tablet press, controlling the two inlets and/or the mixing unit in response to the parameters measured, continuously supplying the tablet press with the material stream, controlling the speed of the tablet press in response to the parameters measured upstream of the tablet press, and discharging tablets at the at least one outlet.

    摘要翻译： 一种用于连续生产片剂的方法，包括提供包含至少两个入口的包含的模块，至少一个混合单元，至少一个分析传感器，压片机和用于片剂的至少一个出口，供给活性药物成分（API ）给所述至少两个入口中的一个入口，将赋形剂供给到所述至少两个入口中的另一个入口，将包含API和所述赋形剂的所述材料流混合在所述至少一个混合单元中，测量所述材料流的内容物的参数 与压片机上游的至少一个分析传感器，响应于测量的参数控制两个入口和/或混合单元，连续地向压片机供应材料流，以响应于压片机的速度控制 在压片机上游测量的参数，以及在至少一个出口处排出药片。