公开(公告)号：US12139706B2

公开(公告)日：2024-11-12

申请号：US17126693

申请日：2020-12-18

Applicant: Gen-Probe Incorporated

Inventor： Michael M. Becker ,  Mehrdad R. Majlessi

IPC: C12N15/11 ,  C07H21/02 ,  C07H21/04 ,  C12N15/10 ,  C12Q1/6806 ,  C12Q1/6834 ,  C12Q1/70

Abstract: Methods for capturing a target nucleic acid from a sample by using a capture probe that binds nonspecifically to the target nucleic acid and binds specifically to an immobilized probe via a specific binding pair that has one member on the capture probe and one member on the immobilized probe are disclosed. Compositions that include a capture probe that binds nonspecifically to a target nucleic acid and specifically to an immobilized probe via binding of members of a specific binding pair in a solution phase of a reaction mixture are disclosed.

公开(公告)号：US20240240271A1

公开(公告)日：2024-07-18

申请号：US18625389

申请日：2024-04-03

Applicant: Gen-Probe Incorporated

Inventor： Matthias Jost ,  Pamela Douglass ,  Daniel P. Kolk ,  Mehrdad R. Majlessi

IPC: C12Q1/70

CPC classification number: C12Q1/701 ,  C12Q1/70 ,  C12Q2561/101 ,  C12Q2563/107 ,  C12Q2600/16

Abstract: This disclosure concerns amplification primers, hybridization assay probes, compositions containing such primers and probes, and associated reagents, kits, and methods, that can be used to analyze samples for the presence of Influenza A virus, Influenza B virus, Respiratory Syncytial Virus A, and/or Respiratory Syncytial Virus B target nucleic acids.

公开(公告)号：US20240240270A1

公开(公告)日：2024-07-18

申请号：US18625379

申请日：2024-04-03

Applicant: Gen-Probe Incorporated

Inventor： Matthias Jost ,  Pamela Douglass ,  Daniel P. Kolk ,  Mehrdad R. Majlessi

IPC: C12Q1/70

CPC classification number: C12Q1/701 ,  C12Q1/70 ,  C12Q2561/101 ,  C12Q2563/107 ,  C12Q2600/16

Abstract: This disclosure concerns amplification primers, hybridization assay probes, compositions containing such primers and probes, and associated reagents, kits, and methods, that can be used to analyze samples for the presence of Influenza A virus, Influenza B virus, Respiratory Syncytial Virus A, and/or Respiratory Syncytial Virus B target nucleic acids.

公开(公告)号：US20220333162A1

公开(公告)日：2022-10-20

申请号：US17640740

申请日：2020-09-03

Applicant: Gen-Probe Incorporated

Inventor： Craig B. Clark ,  Damon K. Getman ,  Mehrdad R. Majlessi ,  Marion Walcher

IPC: C12Q1/689

Abstract: Hybridization probe reagents that specifically detect nucleic acids of C. trachomatis, including wildtype and/or variant sequences identified as FI-nvCT C1515T (SEQ ID NO: 17), JP-nvCT C1522T (SEQ ID NO: 12), US-nvCT G1526A (SEQ ID NO:22), and NO-nvCT G1523A (SEQ ID NO:27). Certain probes include nucleotide analogs to enhance desirable binding properties.

公开(公告)号：US20240240269A1

公开(公告)日：2024-07-18

申请号：US18625354

申请日：2024-04-03

Applicant: Gen-Probe Incorporated

Inventor： Matthias Jost ,  Pamela Douglass ,  Daniel P. Kolk ,  Mehrdad R. Majlessi

IPC: C12Q1/70

CPC classification number: C12Q1/701 ,  C12Q1/70 ,  C12Q2561/101 ,  C12Q2563/107 ,  C12Q2600/16

Abstract: This disclosure concerns amplification primers, hybridization assay probes, compositions containing such primers and probes, and associated reagents, kits, and methods, that can be used to analyze samples for the presence of Influenza A virus, Influenza B virus, Respiratory Syncytial Virus A, and/or Respiratory Syncytial Virus B target nucleic acids.

公开(公告)号：US11976337B2

公开(公告)日：2024-05-07

申请号：US16488909

申请日：2018-03-23

Applicant: GEN-PROBE INCORPORATED

Inventor： Matthias Jost ,  Pamela Douglass ,  Daniel P. Kolk ,  Mehrdad R. Majlessi

IPC: C12Q1/70

CPC classification number: C12Q1/701 ,  C12Q1/70 ,  C12Q2561/101 ,  C12Q2563/107 ,  C12Q2600/16

Abstract: This disclosure concerns amplification primers, hybridization assay probes, compositions containing such primers and probes, and associated reagents, kits, and methods, that can be used to analyze samples for the presence of Influenza A virus, Influenza B virus, Respiratory Syncytial Virus A, and/or Respiratory Syncytial Virus B target nucleic acids.

公开(公告)号：US11499193B2

公开(公告)日：2022-11-15

申请号：US16269307

申请日：2019-02-06

Applicant: GEN-PROBE INCORPORATED

Inventor： Sheila Aubin-Walker ,  Mehrdad R. Majlessi ,  Jimmykim Pham ,  Joshua Bousquet

IPC: C12Q1/6876 ,  C12Q1/6865 ,  C09B23/08 ,  C12Q1/6818

Abstract: Disclosed are formulations, including both liquid and lyophilized formulations, comprising a far-red dye probe and a non-linear surfactant or foamban. Also disclosed are related methods for preparing a lyophilized far-red dye probe formulation as well as related kits and diagnostic products.

公开(公告)号：US20210102201A1

公开(公告)日：2021-04-08

申请号：US17126693

申请日：2020-12-18

Applicant: Gen-Probe Incorporated

Inventor： Michael M. Becker ,  Mehrdad R. Majlessi

IPC: C12N15/11 ,  C12Q1/6834 ,  C07H21/02 ,  C07H21/04 ,  C12Q1/6806 ,  C12Q1/70 ,  C12N15/10

Abstract: Methods for capturing a target nucleic acid from a sample by using a capture probe that binds nonspecifically to the target nucleic acid and binds specifically to an immobilized probe via a specific binding pair that has one member on the capture probe and one member on the immobilized probe are disclosed. Compositions that include a capture probe that binds nonspecifically to a target nucleic acid and specifically to an immobilized probe via binding of members of a specific binding pair in a solution phase of a reaction mixture are disclosed.

公开(公告)号：US10900033B2

公开(公告)日：2021-01-26

申请号：US14990508

申请日：2016-01-07

Applicant: GEN-PROBE INCORPORATED

Inventor： Michael M. Becker ,  Mehrdad R. Majlessi

IPC: C12N15/11 ,  C12N15/10 ,  C12Q1/6834 ,  C12Q1/6806 ,  C07H21/02 ,  C07H21/04 ,  C12Q1/70

Abstract: Methods for capturing a target nucleic acid from a sample by using a capture probe that binds nonspecifically to the target nucleic acid and binds specifically to an immobilized probe via a specific binding pair that has one member on the capture probe and one member on the immobilized probe are disclosed. Compositions that include a capture probe that binds nonspecifically to a target nucleic acid and specifically to an immobilized probe via binding of members of a specific binding pair in a solution phase of a reaction mixture are disclosed.

公开(公告)号：US20240247325A1

公开(公告)日：2024-07-25

申请号：US18625400

申请日：2024-04-03

Applicant: Gen-Probe Incorporated

Inventor： Matthias Jost ,  Pamela Douglass ,  Daniel P. Kolk ,  Mehrdad R. Majlessi

IPC: C12Q1/70

CPC classification number: C12Q1/701 ,  C12Q1/70 ,  C12Q2561/101 ,  C12Q2563/107 ,  C12Q2600/16

Abstract: This disclosure concerns amplification primers, hybridization assay probes, compositions containing such primers and probes, and associated reagents, kits, and methods, that can be used to analyze samples for the presence of Influenza A virus, Influenza B virus, Respiratory Syncytial Virus A, and/or Respiratory Syncytial Virus B target nucleic acids.