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公开(公告)号：US20170112122A1
公开(公告)日：2017-04-27
申请号：US15399666
申请日：2017-01-05
Applicant: Genentech, Inc.
Inventor： Angela MEIER , Steven J. MEIER , Phillip DUFFY , Marcia COYNE , Kara CALHOUN
CPC classification number: A01N1/0221 , A01N1/0284 , C12N5/0018 , C12N5/0682 , C12N2510/02
Abstract: Provided herein are methods of freezing mammalian cells for storage or improving thaw recovery of cell banks comprising freezing mammalian cells in a freezing medium having a pH of 6.7 to 8.5.
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公开(公告)号：US20190002822A1
公开(公告)日：2019-01-03
申请号：US15997342
申请日：2018-06-04
Applicant: Genentech, Inc.
Inventor： Natarajan VIJAYASANKARAN , Steven J. MEIER , Sharat VARMA , Yi YANG
Abstract: Cell culture media comprising antioxidants are provided herein as are methods of using the media for cell culturing and polypeptide production from cells. Compositions comprising polypeptides, such as therapeutic polypeptides, produced by the methods herein are also provided.
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公开(公告)号：US20200315162A1
公开(公告)日：2020-10-08
申请号：US16798014
申请日：2020-02-21
Applicant: Genentech, Inc.
Inventor： Angela MEIER , Steven J. MEIER , Phillip DUFFY , Marcia COYNE , Kara CALHOUN
Abstract: Provided herein are methods of freezing mammalian cells for storage or improving thaw recovery of cell banks comprising freezing mammalian cells in a freezing medium having a pH of 6.7 to 8.5.
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公开(公告)号：US20190144817A1
公开(公告)日：2019-05-16
申请号：US16151904
申请日：2018-10-04
Applicant: Genentech, Inc.
Inventor： Natarajan VIJAYASANKARAN , Steven J. MEIER , Sharat VARMA , Yi YANG
Abstract: Cell culture media comprising antioxidants are provided herein as are methods of using the media for cell culturing and polypeptide production from cells. Compositions comprising polypeptides, such as therapeutic polypeptides, produced by the methods herein are also provided.
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5.发明申请CELL CULTURE COMPOSITIONS WITH ANTIOXIDANTS AND METHODS FOR POLYPEPTIDE PRODUCTION 审中-公开具有抗氧化剂的细胞培养物组合物和多肽生产方法公开(公告)号：US20160002593A1
公开(公告)日：2016-01-07
申请号：US14852311
申请日：2015-09-11
Applicant: Genentech, Inc.
Inventor： Natarajan VIJAYASANKARAN , Steven J. MEIER , Sharat VARMA , Yi YANG
CPC classification number: C12N5/0018 , C07K16/00 , C07K2317/14 , C12N2500/30 , C12N2500/33 , C12N2500/44 , C12N2500/46
Abstract: Cell culture media comprising antioxidants are provided herein as are methods of using the media for cell culturing and polypeptide production from cells. Compositions comprising polypeptides, such as therapeutic polypeptides, produced by the methods herein are also provided.
Abstract translation: 本文提供了包含抗氧化剂的细胞培养基，其方法是使用培养基用于细胞培养和从细胞产生多肽的方法。 还提供了通过本文方法制备的包含多肽（例如治疗性多肽）的组合物。
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Patent Agency Ranking
公开(公告)号：US20240084240A1
公开(公告)日：2024-03-14
申请号：US18464131
申请日：2023-09-08
Applicant: GENENTECH, INC.
Inventor： Arthi NARAYANAN , Aditya Avdhut WALVEKAR , Georo L. ZHOU , Nicholas RUMMEL , Zheng LI , Steven J. MEIER
Abstract: A method, system, and non-transitory computer readable medium for predicting cell viability of a cell culture in a bioreactor during a biomolecule manufacturing process are disclosed. In various embodiments, at least three manufacturing process parameters related to the process for manufacturing molecules are input into a machine learning model that is trained to predict cell viabilities. The trained machine learning model may then analyze the at least three manufacturing process parameters to generate an indicator of cell viability of the cell culture.
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公开(公告)号：US20210017488A1
公开(公告)日：2021-01-21
申请号：US17063322
申请日：2020-10-05
Applicant: Genentech, Inc.
Inventor： Natarajan VIJAYASANKARAN , Steven J. MEIER , Sharat VARMA , Yi YANG
Abstract: Cell culture media comprising antioxidants are provided herein as are methods of using the media for cell culturing and polypeptide production from cells. Compositions comprising polypeptides, such as therapeutic polypeptides, produced by the methods herein are also provided.
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公开(公告)号：US20170009015A1
公开(公告)日：2017-01-12
申请号：US15273155
申请日：2016-09-22
Applicant: Genentech, Inc.
Inventor： Ganesh Prasadh VISSVESVARAN , Robert David KISS , Steven J. MEIER , Inchan KWON , Kara CALHOUN , Kate WINCHESTER , Amelia ADAMS , Marion GLENN , Stefan KOENIG , Alan DEESE
Abstract: Provided herein are methods of preparing a poloxamer for use in a cell culture medium. Also provided herein are cell culture media containing the poloxamer prepared by the methods herein, as well as methods of using the media for cell culturing and polypeptide production from cells.
Abstract translation: 本文提供制备用于细胞培养基的泊洛沙姆的方法。 本文还提供了含有通过本文方法制备的泊洛沙姆的细胞培养基，以及使用培养基用于细胞培养和从细胞产生多肽的方法。
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9.发明申请CELL CULTURE COMPOSITIONS WITH ANTIOXIDANTS AND METHODS FOR POLYPEPTIDE PRODUCTION 审中-公开具有抗氧化剂的细胞培养物组合物和多肽生产方法公开(公告)号：US20140314779A1
公开(公告)日：2014-10-23
申请号：US14211416
申请日：2014-03-14
Applicant: Genentech, Inc.
Inventor： Natarajan VIJAYASANKARAN , Steven J. MEIER , Sharat VARMA , Yi YANG
CPC classification number: C12N5/0018 , C07K16/00 , C07K2317/14 , C12N2500/30 , C12N2500/33 , C12N2500/44 , C12N2500/46
Abstract: Cell culture media comprising antioxidants are provided herein as are methods of using the media for cell culturing and polypeptide production from cells. Compositions comprising polypeptides, such as therapeutic polypeptides, produced by the methods herein are also provided.
Abstract translation: 本文提供了包含抗氧化剂的细胞培养基，其方法是使用培养基用于细胞培养和从细胞产生多肽的方法。 还提供了通过本文方法制备的包含多肽（例如治疗性多肽）的组合物。
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公开(公告)号：US20240400976A1
公开(公告)日：2024-12-05
申请号：US18651221
申请日：2024-04-30
Applicant: Genentech, Inc.
Inventor： Natarajan VIJAYASANKARAN , Steven J. MEIER , Sharat VARMA , Yi YANG
Abstract: Cell culture media comprising antioxidants are provided herein as are methods of using the media for cell culturing and polypeptide production from cells. Compositions comprising polypeptides, such as therapeutic polypeptides. produced by the methods herein are also provided.
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