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公开(公告)号：US20210230562A1
公开(公告)日：2021-07-29
申请号：US17001015
申请日：2020-08-24
Applicant: Genomatica, Inc.
Inventor： Andreas Schirmer , Baolong ZHU , Emanuela Popova
Abstract: The disclosure relates to omega-hydroxylase-related fusion polypeptides that result in improved omega-hydroxylated fatty acid derivative production when expressed in recombinant host cells. The disclosure further relates to microorganisms for expressing the omega-hydroxylase-related fusion polypeptides for the production of omega-hydroxylated fatty acid derivatives.
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Patent Agency Ranking
公开(公告)号：US12180515B2
公开(公告)日：2024-12-31
申请号：US17834681
申请日：2022-06-07
Applicant: Genomatica, Inc.
Inventor： Andreas Schirmer , Baolong Zhu , Emanuela Popova
Abstract: The disclosure relates to omega-hydroxylase-related fusion polypeptides that result in improved omega-hydroxylated fatty acid derivative production when expressed in recombinant host cells. The disclosure further relates to microorganisms for expressing the omega-hydroxylase-related fusion polypeptides for the production of omega-hydroxylated fatty acid derivatives.
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公开(公告)号：US11339384B2
公开(公告)日：2022-05-24
申请号：US16500188
申请日：2018-04-03
Applicant: Genomatica, Inc.
Inventor： Angelica Zabala Bautista , Min Sun Park , Alma Itzel Ramos-Solis , Bernardo Moura Torres Da Costa , Behnaz Behrouzian , Donald E. Trimbur , Emanuela Popova , Qijun Hu , Stephen Bralley Del Cardayre
IPC: C12N9/16 , C12P7/6409
Abstract: The disclosure relates to engineered plant acyl-ACP thioesterases having improved activity for the production of medium-chain fatty acid derivatives including e.g., eight carbon and ten carbon fatty acids and fatty acid derivatives. The disclosure further relates to recombinant host cells comprising the engineered plant acyl-ACP thioesterases having improved activity for the production of medium-chain fatty acid derivatives. The disclosure also relates to methods of decreasing toxicity and improving production of medium-chain fatty acids and derivatives.
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公开(公告)号：US12157904B2
公开(公告)日：2024-12-03
申请号：US17715587
申请日：2022-04-07
Applicant: Genomatica, Inc.
Inventor： Angelica Zabala Bautista , Min Sun Park , Alma Itzel Ramos-Solis , Bernardo Moura Torres Da Costa , Behnaz Behrouzian , Donald E. Trimbur , Emanuela Popova , Qijun Hu , Stephen Bralley Del Cardayre
IPC: C12N9/16 , C12P7/6409 , C12P7/6436
Abstract: The disclosure relates to engineered plant acyl-ACP thioesterases having improved activity for the production of medium-chain fatty acid derivatives including e.g., eight carbon and ten carbon fatty acids and fatty acid derivatives. The disclosure further relates to recombinant host cells comprising the engineered plant acyl-ACP thioesterases having improved activity for the production of medium-chain fatty acid derivatives. The disclosure also relates to methods of decreasing toxicity and improving production of medium-chain fatty acids and derivatives.
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公开(公告)号：US11384341B2
公开(公告)日：2022-07-12
申请号：US17001015
申请日：2020-08-24
Applicant: Genomatica, Inc.
Inventor： Andreas Schirmer , Baolong Zhu , Emanuela Popova
Abstract: The disclosure relates to omega-hydroxylase-related fusion polypeptides that result in improved omega-hydroxylated fatty acid derivative production when expressed in recombinant host cells. The disclosure further relates to microorganisms for expressing the omega-hydroxylase-related fusion polypeptides for the production of omega-hydroxylated fatty acid derivatives.
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公开(公告)号：US10787648B2
公开(公告)日：2020-09-29
申请号：US16063198
申请日：2016-12-13
Applicant: GENOMATICA, INC.
Inventor： Andreas Schirmer , Baolong Zhu , Emanuela Popova
Abstract: The disclosure relates to omega-hydroxylase-related fusion polypeptides that result in improved omega-hydroxylated fatty acid derivative production when expressed in recombinant host cells. The disclosure further relates to microorganisms for expressing the omega-hydroxylase-related fusion polypeptides for the production of omega-hydroxylated fatty acid derivatives.
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