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公开(公告)号:US11384341B2
公开(公告)日:2022-07-12
申请号:US17001015
申请日:2020-08-24
Applicant: Genomatica, Inc.
Inventor: Andreas Schirmer , Baolong Zhu , Emanuela Popova
Abstract: The disclosure relates to omega-hydroxylase-related fusion polypeptides that result in improved omega-hydroxylated fatty acid derivative production when expressed in recombinant host cells. The disclosure further relates to microorganisms for expressing the omega-hydroxylase-related fusion polypeptides for the production of omega-hydroxylated fatty acid derivatives.
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公开(公告)号:US10787648B2
公开(公告)日:2020-09-29
申请号:US16063198
申请日:2016-12-13
Applicant: GENOMATICA, INC.
Inventor: Andreas Schirmer , Baolong Zhu , Emanuela Popova
Abstract: The disclosure relates to omega-hydroxylase-related fusion polypeptides that result in improved omega-hydroxylated fatty acid derivative production when expressed in recombinant host cells. The disclosure further relates to microorganisms for expressing the omega-hydroxylase-related fusion polypeptides for the production of omega-hydroxylated fatty acid derivatives.
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公开(公告)号:US11441130B2
公开(公告)日:2022-09-13
申请号:US15319272
申请日:2015-06-16
Applicant: GENOMATICA, INC.
Inventor: Baolong Zhu , Andreas W. Schirmer , Cindy Chang
IPC: C12N9/02 , C12P7/6409
Abstract: The disclosure relates to omega-hydroxylase-related fusion polypeptides that result in improved omega-hydroxylated fatty acid derivative production when expressed in recombinant host cells. The disclosure further relates to microorganisms for expressing the omega-hydroxylase-related fusion polypeptides for the production of omega-hydroxylated fatty acid derivatives.
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公开(公告)号:US20210071212A1
公开(公告)日:2021-03-11
申请号:US16915454
申请日:2020-06-29
Applicant: Genomatica, Inc.
Inventor: Andreas W. Schirmer , Haibo Wang , Stephen B. Del Cardayre , Zhihao Hu , Louis G. Hom , Baolong Zhu , Cindy Chang , Emanuela E. Popova
Abstract: The disclosure relates to omega-hydroxylated fatty acid derivatives and methods of producing them. Herein, the disclosure encompasses a novel and environmentally friendly production method that provides omega-hydroxylated fatty acid derivatives at high purity and yield. Further encompassed are recombinant microorganisms that produce omega-hydroxylated fatty acid derivatives through selective fermentation.
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公开(公告)号:US10711288B2
公开(公告)日:2020-07-14
申请号:US14897285
申请日:2014-06-16
Applicant: GENOMATICA, INC.
Inventor: Andreas W. Schirmer , Haibo Wang , Stephen B. Del Cardayre , Zhihao Hu , Louis G. Hom , Baolong Zhu , Cindy Chang , Emanuela E. Popova
IPC: C12P7/64 , C12N1/21 , C12N9/04 , C12N9/02 , C12N9/88 , C12N9/10 , C12N9/06 , C12N15/53 , C12N15/54 , C12N9/60 , C07K19/00 , C12P7/42 , C12N15/62 , C12P7/18 , C12N15/52
Abstract: The disclosure relates to omega-hydroxylated fatty acid derivatives and methods of producing them. Herein, the disclosure encompasses a novel and environmentally friendly production method that provides omega-hydroxylated fatty acid derivatives at high purity and yield. Further encompassed are recombinant microorganisms that produce omega-hydroxylated fatty acid derivatives through selective fermentation.
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公开(公告)号:US12180515B2
公开(公告)日:2024-12-31
申请号:US17834681
申请日:2022-06-07
Applicant: Genomatica, Inc.
Inventor: Andreas Schirmer , Baolong Zhu , Emanuela Popova
Abstract: The disclosure relates to omega-hydroxylase-related fusion polypeptides that result in improved omega-hydroxylated fatty acid derivative production when expressed in recombinant host cells. The disclosure further relates to microorganisms for expressing the omega-hydroxylase-related fusion polypeptides for the production of omega-hydroxylated fatty acid derivatives.
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公开(公告)号:US11034937B2
公开(公告)日:2021-06-15
申请号:US16414550
申请日:2019-05-16
Applicant: Genomatica, Inc.
Inventor: Derek L. Greenfield , Elizabeth J. Clarke , Eli S. Groban , Vikranth Arlagadda , Sungwon Lee , Xuezhi Li , Zhihao Hu , Baolong Zhu
Abstract: The disclosure relates to variant carboxylic acid reductase (CAR) enzymes for the improved production of fatty alcohols in recombinant host cells.
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公开(公告)号:US11981952B2
公开(公告)日:2024-05-14
申请号:US16915454
申请日:2020-06-29
Applicant: Genomatica, Inc.
Inventor: Andreas W. Schirmer , Haibo Wang , Stephen B. Del Cardayre , Zhihao Hu , Louis G. Hom , Baolong Zhu , Cindy Chang , Emanuela E. Popova
IPC: C12P7/6409 , C12N1/21 , C12N9/02 , C12N9/04 , C12N15/52 , C12N15/62 , C12P7/18 , C12P7/42 , C12P7/6436
CPC classification number: C12P7/6409 , C12N9/0006 , C12N9/0008 , C12N9/0071 , C12N9/0077 , C12N15/52 , C12N15/62 , C12P7/18 , C12P7/42 , C12P7/6436 , C12Y114/14001 , C12Y114/15003 , C07K2319/00 , C12Y101/00 , C12Y102/01042 , Y02E50/10
Abstract: The disclosure relates to omega-hydroxylated fatty acid derivatives and methods of producing them. Herein, the disclosure encompasses a novel and environmentally friendly production method that provides omega-hydroxylated fatty acid derivatives at high purity and yield. Further encompassed are recombinant microorganisms that produce omega-hydroxylated fatty acid derivatives through selective fermentation.
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公开(公告)号:US11421206B2
公开(公告)日:2022-08-23
申请号:US16661667
申请日:2019-10-23
Applicant: Genomatica, Inc.
Inventor: Baolong Zhu , Andreas W. Schirmer , Cindy Chang
IPC: C12N9/02 , C12N15/62 , C12P7/6409
Abstract: The disclosure relates to omega-hydroxylase-related fusion polypeptides that result in improved omega-hydroxylated fatty acid derivative production when expressed in recombinant host cells. The disclosure further relates to microorganisms for expressing the omega-hydroxylase-related fusion polypeptides for the production of omega-hydroxylated fatty acid derivatives.
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