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    Devices, systems and methods for in-vivo immunoassay
    2.
    发明授权
    Devices, systems and methods for in-vivo immunoassay 有权

    公开(公告)号：US10827953B2

    公开(公告)日：2020-11-10

    申请号：US15578505

    申请日：2016-06-02

    申请人： GIVEN IMAGING LTD.

    发明人： Elisha Rabinovitz ,  Osnat Sella-Tavor ,  Amit Pascal

    IPC分类号： A61B5/1455 ,  A61B5/07 ,  A61B5/00 ,  A61B5/145 ,  G01N33/558 ,  A61B5/01 ,  A61B5/05 ,  A61B5/1486

    摘要： A swallowable in-vivo device comprising a shell formed with at least one inlet extending across a shell wall and configured for allowing ingress of fluid at least into the shell; the shell accommodates therein a lateral flow (LF) arrangement configured for absorbing the fluid; the LF arrangement comprises a test zone configured for coming into contact, in-vivo, with a predetermined N substance present in the fluid or a compound comprising the substance, thereby causing a change in at least one property of the test zone; the shell further accommodates a sensor configured for sensing, in-vivo, the at least one property, at least when changed by interaction with the fluid; the LF arrangement has at least one curved segment, and at least one exposure portion juxtaposed with the inlet, configured for absorbing the fluid passing through the inlet into the shell.

    System and method for spatial and spectral imaging
    3.
    发明授权
    System and method for spatial and spectral imaging 有权
    空间和光谱成像的系统和方法

    公开(公告)号：US09360605B2

    公开(公告)日：2016-06-07

    申请号：US13743469

    申请日：2013-01-17

    申请人： GIVEN IMAGING LTD.

    发明人： Amit Pascal

    IPC分类号： A61B1/04 ,  A61B1/06 ,  G02B5/20 ,  H04N5/232 ,  A61B1/00 ,  G02B27/00

    CPC分类号： G02B5/201 ,  A61B1/00186 ,  A61B1/00188 ,  A61B1/041 ,  G02B27/0075 ,  G02B2207/129 ,  H04N5/23212

    摘要： A system and method for acquiring images containing spatial and spectral information of an object include acquiring defocused images using an optical system based on extended depth of field. The optical system further includes a filter array comprising an array of at least six different sub-filters that are arranged such that any group of four immediately adjacent sub-filters includes at least one red sub-filter, at least one green sub-filter and at least one blue sub-filter. The filter array is located at the aperture stop of the optical system. A coded mask is located at the focal plane of the optical system, and an imager is located beyond the focal plane such that images acquired by the imager are defocused. The images are refocused, and spectral and spatial information is restored by designated software.

    摘要翻译： 用于获取包含对象的空间和光谱信息的图像的系统和方法包括使用基于扩展景深的光学系统获取散焦图像。 该光学系统还包括一个滤波器阵列，该滤波器阵列包括至少六个不同的子滤波器的阵列，其被布置为使得四个紧邻的子滤波器的任何组包括至少一个红色子滤波器，至少一个绿色子滤波器和 至少一个蓝色子滤镜。 滤光片阵列位于光学系统的孔径光阑处。 编码掩模位于光学系统的焦平面处，并且成像器位于焦平面之外，使得由成像器获取的图像散焦。 图像被重新聚焦，并且通过指定的软件恢复光谱和空间信息。