公开(公告)号：US20170369532A1

公开(公告)日：2017-12-28

申请号：US15544730

申请日：2016-01-22

Applicant: GLAXOSMITHKLINE BIOLOGICALS, SA

Inventor： Andrea CARFI ,  Claudio CIFERRI ,  Yi XING

IPC: C07K14/005 ,  A61K39/00

CPC classification number: C07K14/005 ,  A61K38/00 ,  A61K39/00 ,  A61K39/12 ,  A61K39/245 ,  A61K39/25 ,  A61K39/42 ,  A61K2039/525 ,  A61K2039/55566 ,  C07K16/081 ,  C07K16/082 ,  C12N7/00 ,  C12N2710/16122 ,  C12N2710/16134 ,  C12N2710/16151 ,  C12N15/86 ,  C12N2710/16143 ,  C07K2319/50 ,  C07K16/088 ,  C12N2810/6009 ,  C12N2710/16161

Abstract: This disclosure provides modified cytomegalovirus (CMV) gL proteins and complexes comprising gL proteins. The modified gL proteins remain intact and are able to form complexes with other CMV proteins.