公开(公告)号：US20230390381A1

公开(公告)日：2023-12-07

申请号：US18082456

申请日：2022-12-15

Applicant: GLAXOSMITHKLINE BIOLOGICALS SA

Inventor： Ann-Muriel STEFF ,  Jean-Francois TOUSSAINT ,  Alessandra VITELLI

IPC: A61K39/155 ,  A61K39/235 ,  A61K39/12

CPC classification number: A61K39/155 ,  A61K39/235 ,  A61K39/12 ,  A61K2039/5256

Abstract: This disclosure provides immunogenic combinations that include a) an immunogenic component containing a peptide or polypeptide antigen of a respiratory pathogen; and b) an immunogenic component containing a nucleic acid encoding an antigen of the same respiratory pathogen, wherein the immunogenic components are formulated for concurrent, e.g., co-localized, administration. More specifically, the respiratory pathogen is respiratory syncytial virus (RSV). This disclosure also concerns provides the use of such immunogenic combinations, and methods for administering such immunogenic combinations to elicit an immune response specific for the respiratory pathogen.

公开(公告)号：US20170143820A1

公开(公告)日：2017-05-25

申请号：US15318490

申请日：2015-06-12

Applicant: GLAXOSMITHKLINE BIOLOGICALS SA

Inventor： Ann-Muriel STEFF ,  Jean-Francois TOUSSAINT ,  Alessandra VITELLI

IPC: A61K39/155

CPC classification number: A61K39/155 ,  A61K39/12 ,  A61K39/235 ,  A61K2039/5256 ,  A61K2039/545 ,  C12N2710/10343 ,  C12N2760/18534

Abstract: Immunogenic combinations that include a) an immunogenic component containing a peptide or polypeptide antigen of a respiratory pathogen; and b) an immunogenic component containing a nucleic acid encoding an antigen of the same respiratory pathogen, wherein the immunogenic components are formulated for concurrent administration are provided, as well as methods for making and for administering such immunogenic combinations to elicit an immune response specific for the respiratory pathogen.