公开(公告)号：US20230321213A1

公开(公告)日：2023-10-12

申请号：US18025273

申请日：2021-09-09

Applicant: GLAXOSMITHKLINE BIOLOGICALS SA

Inventor： Isabel DELANY ,  Giulia GIORDANO ,  Rosanna LEUZZI ,  Immaculada MARGARIT Y ROS

IPC: A61K39/095 ,  A61K39/39 ,  A61P31/04 ,  C12N1/20 ,  C12N1/36

CPC classification number: A61K39/095 ,  A61K39/39 ,  A61P31/04 ,  C12N1/205 ,  C12N1/36 ,  A61K2039/521

Abstract: The present invention relates to the field of neisserial vaccine compositions (particularly gonococcal vaccine compositions) and the use of such compositions in medicine. More particularly, the present invention relates to genetically modified gonococci of strain FA1090 and outer membrane vesicles obtained therefrom. The invention also provides a process for preparing the genetically modified gonococci of the invention as well as immunogenic compositions and vaccines comprising the outer membrane vesicles of the invention.