-
公开(公告)号：US20170298047A1
公开(公告)日：2017-10-19
申请号：US15509894
申请日：2015-09-09
发明人： Stephen John ATKINSON , David Jonathan HIRST , Philip G. HUMPHREYS , Matthew J. LINDON , Alexander G. PRESTON , Jonathan Thomas SEAL , Christopher Roland WELLAWAY
IPC分类号： C07D405/14 , C07D401/12
CPC分类号： C07D405/14 , C07D401/12
摘要： The present invention relates to specific novel compounds, pharmaceutical compositions containing such compounds and to their use in therapy as bromodomain inhibitors.
-
公开(公告)号：US20200289464A1
公开(公告)日：2020-09-17
申请号：US16753544
申请日：2018-10-04
发明人： Stephen John ATKINSON , Emmanuel Hubert DEMONT , Lee Andrew HARRISON , Simon Christopher Cranko LUCAS , Alexander G. PRESTON , Jonathan Thomas SEAL , Ian David WALL , Robert J. WATSON , James Michael WOOLVEN
IPC分类号： A61K31/4025 , A61K45/06 , C07D405/10 , C07D405/14 , C07D405/12 , C07D307/79 , C07D407/12 , C07D407/14 , C07D471/04 , C07D413/12 , A61K31/4155 , A61K31/4525 , A61K31/443 , A61K31/343 , A61K31/4192 , A61K31/506 , A61K31/501 , A61K31/397 , A61K31/351 , A61K31/4196
摘要： The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.
-
公开(公告)号：US20190202786A1
公开(公告)日：2019-07-04
申请号：US16303211
申请日：2017-05-22
发明人： Stephen John ATKINSON , Emmanuel Hubert DEMONT , Lee Andrew HARRISON , Etienne LEVERNIER , Alexander G. PRESTON , Jonathan Thomas SEAL , Ian David WALL , Robert J. WATSON , James Michael WOOLVEN
IPC分类号： C07D213/53 , C07D401/10 , C07D401/12 , C07D487/04 , C07D213/64
CPC分类号： C07D213/53 , C07D213/64 , C07D213/81 , C07D401/06 , C07D401/10 , C07D401/12 , C07D487/04
摘要： The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.
-
公开(公告)号：US20180282301A1
公开(公告)日：2018-10-04
申请号：US15762229
申请日：2016-09-20
发明人： Stephen John ATKINSON , Emmanuel Hubert , Lee Andrew HARRISON , Thomas HAYHOW , David HOUSE , Matthew J. LINDON , Alexander G. PRESTON , Jonathan Thomas SEAL , IAN David WALL , Robert J. WATSON , James Michael WOOLVEN
IPC分类号： C07D401/12 , C07D405/12 , A61K31/4433 , A61K31/4545 , A61K31/4427 , A61K31/443 , A61K31/496 , C07D409/12 , A61K31/4436 , C07D401/14 , A61K31/5377 , A61K31/541
CPC分类号： C07D401/12 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/4436 , A61K31/4545 , A61K31/496 , A61K31/5377 , A61K31/541 , C07D401/14 , C07D405/12 , C07D409/12
摘要： The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy
-
公开(公告)号：US20200009140A1
公开(公告)日：2020-01-09
申请号：US16489876
申请日：2018-02-27
发明人： Stephen John ATKINSON , Emmanuel Hubert DEMONT , Lee Andrew HARRISON , Etienne LEVERNIER , Alexander G. PRESTON , Jonathan Thomas SEAL , Ian David WALL , Robert J. WATSON , James Michael WOOLVEN
IPC分类号： A61K31/506 , A61K31/44 , C07D213/81 , A61K31/4439 , C07D401/12 , C07D413/12 , A61K31/444 , A61K31/501 , C07D417/12 , C07D401/14
摘要： The present invention is directed to pyridyl derivatives which are bromodomain inhibitors, pharmaceutical compositions comprising the compounds and the use of the compounds or the compositions in the treatment of various diseases or conditions
-
公开(公告)号：US20190381010A1
公开(公告)日：2019-12-19
申请号：US16489859
申请日：2018-02-27
发明人： Stephen John ATKINSON , Emmanuel Hubert DEMONT , Lee Andrew HARRISON , Gemma Michele LIWICKI , Simon Christopher Cranko LUCAS , Alexander G. PRESTON , Jonathan Thomas SEAL , Ian David WALL , Robert J. WATSON
IPC分类号： A61K31/4155 , C07D405/12 , A61K31/415 , C07D231/14 , C07D403/12 , C07D471/04 , A61K31/437 , A61K31/4439 , C07D401/12 , A61K31/422 , C07D413/12 , A61K31/5377 , C07D405/14 , C07D417/12 , A61K31/4192 , A61K31/433 , A61K31/4184 , A61K31/4245
摘要： The present invention is directed to pyrazole derivatives, pharmaceutical compositions comprising the compounds and the use of the compounds or the compositions in the treatment of various diseases.
-
![BENZO[B]FURANS AS BROMODOMAIN INHIBITORS](/abs-image/US/2019/05/23/US20190151279A1/abs.jpg.150x150.jpg)
公开(公告)号：US20190151279A1
公开(公告)日：2019-05-23
申请号：US16091577
申请日：2017-04-05
发明人： Stephen John ATKINSON , Emmanuel Hubert DEMONT , Lee Andrew HARRISON , Alexander G. PRESTON , Jonathan Thomas SEAL , Ian David WALL , Robert J. WATSON , James Michael WOOLVEN
CPC分类号： A61K31/343 , A61P19/02 , A61P31/04 , A61P31/10 , A61P31/12 , A61P35/00 , A61P37/00 , C07D307/79 , C07D307/80 , C07D405/12 , C07D407/12 , C07D409/12 , C07D413/12
摘要： The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.
-
公开(公告)号：US20200291009A1
公开(公告)日：2020-09-17
申请号：US16753543
申请日：2018-10-04
发明人： Stephen John ATKINSON , Emmanuel Hubert DEMONT , Lee Andrew HARRISON , Simon Christopher Cranko LUCAS , Alexander G. PRESTON , Jonathan Thomas SEAL , Ian David WALL , Robert J. WATSON , James Michael WOOLVEN
IPC分类号： C07D413/12 , C07D407/12 , C07D405/12 , C07D307/80
摘要： The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.
-
公开(公告)号：US20190119248A1
公开(公告)日：2019-04-25
申请号：US16091567
申请日：2017-04-05
发明人： Stephen John ATKINSON , Emmanuel Hubert DEMONT , Lee Andrew HARRISON , Etienne LEVERNIER , Alexander G. PRESTON , Jonathan Thomas SEAL , Ian David WALL , Robert J. WATSON , James Michael WOOLVEN
IPC分类号： C07D401/12 , A61K31/4545 , C07D405/12 , A61K31/443 , A61K31/4427 , A61K31/5377 , C07D413/12 , A61K31/496 , C07D213/81 , A61K31/454 , A61K31/453 , C07D401/14 , C07D405/14
摘要： The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.
-
公开(公告)号：US20180258044A1
公开(公告)日：2018-09-13
申请号：US15757199
申请日：2016-08-31
发明人： Stephen John ATKINSON , Helen Elizabeth AYLOTT , Anthony William James COOPER , Emmanuel Hubert DEMONT , Lee Andrew HARRISON , Thomas George Christopher HAYHOW , Matthew J. LINDON , Alexander G. PRESTON , Jonathan Thomas SEAL , Ian David WALL , Robert J. WATSON , James Michael WOOLVEN
IPC分类号： C07D213/82 , C07D405/06 , C07D401/06 , C07D471/04 , C07D413/06
CPC分类号： C07D213/82 , C07D401/06 , C07D405/06 , C07D413/06 , C07D471/04
摘要： The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy
-
-
-
-
-
-
-
-
-
搜索结果
10 条记录 (耗时 0.034 秒)
