公开(公告)号：US20220235388A1

公开(公告)日：2022-07-28

申请号：US17657787

申请日：2022-04-04

Applicant: GLYCOM A/S

Inventor： Margit Pedersen ,  Manos Papadakis ,  Peter Becker ,  Eric Samain ,  Pauline Peltier-Pain ,  Katrine Bych ,  Ted Johanson ,  Elise Champion ,  Gyula Dekany

IPC: C12P19/18 ,  C07K14/245 ,  C12N15/52 ,  C12P19/12 ,  C12N9/10 ,  C12N9/12 ,  C12N9/24 ,  C12N9/38

Abstract: The invention relates to a genetically modified microorganism for making a oligosaccharide, preferably of 3-8 monosaccharide units, more preferably of 3-5 monosaccharide units, particularly a HMO, which comprises one or more genes encoding a sucrose utilization system, so the microorganism can use sucrose as a carbon and energy source.

公开(公告)号：US11926858B2

公开(公告)日：2024-03-12

申请号：US17657787

申请日：2022-04-04

Applicant: GLYCOM A/S

Inventor： Margit Pedersen ,  Manos Papadakis ,  Peter Becker ,  Eric Samain ,  Pauline Peltier-Pain ,  Katrine Bych ,  Ted Johanson ,  Elise Champion ,  Gyula Dekany

IPC: C12P19/18 ,  C07K14/245 ,  C12N9/10 ,  C12N9/12 ,  C12N9/24 ,  C12N9/38 ,  C12N15/52 ,  C12P19/12

CPC classification number: C12P19/18 ,  C07K14/245 ,  C12N9/1029 ,  C12N9/1051 ,  C12N9/1205 ,  C12N9/2402 ,  C12N9/2471 ,  C12N15/52 ,  C12P19/12 ,  C12Y203/01018 ,  C12Y204/01149 ,  C12Y302/01023 ,  C12Y302/01026 ,  C12Y204/01094

Abstract: The invention relates to a genetically modified microorganism for making a oligosaccharide, preferably of 3-8 monosaccharide units, more preferably of 3-5 monosaccharide units, particularly a HMO, which comprises one or more genes encoding a sucrose utilization system, so the microorganism can use sucrose as a carbon and energy source.

公开(公告)号：US11293042B2

公开(公告)日：2022-04-05

申请号：US16927700

申请日：2020-07-13

Applicant: GLYCOM A/S

Inventor： Margit Pedersen ,  Manos Papadakis ,  Peter Becker ,  Eric Samain ,  Pauline Peltier-Pain ,  Katrine Bych ,  Ted Johanson ,  Elise Champion ,  Gyula Dekany

IPC: C12P19/00 ,  C12P19/12

Abstract: The invention relates to a genetically modified microorganism for making a oligosaccharide, preferably of 3-8 monosaccharide units, more preferably of 3-5 monosaccharide units, particularly a HMO, which comprises one or more genes encoding a sucrose utilization system, so the microorganism can use sucrose as a carbon and energy source.

公开(公告)号：US10731193B2

公开(公告)日：2020-08-04

申请号：US15321996

申请日：2015-06-29

Applicant: GLYCOM A/S

Inventor： Eric Samain ,  Pauline Peltier-Pain ,  Katrine Bych ,  Ted Johanson ,  Elise Champion ,  Gyula Dekany

IPC: C12P19/18 ,  C07K14/245 ,  C12N15/52 ,  C12N9/10 ,  C12N9/12 ,  C12N9/24 ,  C12N9/38

Abstract: The invention relates to a genetically modified microorganism for making a recombinant oligosaccharide, preferably of 3-8 monosaccharide units, more preferably of 3-5 monosaccharide units, particularly a HMO, which comprises one or more genes encoding a sucrose utilization system, so the microorganism can use sucrose as a carbon and energy source. The one or more genes encoding a sucrose utilization system are preferably one or more genes encoding a heterologous PTS-dependent sucrose utilization transport system, such as the scr genes.

公开(公告)号：US20170175154A1

公开(公告)日：2017-06-22

申请号：US15321996

申请日：2015-06-29

Applicant: GLYCOM A/S

Inventor： Eric Samain ,  Pauline Peltier-Pain ,  Katrine Bych ,  Ted Johanson ,  Elise Champion ,  Gyula Dekany

IPC: C12P19/18 ,  C12N9/12 ,  C12N15/52 ,  C12N9/10 ,  C12N9/38 ,  C07K14/245 ,  C12N9/24

CPC classification number: C12P19/18 ,  C07K14/245 ,  C12N9/1029 ,  C12N9/1051 ,  C12N9/1205 ,  C12N9/2402 ,  C12N9/2471 ,  C12N15/52 ,  C12Y203/01018 ,  C12Y204/01149 ,  C12Y302/01023 ,  C12Y302/01026

Abstract: The invention relates to a genetically modified microorganism for making a recombinant oligosaccharide, preferably of 3-8 monosaccharide units, more preferably of 3-5 monosaccharide units, particularly a HMO, which comprises one or more genes encoding a sucrose utilization system, so the microorganism can use sucrose as a carbon and energy source. The one or more genes encoding a sucrose utilization system are preferably one or more genes encoding a heterologous PTS-dependent sucrose utilization transport system, such as the scr genes.