公开(公告)号：US20230193335A1

公开(公告)日：2023-06-22

申请号：US17759270

申请日：2021-01-22

Applicant: GLYCOM A/S

Inventor： Margit PEDERSEN ,  Manos PAPADAKIS ,  Katrine Bych KAMPMANN

IPC: C12P19/04 ,  C12N9/10 ,  C12N15/70 ,  C07K14/24

CPC classification number: C12P19/04 ,  C12N9/1051 ,  C12Y204/01065 ,  C12Y204/01146 ,  C12N15/70 ,  C07K14/24

Abstract: The present inventive concept relates to a genetically modified cell enabled for the production of an oligosaccharide, preferably, an HMO, comprising a recombinant nucleic encoding a putative transporter protein of the MFS superfamily; and methods using said cell for the production of oligosaccharide(s), preferably an HMO.

公开(公告)号：US20230109937A1

公开(公告)日：2023-04-13

申请号：US17759276

申请日：2021-01-22

Applicant: GLYCOM A/S

Inventor： Margit PEDERSEN ,  Isotta D'ARRIGO ,  Katrine Bych KAMPMANN ,  Manos PAPADAKIS

IPC: C12N15/70 ,  C12P19/00 ,  C07H3/06 ,  C12N1/20

Abstract: The present invention relates to the field of recombinant production of biological molecules in genetically modified cells. More particularly, it relates to a method for recombinant production of human milk oligosaccharides (HMO) using a genetically modified cell expressing a protein of the major facilitator superfamily (MFS), the protein expressed being Fred.

公开(公告)号：US20230227876A1

公开(公告)日：2023-07-20

申请号：US17759273

申请日：2021-01-22

Applicant: GLYCOM A/S

Inventor： Margit PEDERSEN ,  Katrine Bych KAMPMANN

IPC: C12P19/00 ,  C07K14/24

CPC classification number: C12P19/00 ,  C07K14/24

Abstract: The present invention relates to the field of recombinant production of biological molecules in host cells. More particularly it relates to a method for recombinant production of human milk oligosaccharides (HMO) using a genetically modified cell expressing a protein of the major facilitator superfamily (MFS).

公开(公告)号：US20230072639A1

公开(公告)日：2023-03-09

申请号：US17759267

申请日：2021-01-22

Applicant: GLYCOM A/S

Inventor： Margit PEDERSEN ,  Isotta D'ARRIGO ,  Katrine Bych KAMPMANN ,  Manos PAPADAKIS

IPC: C12N5/10 ,  C12P19/00 ,  C12N15/74

Abstract: The present invention relates to the field of recombinant production of biological molecules in genetically modified cells. More particularly, it relates to a method for recombinant production of human milk oligosaccharides (HMO) using a genetically modified cell expressing a protein of the major facilitator superfamily (MFS), the protein expressed being Bad.