公开(公告)号：US20070284250A1

公开(公告)日：2007-12-13

申请号：US11685634

申请日：2007-03-13

申请人： Gary Magnant ,  Michael Finney ,  Todd Barbera ,  William Bowers ,  Diane Kozwich ,  Samuel Seymour ,  Robert Nelson ,  T. Boles

发明人： Gary Magnant ,  Michael Finney ,  Todd Barbera ,  William Bowers ,  Diane Kozwich ,  Samuel Seymour ,  Robert Nelson ,  T. Boles

IPC分类号： C07K1/26 ,  C07K1/28 ,  C25B9/08

CPC分类号： G01N27/44739 ,  G01N27/44795

摘要： Devices and methods are provided for more efficiently performing electrophoresis and electroblotting. A sandwich structure includes an electrophoresis gel affixed to a blotting membrane. A gel casting and/or running frame is used to hold the sandwich. A method and composition that allows separation of the gel and membrane after performing a combined electrophoresis and electroblotting operation so as to allow further operations to be performed individually upon the membrane, gel or both. A uniform electrophoretic field may be created by surrounding the sandwich structure using an insulating fluid; the insulating fluid is then swapped for a conducting fluid to allow application of an electroblotting field. An apparatus automatically manages fluid exchange and actuation of electrophoresis and electroblotting electrodes. A plurality of parallel cavities may be used to hold multiple gels or gel membrane sandwiches.

摘要翻译： 提供了更有效地进行电泳和电印迹的装置和方法。 夹心结构包括贴在印迹膜上的电泳凝胶。 凝胶浇注和/或运行框架用于夹持夹心物。 在进行组合电泳和电印迹操作之后允许分离凝胶和膜的方法和组合物，以允许在膜，凝胶或两者上分别进行进一步的操作。 可以通过使用绝缘流体围绕夹层结构来产生均匀的电泳场; 然后将绝缘流体交换用于导电流体以允许施加电印迹场。 一种装置自动地管理电泳和电印迹电极的流体交换和致动。 可以使用多个平行的空腔来容纳多个凝胶或凝胶膜三明治。

公开(公告)号：US20080031774A1

公开(公告)日：2008-02-07

申请号：US11734716

申请日：2007-04-12

申请人： Gary Magnant ,  Michael Finney ,  Todd Barbera ,  George Corey ,  T. Boles

发明人： Gary Magnant ,  Michael Finney ,  Todd Barbera ,  George Corey ,  T. Boles

IPC分类号： G01N33/00

CPC分类号： G01N35/00722 ,  B01L3/5085 ,  B01L3/50855 ,  B01L2200/142 ,  B01L2300/02 ,  B01L2300/023 ,  B01L2300/044 ,  B01L2300/0645 ,  B01L2300/0829 ,  G01N35/0092 ,  G01N2035/00891

摘要： A system has utility is guiding and tracking the execution of manual procedures. The system includes a support that holds multiple sample receptacles, computational circuitry to execute a protocol script that delivers instructions for executing various steps of the procedure, and a protocol progress sensor that advances the execution of the protocol script. The computer may be comparable in size to a support for holding the receptacles The receptacles be arranged in a frame, may be sealed with peelable or puncturable films and may include identifiers that are read by the system. The receptacles may be filled with a high heat capacity material to maintain a given temperature range. A variety of companion devices may interact with the system using the protocol script. An instrumented pipettor can communicate with the system for semi-automated execution of protocols.

摘要翻译： 系统的实用程序是指导和跟踪手动过程的执行。 该系统包括一个支持多个样本插座的支持，执行一个协议脚本的计算电路，该协议脚本提供用于执行该过程的各个步骤的指令，以及协议进程传感器，其执行协议脚本的执行。 计算机的尺寸可以与用于保持插座的支撑件相当。插座布置在框架中，可以用可剥离的或可穿刺的膜密封，并且可以包括由系统读取的标识符。 容器可以填充高热容材料以保持给定的温度范围。 各种伴侣设备可以使用协议脚本与系统进行交互。 仪器化移液器可与系统进行通信，以实现协议的半自动执行。

公开(公告)号：US20070286770A1

公开(公告)日：2007-12-13

申请号：US11685557

申请日：2007-03-13

申请人： Gary Magnant ,  William Bowers ,  Todd Barbera

发明人： Gary Magnant ,  William Bowers ,  Todd Barbera

IPC分类号： G01N21/01 ,  B01L11/00

CPC分类号： G01N35/00584 ,  B01L9/06 ,  B01L9/56 ,  B01L2200/16 ,  G01N21/645 ,  G01N35/0092 ,  G01N2035/00891 ,  G01N2035/0491 ,  Y10T29/49

摘要： A fluid handling apparatus for use with a fluid transfer instrument has a support member for supporting a receptacle having a plurality of wells (each well has an opening defining a well plane), and at least one detector operatively coupled with the support member. The detector detects when an instrument penetrates the well plane of at least one of the plurality of wells.

摘要翻译： 用于流体输送器具的流体处理装置具有用于支撑具有多个孔（每个井具有限定井平面的开口）的容器的支撑构件，以及与支撑构件可操作地联接的至少一个检测器。 检测器检测仪器何时穿透多个孔中的至少一个孔的井平面。

公开(公告)号：US20050230378A1

公开(公告)日：2005-10-20

申请号：US11152862

申请日：2005-06-15

申请人： Richard Abbott ,  Gary Magnant ,  William Glenn

发明人： Richard Abbott ,  Gary Magnant ,  William Glenn

IPC分类号： H05B3/20 ,  B21B27/08 ,  B22C9/06 ,  B22D17/22 ,  B29C45/73 ,  C23C4/02 ,  C23C4/06 ,  C23C4/10 ,  C23C4/12 ,  C23C16/46 ,  F26B13/04 ,  F27D1/16 ,  H01L21/00 ,  H01L21/31 ,  H05B3/00 ,  H05B3/10 ,  H05B3/12 ,  H05B3/14 ,  H05B3/68 ,  H05B3/16

CPC分类号： H01L21/67103 ,  B21B2027/086 ,  B29C45/73 ,  C23C4/02 ,  C23C4/12 ,  C23C4/123 ,  F27D1/1636 ,  H05B3/12 ,  Y10T29/49099

摘要： The present invention features a metallic resistive heater and uses thereof. The resistive heater includes a metallic component that is electrically conductive (i.e., has low resistivity) and an oxide, nitride, carbide, and/or boride derivative of the metallic component that is electrically insulating (i.e., has high resistivity). The resistivity is controlled in part by controlling the amount of oxide, nitride, carbide, and boride formation during the deposition of the metallic component and the derivative.

摘要翻译： 本发明的特征在于一种金属电阻加热器及其用途。 电阻加热器包括导电（即具有低电阻率）的金属部件和电绝缘（即具有高电阻率）的金属部件的氧化物，氮化物，碳化物和/或硼化物衍生物。 通过控制金属组分和衍生物沉积期间的氧化物，氮化物，碳化物和硼化物的形成量，部分地控制电阻率。

公开(公告)号：US20050247699A1

公开(公告)日：2005-11-10

申请号：US11151071

申请日：2005-06-13

申请人： Richard Abbott ,  Gary Magnant ,  William Glenn

发明人： Richard Abbott ,  Gary Magnant ,  William Glenn

IPC分类号： H05B3/20 ,  B21B27/08 ,  B22C9/06 ,  B22D17/22 ,  B29C45/73 ,  C23C4/02 ,  C23C4/06 ,  C23C4/10 ,  C23C4/12 ,  C23C16/46 ,  F26B13/04 ,  F27D1/16 ,  H01L21/00 ,  H01L21/31 ,  H05B3/00 ,  H05B3/10 ,  H05B3/12 ,  H05B3/14 ,  H05B3/68 ,  H05B3/16

CPC分类号： H01L21/67103 ,  B21B2027/086 ,  B29C45/73 ,  C23C4/02 ,  C23C4/12 ,  C23C4/123 ,  F27D1/1636 ,  H05B3/12 ,  Y02T50/6765 ,  Y10T29/49099

摘要： The present invention features a metallic resistive heater and uses thereof. The resistive heater includes a metallic component that is electrically conductive (i.e., has low resistivity) and an oxide, nitride, carbide, and/or boride derivative of the metallic component that is electrically insulating (i.e., has high resistivity). The resistivity is controlled in part by controlling the amount of oxide, nitride, carbide, and boride formation during the deposition of the metallic component and the derivative.

公开(公告)号：US20050236400A1

公开(公告)日：2005-10-27

申请号：US11151072

申请日：2005-06-13

申请人： Richard Abbott ,  Gary Magnant ,  William Glenn

发明人： Richard Abbott ,  Gary Magnant ,  William Glenn

IPC分类号： H05B3/20 ,  B21B27/08 ,  B22C9/06 ,  B22D17/22 ,  B29C45/73 ,  C23C4/02 ,  C23C4/06 ,  C23C4/10 ,  C23C4/12 ,  C23C16/46 ,  F26B13/04 ,  F27D1/16 ,  H01L21/00 ,  H01L21/31 ,  H05B3/00 ,  H05B3/10 ,  H05B3/12 ,  H05B3/14 ,  H05B3/68

CPC分类号： H01L21/67103 ,  B21B2027/086 ,  B29C45/73 ,  C23C4/02 ,  C23C4/12 ,  C23C4/123 ,  F27D1/1636 ,  H05B3/12 ,  Y02T50/6765 ,  Y10T29/49099

摘要： The present invention features a metallic resistive heater and uses thereof. The resistive heater includes a metallic component that is electrically conductive (i.e., has low resistivity) and an oxide, nitride, carbide, and/or boride derivative of the metallic component that is electrically insulating (i.e., has high resistivity). The resistivity is controlled in part by controlling the amount of oxide, nitride, carbide, and boride formation during the deposition of the metallic component and the derivative.

公开(公告)号：US20050247694A1

公开(公告)日：2005-11-10

申请号：US11149622

申请日：2005-06-10

申请人： Richard Abbott ,  Gary Magnant ,  William Glenn

发明人： Richard Abbott ,  Gary Magnant ,  William Glenn

IPC分类号： H05B3/20 ,  B21B27/08 ,  B22C9/06 ,  B22D17/22 ,  B29C45/73 ,  C23C4/02 ,  C23C4/06 ,  C23C4/10 ,  C23C4/12 ,  C23C16/46 ,  F26B13/04 ,  F27D1/16 ,  H01L21/00 ,  H01L21/31 ,  H05B3/00 ,  H05B3/10 ,  H05B3/12 ,  H05B3/14 ,  H05B3/68

CPC分类号： H01L21/67103 ,  B21B2027/086 ,  B29C45/73 ,  C23C4/02 ,  C23C4/12 ,  C23C4/123 ,  F27D1/1636 ,  H05B3/12 ,  Y02T50/6765 ,  Y10T29/49099

摘要： The present invention features a metallic resistive heater and uses thereof. The resistive heater includes a metallic component that is electrically conductive (i.e., has low resistivity) and an oxide, nitride, carbide, and/or boride derivative of the metallic component that is electrically insulating (i.e., has high resistivity). The resistivity is controlled in part by controlling the amount of oxide, nitride, carbide, and boride formation during the deposition of the metallic component and the derivative.

公开(公告)号：US20080029248A1

公开(公告)日：2008-02-07

申请号：US11685549

申请日：2007-03-13

申请人： Gary Magnant

发明人： Gary Magnant

IPC分类号： G01N27/447 ,  F25B21/02 ,  F25D17/00

CPC分类号： F28F13/18 ,  B01L7/00 ,  B01L2200/147 ,  B01L2300/0829 ,  B01L2300/12 ,  B01L2300/168 ,  B01L2300/1827 ,  B01L2300/185 ,  F25B39/02 ,  F25B40/00 ,  F25D23/00 ,  G01N27/44704

摘要： A temperature regulation system has a polished surface sufficiently smooth so as to reduce the emissivity of the surface. A conduit is in thermal proximity to the polished surface and is in communication with a source of coolant. The coolant is circulated through the conduit so as to transfer heat from the surface to the coolant. System may include a sprayed-on resistive heater. An a temperature controlled vessel has a heat transfer wall that is of an electrically conductive material that is coated with a durable thermally conductive and electrically nonconductive coating. The coating may be a sprayed on coating and the vessel may hold a buffer for performing electrophoresis.

摘要翻译： 温度调节系统具有足够光滑的抛光表面，以便降低表面的发射率。 导管处于与抛光表面接近热并与冷却剂源连通的位置。 冷却剂通过管道循环，以便将热量从表面传递到冷却剂。 系统可以包括喷涂电阻加热器。 温度控制容器具有导电材料的传热壁，其被涂覆有耐用的导热和非导电涂层。 涂层可以喷涂在涂层上，并且容器可以保持用于进行电泳的缓冲液。