公开(公告)号：US20200347118A1

公开(公告)日：2020-11-05

申请号：US16848564

申请日：2020-04-14

Applicant: Genentech, Inc.

Inventor： Amit MEHTA

IPC: C07K16/06 ,  C07K1/36 ,  C07K1/18 ,  C07K1/34

Abstract: The present invention relates to the field of protein purification. In particular, the invention concerns methods for increasing the filtration capacity of virus filters, by combined use of endotoxin removal and cation-exchange media in the prefiltration process.

公开(公告)号：US20210206836A1

公开(公告)日：2021-07-08

申请号：US17075238

申请日：2020-10-20

Applicant: Genentech, Inc.

Inventor： Deepa NADARAJAH ,  Amit MEHTA

IPC: C07K16/00 ,  B01D15/14 ,  C07K1/16 ,  B01D15/42 ,  C07K1/22

Abstract: The present invention provides methods for purifying a polypeptide from a composition comprising the polypeptide and at least one contaminant by overloading a chromatography material and eluting the product.

公开(公告)号：US20190023768A1

公开(公告)日：2019-01-24

申请号：US15956635

申请日：2018-04-18

Applicant: Genentech, Inc.

Inventor： Deepa NADARAJAH ,  Amit MEHTA

IPC: C07K16/00 ,  C07K1/22 ,  C07K1/16

Abstract: The present invention provides methods for purifying a polypeptide from a composition comprising the polypeptide and at least one contaminant by overloading a chromatography material and eluting the product.

公开(公告)号：US20240083980A1

公开(公告)日：2024-03-14

申请号：US18298233

申请日：2023-11-21

Applicant: Genentech, Inc.

Inventor： Amit MEHTA

IPC: C07K16/06 ,  C07K1/18 ,  C07K1/34 ,  C07K1/36

CPC classification number: C07K16/065 ,  C07K1/18 ,  C07K1/34 ,  C07K1/36

Abstract: The present invention relates to the field of protein purification. In particular, the invention concerns methods for increasing the filtration capacity of virus filters, by combined use of endotoxin removal and cation-exchange media in the prefiltration process.