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公开(公告)号：US09995755B2
公开(公告)日：2018-06-12
申请号：US14021947
申请日：2013-09-09
申请人： Genentech, Inc.
发明人： Joseph R. Arron , Richard W. Erickson , Michelle Freemer , Meredith Hazen , Guiquan Jia , John G. Matthews , Wendy Putnam , Heleen Scheerens , Yanan Zheng
IPC分类号： A61K39/00 , A61K45/00 , G01N33/68 , C07K16/28 , A61K39/395 , C07K16/18 , A61K31/522 , A61K31/573 , A61K45/06
CPC分类号： G01N33/6884 , A61K31/522 , A61K31/573 , A61K39/3955 , A61K39/39566 , A61K45/06 , C07K16/18 , C07K16/28 , G01N33/6887 , G01N33/6893 , G01N2333/475 , G01N2800/122 , G01N2800/52
摘要： Methods of diagnosing and treating disorders related to TH2 inhibition, including but not limited to asthma, are provided. Also provided are methods of selecting or identifying patients for treatment with certain therapeutic agents that are TH2 pathway inhibitors.
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公开(公告)号：US11226341B2
公开(公告)日：2022-01-18
申请号：US15992115
申请日：2018-05-29
申请人： GENENTECH, INC.
发明人： Joseph R. Arron , Richard W. Erickson , Michelle Freemer , Meredith Hazen , Guiquan Jia , John G. Matthews , Wendy Putnam , Heleen Scheerens , Yanan Zheng
IPC分类号： A61K39/395 , G01N33/68 , C07K16/28 , C07K16/24 , C07K16/18 , A61K31/522 , A61K31/573 , A61K45/06
摘要： Methods of diagnosing and treating disorders related to TH2 inhibition, including but not limited to asthma, are provided. Also provided are methods of selecting or identifying patients for treatment with certain therapeutic agents that are TH2 pathway inhibitors.
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3.发明申请公开(公告)号：US20180356429A1
公开(公告)日：2018-12-13
申请号：US15700790
申请日：2017-09-11
发明人： Alyssa Morimoto , Kun Peng , Heleen Scheerens , Fang Cai , Hans Hornauer
IPC分类号： G01N33/68
CPC分类号： G01N33/6869 , A61K2039/505 , A61K2039/55 , C07K16/244 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/76 , G01N33/50 , G01N33/574 , G01N2333/5437 , G01N2800/122 , G01N2800/52 , G01N2800/56
摘要： Methods of detecting and quantifying IL-13 are provided. Also provided are methods of diagnosing, selecting and identifying patients with Th2-associated diseases (Type 2-associated diseases) for treatment with certain therapeutic agents that are Th2 pathway inhibitors (Type 2 pathway inhibitors).
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公开(公告)号：US09684000B2
公开(公告)日：2017-06-20
申请号：US14021698
申请日：2013-09-09
申请人： Genentech, Inc.
发明人： Joseph R. Arron , Richard W. Erickson , Michelle Freemer , Meredith Hazen , Guiquan Jia , John G. Matthews , Wendy Putnam , Heleen Scheerens , Yanan Zheng
IPC分类号： C07K16/00 , G01N33/68 , C07K16/28 , A61K39/395 , C07K16/18 , A61K31/522 , A61K31/573 , A61K45/06
CPC分类号： G01N33/6884 , A61K31/522 , A61K31/573 , A61K39/3955 , A61K39/39566 , A61K45/06 , C07K16/18 , C07K16/28 , G01N33/6887 , G01N33/6893 , G01N2333/475 , G01N2800/122 , G01N2800/52
摘要： Methods of diagnosing and treating disorders related to TH2 inhibition, including but not limited to asthma, are provided. Also provided are methods of selecting or identifying patients for treatment with certain therapeutic agents that are TH2 pathway inhibitors.
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公开(公告)号：US20140044645A1
公开(公告)日：2014-02-13
申请号：US14021698
申请日：2013-09-09
申请人： Genentech, Inc.
发明人： Joseph R. Arron , Richard W. Erickson , Michelle Freemer , Meredith Hazen , Guiquan Jia , John G. Matthews , Wendy Putnam , Heleen Scheerens , Yanan Zheng
IPC分类号： G01N33/68 , A61K39/395 , C07K16/18
CPC分类号： G01N33/6884 , A61K31/522 , A61K31/573 , A61K39/3955 , A61K39/39566 , A61K45/06 , C07K16/18 , C07K16/28 , G01N33/6887 , G01N33/6893 , G01N2333/475 , G01N2800/122 , G01N2800/52
摘要： Methods of diagnosing and treating disorders related to TH2 inhibition, including but not limited to asthma, are provided. Also provided are methods of selecting or identifying patients for treatment with certain therapeutic agents that are TH2 pathway inhibitors.
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公开(公告)号：US20190120854A1
公开(公告)日：2019-04-25
申请号：US15992115
申请日：2018-05-29
申请人： GENENTECH, INC.
发明人： Joseph R. Arron , Richard W. Erickson , Michelle Freemer , Meredith Hazen , Guiquan Jia , John G. Matthews , Wendy Putnam , Heleen Scheerens , Yanan Zheng
IPC分类号： G01N33/68 , C07K16/24 , A61K31/573 , A61K31/522 , A61K45/06 , A61K39/395 , C07K16/28 , C07K16/18
摘要： Methods of diagnosing and treating disorders related to TH2 inhibition, including but not limited to asthma, are provided. Also provided are methods of selecting or identifying patients for treatment with certain therapeutic agents that are TH2 pathway inhibitors.
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公开(公告)号：US20140044702A1
公开(公告)日：2014-02-13
申请号：US14021947
申请日：2013-09-09
申请人： Genentech, Inc.
发明人： Joseph R. Arron , Richard W. Erickson , Michelle Freemer , Meredith Hazen , Guiquan Jia , John G. Matthews , Wendy Putnam , Heleen Scheerens , Yanan Zheng
IPC分类号： G01N33/68 , A61K31/522 , A61K45/06 , A61K39/395 , A61K31/573
CPC分类号： G01N33/6884 , A61K31/522 , A61K31/573 , A61K39/3955 , A61K39/39566 , A61K45/06 , C07K16/18 , C07K16/28 , G01N33/6887 , G01N33/6893 , G01N2333/475 , G01N2800/122 , G01N2800/52
摘要： Methods of diagnosing and treating disorders related to TH2 inhibition, including but not limited to asthma, are provided. Also provided are methods of selecting or identifying patients for treatment with certain therapeutic agents that are TH2 pathway inhibitors.
摘要翻译： 提供了诊断和治疗与TH2抑制有关的疾病的方法，包括但不限于哮喘。 还提供了选择或鉴定患者以治疗TH2途径抑制剂的某些治疗剂的方法。
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公开(公告)号：US20130243750A1
公开(公告)日：2013-09-19
申请号：US13754572
申请日：2013-01-30
申请人： GENENTECH, INC.
IPC分类号： C07K16/42 , A61K45/06 , A61K39/395
CPC分类号： C07K16/4291 , A61K39/39566 , A61K45/06 , C07K2317/56 , C07K2317/73 , C07K2317/76
摘要： This invention provides anti-IgE antibodies that bind to the M1′ segment of a human IgE and their use in treating and preventing IgE-mediated disorders, as well as kits comprising the anti-IgE antibodies.
摘要翻译： 本发明提供结合人IgE的M1'区段的抗IgE抗体及其在治疗和预防IgE介导的病症中的用途，以及包含抗IgE抗体的试剂盒。
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