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公开(公告)号:US20230226180A1
公开(公告)日:2023-07-20
申请号:US18154581
申请日:2023-01-13
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN
IPC: A61K39/395 , A61K31/7088 , A61K45/06 , C07K16/28 , A61K38/19 , A61K38/20 , A61K38/21 , A61K47/68 , A61P35/00 , A61K39/00 , A61K38/00 , C07K16/30 , C12N15/113 , C12N15/115
CPC classification number: A61K39/39558 , A61K31/7088 , A61K45/06 , C07K16/2803 , A61K38/193 , A61K38/20 , A61K38/217 , A61K47/6803 , A61K47/6851 , A61P35/00 , A61K39/00117 , A61K39/001113 , A61K39/001124 , A61K39/001129 , A61K39/001106 , A61K39/001128 , A61K39/001138 , A61K39/001104 , A61K39/001119 , A61K39/00114 , A61K39/001141 , A61K39/001166 , A61K39/001109 , A61K38/00 , A61K39/0011 , C07K16/30 , C12N15/1138 , C12N15/115 , Y02A50/30 , A61K2039/505 , A61K2039/5158 , A61K2039/545 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/76 , C12N2310/11 , C12N2310/12 , C12N2310/14
Abstract: The present disclosure provides methods comprising administering to the individual an effective amount of an agent that decreases or inhibits TIGIT expression and/or activity and an anti-cancer agent and/or an anti-cancer therapy. Further provided are kits comprising an anti-cancer agent, an agent that decreases or inhibits TIGIT expression and/or activity, or both, as well as instructions for use thereof.
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公开(公告)号:US20220064286A1
公开(公告)日:2022-03-03
申请号:US17526338
申请日:2021-11-15
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , C07K16/30 , A61K39/395 , A61K45/06 , A61K38/17
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:US20210253693A1
公开(公告)日:2021-08-19
申请号:US17244682
申请日:2021-04-29
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , C07K16/30 , A61K39/395 , A61K45/06 , A61K38/17
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:US20210032328A1
公开(公告)日:2021-02-04
申请号:US17064464
申请日:2020-10-06
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , C07K16/30 , A61K39/395 , A61K45/06 , A61K38/17
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:US20180169239A1
公开(公告)日:2018-06-21
申请号:US15890852
申请日:2018-02-07
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN
IPC: A61K39/395 , A61K47/68 , A61K31/7088 , A61K38/00 , A61K38/19 , A61K38/20 , A61K38/21 , C12N15/113 , A61K45/06 , C07K16/30 , C07K16/28 , C12N15/115 , A61K39/00
CPC classification number: A61K39/39558 , A61K31/7088 , A61K38/00 , A61K38/193 , A61K38/20 , A61K38/217 , A61K39/0011 , A61K45/06 , A61K47/6803 , A61K47/6851 , A61K2039/505 , A61K2039/5158 , A61K2039/545 , A61P35/00 , C07K16/2803 , C07K16/30 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/76 , C12N15/1138 , C12N15/115 , C12N2310/11 , C12N2310/12 , C12N2310/14 , Y02A50/466 , A61K2300/00
Abstract: The present disclosure provides methods comprising administering to the individual an effective amount of an agent that decreases or inhibits TIGIT expression and/or activity and an anti-cancer agent and/or an anti-cancer therapy. Further provided are kits comprising an anti-cancer agent, an agent that decreases or inhibits TIGIT expression and/or activity, or both, as well as instructions for use thereof.
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公开(公告)号:US20240082396A1
公开(公告)日:2024-03-14
申请号:US18486230
申请日:2023-10-13
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN
IPC: A61K39/395 , A61K31/7088 , A61K38/00 , A61K38/19 , A61K38/20 , A61K38/21 , A61K39/00 , A61K45/06 , A61K47/68 , A61P35/00 , C07K16/28 , C07K16/30 , C12N15/113 , C12N15/115
CPC classification number: A61K39/39558 , A61K31/7088 , A61K38/00 , A61K38/193 , A61K38/20 , A61K38/217 , A61K39/0011 , A61K39/001104 , A61K39/001106 , A61K39/001109 , A61K39/001113 , A61K39/001119 , A61K39/001124 , A61K39/001128 , A61K39/001129 , A61K39/001138 , A61K39/00114 , A61K39/001141 , A61K39/001166 , A61K39/00117 , A61K45/06 , A61K47/6803 , A61K47/6851 , A61P35/00 , C07K16/2803 , C07K16/30 , C12N15/1138 , C12N15/115 , A61K2039/505 , A61K2039/5158 , A61K2039/545 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/76 , C12N2310/11 , C12N2310/12 , C12N2310/14 , Y02A50/30
Abstract: The present disclosure provides methods comprising administering to the individual an effective amount of an agent that decreases or inhibits TIGIT expression and/or activity and an anti-cancer agent and/or an anti-cancer therapy. Further provided are kits comprising an anti-cancer agent, an agent that decreases or inhibits TIGIT expression and/or activity, or both, as well as instructions for use thereof.
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公开(公告)号:US20190119376A1
公开(公告)日:2019-04-25
申请号:US15994583
申请日:2018-05-31
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , A61K45/06 , A61K38/17 , C07K16/30 , A61K39/395
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:US20180186875A1
公开(公告)日:2018-07-05
申请号:US15895741
申请日:2018-02-13
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
CPC classification number: C07K16/28 , A61K38/177 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/2818 , C07K16/2827 , C07K16/2878 , C07K16/3061 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/567 , C07K2317/70 , C07K2317/75 , C07K2317/76 , C07K2317/90 , C07K2317/92 , C07K2317/94 , Y02A50/466
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:US20250108111A1
公开(公告)日:2025-04-03
申请号:US18978156
申请日:2024-12-12
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN
IPC: A61K39/395 , A61K31/7088 , A61K38/00 , A61K38/19 , A61K38/20 , A61K38/21 , A61K39/00 , A61K45/06 , A61K47/68 , A61P35/00 , C07K16/28 , C07K16/30 , C12N15/113 , C12N15/115
Abstract: The present disclosure provides methods comprising administering to the individual an effective amount of an agent that decreases or inhibits TIGIT expression and/or activity and an anti-cancer agent and/or an anti-cancer therapy. Further provided are kits comprising an anti-cancer agent, an agent that decreases or inhibits TIGIT expression and/or activity, or both, as well as instructions for use thereof.
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公开(公告)号:US20230279102A1
公开(公告)日:2023-09-07
申请号:US18062956
申请日:2022-12-07
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , A61K38/17 , C07K16/30 , A61K45/06 , A61K39/395
CPC classification number: C07K16/28 , A61K38/177 , A61K39/39558 , A61K45/06 , C07K16/2818 , C07K16/2827 , C07K16/2878 , C07K16/3061 , A61K2039/507 , C07K2317/34 , C07K2317/56 , C07K2317/90 , C07K2317/94
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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