公开(公告)号：US20240376223A1

公开(公告)日：2024-11-14

申请号：US18785404

申请日：2024-07-26

Applicant: Genentech, Inc.

Inventor： Yu-Waye Chu ,  Iraj Hosseini ,  Saroja Ramanujan ,  Kapil Gadkar ,  Chi-Chung Li

IPC: C07K16/28 ,  A61K31/573 ,  A61K39/00 ,  A61K39/395

Abstract: The invention provides methods of dosing for the treatment of cancers, such as B cell proliferative disorders, with anti-cluster of differentiation 20 (CD20)/anti-cluster of differentiation 3 (CD3) bispecific antibodies.

公开(公告)号：US11939396B2

公开(公告)日：2024-03-26

申请号：US16916822

申请日：2020-06-30

Applicant: Genentech, Inc.

Inventor： Xiaocheng Chen ,  Mark Dennis ,  Janet Jackman ,  James T. Koerber ,  Mason Lu ,  Henry R. Maun ,  Kathila Rajapaksa ,  Saroja Ramanujan ,  Tracy Staton ,  Lawren Wu ,  Tangsheng Yi

IPC: C07K16/40 ,  A61K39/395 ,  C07K16/24 ,  A61K39/00 ,  A61K45/06 ,  A61K47/10 ,  A61K47/18 ,  A61K47/22 ,  A61K47/26

CPC classification number: C07K16/40 ,  A61K39/3955 ,  A61K39/39591 ,  C07K16/244 ,  C12Y304/21059 ,  A61K2039/505 ,  A61K45/06 ,  A61K47/10 ,  A61K47/183 ,  A61K47/22 ,  A61K47/26 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/34 ,  C07K2317/40 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2317/94

Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.

公开(公告)号：US10738131B2

公开(公告)日：2020-08-11

申请号：US15893238

申请日：2018-02-09

Applicant: Genentech, Inc.

Inventor： Xiaocheng Chen ,  Mark Dennis ,  Janet Jackman ,  James T. Koerber ,  Mason Lu ,  Henry R. Maun ,  Kathila Rajapaksa ,  Saroja Ramanujan ,  Tracy Staton ,  Lawren Wu ,  Tangsheng Yi

IPC: C07K16/40 ,  A61K39/395 ,  A61K47/18 ,  A61K47/22 ,  A61K47/26 ,  A61K47/10 ,  A61K45/06 ,  C07K16/24 ,  A61K39/00

Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.

公开(公告)号：US11466094B2

公开(公告)日：2022-10-11

申请号：US15813657

申请日：2017-11-15

Applicant: Genentech, Inc.

Inventor： Yu-Waye Chu ,  Iraj Hosseini ,  Saroja Ramanujan ,  Kapil Gadkar ,  Chi-Chung Li

IPC: A61K31/573 ,  C07K16/28 ,  A61K39/395 ,  A61K39/00

Abstract: The invention provides methods of dosing for the treatment of cancers, such as B cell proliferative disorders, with anti-cluster of differentiation 20 (CD20)/anti-cluster of differentiation 3 (CD3) bispecific antibodies.

公开(公告)号：US10752703B2

公开(公告)日：2020-08-25

申请号：US16544421

申请日：2019-08-19

Applicant: Genentech, Inc.

Inventor： Xiaocheng Chen ,  Mark Dennis ,  Janet Jackman ,  James T. Koerber ,  Mason Lu ,  Henry R. Maun ,  Kathila Rajapaksa ,  Saroja Ramanujan ,  Tracy Staton ,  Lawren Wu ,  Tangsheng Yi

IPC: C07K16/40 ,  A61K39/395 ,  A61K39/00 ,  A61K47/18 ,  A61K47/22 ,  A61K47/26 ,  A61K47/10 ,  A61K45/06 ,  C07K16/24

Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.

公开(公告)号：US20240368306A1

公开(公告)日：2024-11-07

申请号：US18439879

申请日：2024-02-13

Applicant: Genentech, Inc.

Inventor： Xiaocheng CHEN ,  Mark Dennis ,  Janet Jackman ,  James T. Koerber ,  Mason Lu ,  Henry R. Maun ,  Kathila Rajapaksa ,  Saroja Ramanujan ,  Tracy Staton ,  Lawren Wu ,  Tangsheng Yi

IPC: C07K16/40 ,  A61K39/00 ,  A61K39/395 ,  A61K45/06 ,  A61K47/10 ,  A61K47/18 ,  A61K47/22 ,  A61K47/26 ,  C07K16/24

Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.

公开(公告)号：US20240331829A1

公开(公告)日：2024-10-03

申请号：US18626741

申请日：2024-04-04

Applicant: Genentech, Inc.

Inventor： Mohammad Jafarnejad ,  Louis Russell Joslyn ,  Iraj Hosseini ,  Saroja Ramanujan

IPC: G16H20/17 ,  G16B15/30

CPC classification number: G16H20/17 ,  G16B15/30

Abstract: The present disclosure relates generally to the field of immunology and oncology, and particularly to systems and methods for use in treating various disorders, such as those associated with cell signaling mediated by cytokines. Some embodiments of the disclosure provide quantitative system pharmacology (QSP) models developed to capture the complex interactions between drug pharmacokinetics and the differential expansion of multiple immune cell subsets across tissues and tumor.

公开(公告)号：US20230242659A1

公开(公告)日：2023-08-03

申请号：US18173417

申请日：2023-02-23

Applicant: Genentech, Inc.

Inventor： Yu-Waye Chu ,  Iraj Hosseini ,  Saroja Ramanujan ,  Kapil Gadkar ,  Chi-Chung Li

IPC: C07K16/28 ,  A61K39/395 ,  A61K31/573

CPC classification number: C07K16/2887 ,  C07K16/2809 ,  C07K16/2827 ,  A61K39/3955 ,  C07K16/2866 ,  A61K31/573 ,  C07K2317/41 ,  C07K2317/24 ,  A61K2039/545

Abstract: The invention provides methods of dosing for the treatment of cancers, such as B cell proliferative disorders, with anti-cluster of differentiation 20 (CD20)/anti-cluster of differentiation 3 (CD3) bispecific antibodies.