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公开(公告)号:US09688745B2
公开(公告)日:2017-06-27
申请号:US14981643
申请日:2015-12-28
Applicant: Genentech, Inc. , AIMM THERAPEUTICS B.V.
Inventor: Tim Beaumont , Mark Jeroen Kwakkenbos , Eric J. Brown , John Hiroshi Morisaki , Wouter L. W. Hazenbos , Sanjeev Mariathasan , Kimberly Kajihara , Yi Xia
CPC classification number: G01N33/5091 , C07K16/1271 , C07K16/1278 , C07K2317/21 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/567 , G01N33/6854 , G01N33/6893 , G01N2469/10 , G01N2800/26
Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.
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公开(公告)号:US09266943B2
公开(公告)日:2016-02-23
申请号:US14103715
申请日:2013-12-11
Applicant: Genentech, Inc. , AIMM THERAPEUTICS B.V.
Inventor: Tim Beaumont , Mark Jeroen Kwakkenbos , Eric J. Brown , John Hiroshi Morisaki , Wouter L. W. Hazenbos , Sanjeev Mariathasan , Kimberly Kajihara , Yi Xia
CPC classification number: G01N33/5091 , C07K16/1271 , C07K16/1278 , C07K2317/21 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/567 , G01N33/6854 , G01N33/6893 , G01N2469/10 , G01N2800/26
Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.
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公开(公告)号:US20160222096A1
公开(公告)日:2016-08-04
申请号:US14981643
申请日:2015-12-28
Applicant: Genentech, Inc. , AIMM THERAPEUTICS B.V.
Inventor: Tim Beaumont , Mark Jeroen Kwakkenbos , Eric J. Brown , John Hiroshi Morisaki , Wouter L.W. Hazenbos , Sanjeev Mariathasan , Kimberly Kajihara , Yi Xia
IPC: C07K16/12
CPC classification number: G01N33/5091 , C07K16/1271 , C07K16/1278 , C07K2317/21 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/567 , G01N33/6854 , G01N33/6893 , G01N2469/10 , G01N2800/26
Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.
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公开(公告)号:US20180125995A1
公开(公告)日:2018-05-10
申请号:US15612193
申请日:2017-06-02
Applicant: Genentech, Inc.
Inventor: Eric Brown , Wouter Hazenbos , Isidro Hotzel , Kimberly Kajihara , Sophie M. Lehar , Sanjeev Mariathasan , Thomas Pillow , Leanna Staben , Vishal Verma , Binqing Wei , Yi Xia , Min Xu
IPC: A61K47/68 , C07K16/12 , A61K31/5383 , A61K45/06 , A61P31/04
CPC classification number: A61K47/6803 , A61K31/5383 , A61K45/06 , A61K47/6835 , A61K47/6889 , A61P31/04 , C07K16/1271 , C07K2317/21
Abstract: The invention provides rF1 antibody antibiotic conjugates and methods of using same.
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公开(公告)号:US09090677B2
公开(公告)日:2015-07-28
申请号:US13786215
申请日:2013-03-05
Applicant: Genentech, Inc. , AIMM Therapeutics B. V.
Inventor: Tim Beaumont , Mark Jeroen Kwakkenbos , Eric J. Brown , John Hiroshi Morisaki , Wouter L. W. Hazenbos , Sanjeev Mariathasan , Kimberly Kajihara , Yi Xia
CPC classification number: G01N33/5091 , C07K16/1271 , C07K16/1278 , C07K2317/21 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/567 , G01N33/6854 , G01N33/6893 , G01N2469/10 , G01N2800/26
Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.
Abstract translation: 本发明提供能够特异性结合革兰氏阳性细菌的改进的结合化合物。 提供了完全人类的结合化合物,可在人类个体中实现治疗应用。
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公开(公告)号:US09458228B2
公开(公告)日:2016-10-04
申请号:US14728826
申请日:2015-06-02
Applicant: Genentech, Inc. , AIMM Therapeutics B.V.
Inventor: Tim Beaumont , Mark Jeroen Kwakkenbos , Eric J. Brown , John Hiroshi Morisaki , Wouter L. W. Hazenbos , Sanjeev Mariathasan , Kimberly Kajihara , Yi Xia
IPC: C07K16/12
CPC classification number: G01N33/5091 , C07K16/1271 , C07K16/1278 , C07K2317/21 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/567 , G01N33/6854 , G01N33/6893 , G01N2469/10 , G01N2800/26
Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.
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公开(公告)号:US09927428B2
公开(公告)日:2018-03-27
申请号:US15246301
申请日:2016-08-24
Applicant: Genentech, Inc. , AIMM Therapeutics B.V.
Inventor: Tim Beaumont , Mark Jeroen Kwakkenbos , Eric J. Brown , John Hiroshi Morisaki , Wouter L. W. Hazenbos , Sanjeev Mariathasan , Kimberly Kajihara , Yi Xia
CPC classification number: G01N33/5091 , C07K16/1271 , C07K16/1278 , C07K2317/21 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/567 , G01N33/6854 , G01N33/6893 , G01N2469/10 , G01N2800/26
Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.
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公开(公告)号:US09399673B2
公开(公告)日:2016-07-26
申请号:US13786206
申请日:2013-03-05
Applicant: Genentech, Inc. , AIMM Therapeutics B.V.
Inventor: Tim Beaumont , Mark Jeroen Kwakkenbos , Eric J. Brown , John Hiroshi Morisaki , Wouter L. W. Hazenbos , Sanjeev Mariathasan , Kimberly Kajihara , Yi Xia
IPC: C07K16/12
CPC classification number: G01N33/5091 , C07K16/1271 , C07K16/1278 , C07K2317/21 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/567 , G01N33/6854 , G01N33/6893 , G01N2469/10 , G01N2800/26
Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.
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