公开(公告)号：US20150001420A1

公开(公告)日：2015-01-01

申请号：US13927543

申请日：2013-06-26

Applicant: General Electric Company

Inventor： Rajesh Veera Venkata Lakshmi Langoju ,  Abhijit Vishwas Patil ,  Sridhar Dasaratha ,  Vignesh Thirukazhukundram Subrahmaniam ,  Dmitry Vladimirovich Dylov ,  Siavash Yazdanfar ,  Stephen B. Solomon

IPC: G01N21/64

CPC classification number: G01N21/31 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/6849

Abstract: A method for classifying a tissue sample of a biopsy specimen into one of a plurality of classes is presented. The method includes receiving a light from at least one location of the tissue sample including a plurality of chromophores, wherein the received light comprises at least one of an attenuated illumination light and a re-emitted light. The method further includes processing a spectrum of the received light to determine a feature for each of the chromophores in the at least one location of the tissue sample. In addition, the method includes estimating a Z-score for each of the chromophores based on the determined feature. Also, the method includes classifying the tissue sample into one of the plurality of classes based on the estimated Z-score for each of the chromophores.

Abstract translation: 提出了将活检标本的组织样本分类为多个类别之一的方法。 该方法包括从包括多个发色团的组织样本的至少一个位置接收光，其中所接收的光包括衰减照明光和再发射光中的至少一个。 该方法还包括处理所接收的光的光谱以确定组织样本的至少一个位置中的每个发色团的特征。 此外，该方法包括基于所确定的特征来估计每个发色团的Z分数。 此外，该方法包括基于每个发色团的估计的Z分数将组织样本分类为多个类中的一个。

公开(公告)号：US08912512B1

公开(公告)日：2014-12-16

申请号：US13927543

申请日：2013-06-26

Applicant: General Electric Company

Inventor： Rajesh Veera Venkata Lakshmi Langoju ,  Abhijit Vishwas Patil ,  Sridhar Dasaratha ,  Vignesh Thirukazhukundram Subrahmaniam ,  Dmitry Vladimirovich Dylov ,  Siavash Yazdanfar ,  Stephen B. Solomon

IPC: G01N21/64

CPC classification number: G01N21/31 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/6849

Abstract: A method for classifying a tissue sample of a biopsy specimen into one of a plurality of classes is presented. The method includes receiving a light from at least one location of the tissue sample including a plurality of chromophores, wherein the received light comprises at least one of an attenuated illumination light and a re-emitted light. The method further includes processing a spectrum of the received light to determine a feature for each of the chromophores in the at least one location of the tissue sample. In addition, the method includes estimating a Z-score for each of the chromophores based on the determined feature. Also, the method includes classifying the tissue sample into one of the plurality of classes based on the estimated Z-score for each of the chromophores.

Abstract translation: 提出了将活检标本的组织样本分类为多个类别之一的方法。 该方法包括从包括多个发色团的组织样本的至少一个位置接收光，其中所接收的光包括衰减照明光和再发射光中的至少一个。 该方法还包括处理所接收的光的光谱以确定组织样本的至少一个位置中的每个发色团的特征。 此外，该方法包括基于所确定的特征来估计每个发色团的Z分数。 此外，该方法包括基于每个发色团的估计的Z分数将组织样本分类为多个类中的一个。