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1.发明申请SYSTEM AND METHOD FOR ATTACHING A BIOPSY COLLECTING DEVICE TO A SPECTROSCOPY SYSTEM 审中-公开将生物收集装置连接到光谱系统的系统和方法公开(公告)号：US20150182204A1
公开(公告)日：2015-07-02
申请号：US14657085
申请日：2015-03-13
Applicant: General Electric Company
Inventor： Siavash Yazdanfar , Victor Petrovich Ostroverkhov , Dmitry Vladimirovich Dylov , Stephen B. Solomon , Jeremy C. Durack
IPC: A61B10/02
CPC classification number: A61B10/0233 , A61B10/0275 , A61B2010/0208 , A61B2560/0456 , G01N1/31
Abstract: A biopsy collecting device includes a needle unit comprising a biopsy specimen. Also, the biopsy collecting device includes an activator unit operatively coupled to the needle unit and including a channel at a bottom surface of the activator unit, wherein the channel is configured to detachably couple the biopsy collecting device to an attaching unit of a spectroscopy system.
Abstract translation: 活组织检查收集装置包括包括活组织检查样本的针单元。 此外，活检收集装置包括可操作地联接到针单元并且在活化器单元的底表面处包括通道的活化单元，其中通道被配置为将活检收集装置可拆卸地连接到光谱系统的附接单元。
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公开(公告)号：US20180291803A1
公开(公告)日：2018-10-11
申请号：US16000810
申请日：2018-06-05
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Bernard Patrick Belay , Waseem Ibrahim Faidi , Peter William Lorraine , Mohamed Ahmed Ali , Siavash Yazdanfar , Ying Fan , Edward James Nieters , David Mills , Nicole Tibbetts, JR.
Abstract: A cleaning system and method use an ultrasound probe, a coupling mechanism, and a controller to clean equipment of a vehicle system. The ultrasound probe enters into an engine. The ultrasound probe emits ultrasound pulses and the coupling mechanism provides an ultrasound coupling medium between the ultrasound probe and one or more components of the engine. The controller drives the ultrasound probe to deliver the ultrasound pulse through the coupling medium to a surface of the one or more components of the engine. The ultrasound probe delivers the ultrasound pulse to remove deposits from the one or more components of the engine.
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公开(公告)号：US20170151736A1
公开(公告)日：2017-06-01
申请号：US14955632
申请日：2015-12-01
Applicant: General Electric Company
Inventor： Mark Marshall Meyers , Masako Yamada , Paul Richard Myers , Scott Michael Miller , Siavash Yazdanfar
CPC classification number: B29D11/00663 , B29C33/306 , B29C33/424 , B29C45/2673 , B29C45/372 , B29L2011/00 , G02B6/0038 , G02B6/0058 , G02B6/0061 , G02B6/0063 , G02B6/0065 , G02B6/0095
Abstract: A modular method of manufacturing a waveguide is disclosed. The method includes positioning a mold insert including a plurality of mold prototypes, along at least one side wall of a molding equipment such that micro-optic structures of each mold prototype in the plurality of mold prototypes, faces a mold cavity. Each mold prototype extends along a length of the mold insert and the plurality of mold prototypes is disposed adjacent one another along a height of the mold insert. The method further includes feeding a material into the mold cavity for molding the material in the mold cavity to generate waveguide including a major surface having an optical pattern, where the optical pattern includes a plurality of elongated facets. Each of the plurality of elongated facets extends into the major surface and along a length of the waveguide. Further, the optical pattern extends along a height of the waveguide.
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公开(公告)号：US08977331B2
公开(公告)日：2015-03-10
申请号：US13713745
申请日：2012-12-13
Applicant: General Electric Company
CPC classification number: A61B5/0071 , A61B1/00009 , A61B1/043 , A61B1/0638 , A61B5/4893 , A61B5/6847 , A61B17/00 , A61B90/361 , A61B90/37 , A61B2090/373 , A61B2505/05 , A61B2576/02
Abstract: Systems and methods for imaging are presented. The method includes producing excitation light configured to induce fluorescence in an imaging agent that selectively binds to a target species in a region of interest (ROI) of a subject that also includes a background species. A first and a second spectral region are selected such that a determined difference between fluorescence corresponding to the target and the background species in the first spectral region differs from a corresponding difference in the second spectral region. First and second fluorescence images are generated from the fluorescence corresponding to the first and second spectral regions. Additionally, a fluorescence ratio for the background species in the first and second fluorescence image is determined. The first fluorescence image is then multiplied or divided with the determined ratio to generate an intermediate image that is subtracted from the second fluorescent image to reconstruct a background-subtracted image.
Abstract translation: 介绍了成像系统和方法。 该方法包括产生激发光，其被配置为在选择性地结合还包括背景物种的对象的感兴趣区域（ROI）中的靶物种的成像剂中诱导荧光。 选择第一和第二光谱区域，使得对应于目标的荧光和第一光谱区域中的背景物质之间的确定的差异与第二光谱区域中的相应差异不同。 从对应于第一和第二光谱区域的荧光产生第一和第二荧光图像。 此外，确定第一和第二荧光图像中背景物质的荧光比。 然后将第一荧光图像与所确定的比率相乘或分割，以产生从第二荧光图像中减去的中间图像，以重构背景相减的图像。
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公开(公告)号：US20150004641A1
公开(公告)日：2015-01-01
申请号：US13927807
申请日：2013-06-26
Applicant: General Electric Company
Inventor： Dmitry Vladimirovich Dylov , Juan Pablo Cilia , Victor Petrovich Ostroverkhov , Siavash Yazdanfar , Stephen B. Solomon
CPC classification number: G01N1/30 , A61B10/0233
Abstract: An apparatus for holding a biopsy collecting device is presented. The apparatus includes a base unit configured to receive the biopsy collecting device comprising at least a needle unit and an activator unit, wherein the needle unit comprises a biopsy specimen. The apparatus further includes a fastening unit disposed at a first end of the base unit and configured to fasten at least a first portion of the needle unit to the base unit. Also, the apparatus includes a holding unit disposed at a second end of the base unit and configured to attach the activator unit of the biopsy collecting device to the base unit.
Abstract translation: 提出了一种用于保持活检收集装置的装置。 所述装置包括基本单元，其被配置为接收包括至少针单元和活化单元的活检收集装置，其中所述针单元包括活检样本。 该装置还包括紧固单元，该紧固单元设置在基座单元的第一端，并被配置为将针单元的至少第一部分固定到基座单元。 此外，该装置还包括一个保持单元，该保持单元设置在基座单元的第二端，并被配置成将活检收集装置的活化单元附着到基座单元。
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Patent Agency Ranking
公开(公告)号：US20140171764A1
公开(公告)日：2014-06-19
申请号：US13713745
申请日：2012-12-13
Applicant: GENERAL ELECTRIC COMPANY
IPC: A61B5/00
CPC classification number: A61B5/0071 , A61B1/00009 , A61B1/043 , A61B1/0638 , A61B5/4893 , A61B5/6847 , A61B17/00 , A61B90/361 , A61B90/37 , A61B2090/373 , A61B2505/05 , A61B2576/02
Abstract: Systems and methods for imaging are presented. The method includes producing excitation light configured to induce fluorescence in an imaging agent that selectively binds to a target species in a region of interest (ROI) of a subject that also includes a background species. A first and a second spectral region are selected such that a determined difference between fluorescence corresponding to the target and the background species in the first spectral region differs from a corresponding difference in the second spectral region. First and second fluorescence images are generated from the fluorescence corresponding to the first and second spectral regions. Additionally, a fluorescence ratio for the background species in the first and second fluorescence image is determined. The first fluorescence image is then multiplied or divided with the determined ratio to generate an intermediate image that is subtracted from the second fluorescent image to reconstruct a background-subtracted image.
Abstract translation: 介绍了成像系统和方法。 该方法包括产生激发光，其被配置为在选择性地结合还包括背景物种的对象的感兴趣区域（ROI）中的靶物种的成像剂中诱导荧光。 选择第一和第二光谱区域，使得对应于目标的荧光和第一光谱区域中的背景物质之间的确定的差异与第二光谱区域中的相应差异不同。 从对应于第一和第二光谱区域的荧光产生第一和第二荧光图像。 此外，确定第一和第二荧光图像中背景物质的荧光比。 然后将第一荧光图像与所确定的比率相乘或分割，以产生从第二荧光图像中减去的中间图像，以重构背景相减的图像。
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7.发明申请公开(公告)号：US20130286400A1
公开(公告)日：2013-10-31
申请号：US13663069
申请日：2012-10-29
Applicant: GENERAL ELECTRIC COMPANY
IPC: G01B9/02
CPC classification number: G01B9/0209 , G01B9/04 , G01B11/0675 , G01N21/45 , G02B21/14
Abstract: Systems and methods described herein employ multiple phase-contrast images with various relative phase shifts between light diffracted by a sample and light not diffracted by the sample to produce a quantitative phase image. The produced quantitative phase image may have sufficient contrast for label-free auto-segmentation of cell bodies and nuclei.
Abstract translation: 本文描述的系统和方法使用多个相差图像，其在由样品衍射的光和不被样品衍射的光之间具有各种相对相移，以产生定量相位图像。 所产生的定量相图可能具有足够的对比度，用于细胞体和细胞核的无标记自动分割。
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公开(公告)号：US11286849B2
公开(公告)日：2022-03-29
申请号：US16000810
申请日：2018-06-05
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Bernard Patrick Bewlay , Waseem Ibrahim Faidi , Peter William Lorraine , Mohamed Ahmed Ali , Siavash Yazdanfar , Ying Fan , Edward James Nieters , David Mills , Nicole Jessica Tibbetts, Jr.
IPC: F02B77/04 , B08B3/12 , B08B7/02 , F01D25/00 , B08B9/032 , B08B3/08 , B08B3/04 , H01L21/67 , H01L21/02 , B08B3/10
Abstract: A cleaning system and method use an ultrasound probe, a coupling mechanism, and a controller to clean equipment of a vehicle system. The ultrasound probe enters into an engine. The ultrasound probe emits ultrasound pulses and the coupling mechanism provides an ultrasound coupling medium between the ultrasound probe and one or more components of the engine. The controller drives the ultrasound probe to deliver the ultrasound pulse through the coupling medium to a surface of the one or more components of the engine. The ultrasound probe delivers the ultrasound pulse to remove deposits from the one or more components of the engine.
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公开(公告)号：US20160220129A1
公开(公告)日：2016-08-04
申请号：US14614026
申请日：2015-02-04
Applicant: General Electric Company
Inventor： Victor Petrovich Ostroverkhov , Alberto Santamaria-Pang , Dmitry V. Dylov , Ali Can , Siavash Yazdanfar
CPC classification number: A61B5/0261 , A61B5/02007 , A61B5/6815 , A61B2562/0238 , A61B2576/00
Abstract: A method in one embodiment includes acquiring optical image information with a detection unit configured to be operably coupled to a patient. The optical image information corresponds to microcirculation of the patient. The method also includes generating a microcirculation map of microvasculature of the patient using the optical image information. Further, the method includes generating a quantitative microcirculation index based on the microcirculation map, the quantitative microcirculation index corresponding to a condition of the patient.
Abstract translation: 一个实施例中的方法包括采用被配置为可操作地耦合到患者的检测单元获取光学图像信息。 光学图像信息对应于患者的微循环。 该方法还包括使用光学图像信息产生患者的微血管微循环图。 此外，该方法包括基于微循环图生成与患者状况对应的定量微循环指标的定量微循环指标。
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公开(公告)号：US09216010B2
公开(公告)日：2015-12-22
申请号：US13927683
申请日：2013-06-26
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Victor Petrovich Ostroverkhov , Dmitry Vladimirovich Dylov , Siavash Yazdanfar , Stephen B. Solomon
CPC classification number: A61B10/02 , G01B11/002 , G01J3/00 , G01N21/31 , G01N21/65 , G01N2021/6417
Abstract: A spectroscopy system for auto-aligning a biopsy collecting device is presented. The spectroscopy system includes an illumination subsystem configured to emit an illumination light towards the biopsy collecting device, whereas the biopsy collecting device includes an activator unit and a needle unit and wherein the needle unit includes a cannula and a stylet having a biopsy specimen. Also, the spectroscopy system includes a fixation subsystem capable of holding the biopsy collecting device and configured to place the needle unit comprising the biopsy specimen across the illumination light. Further, the spectroscopy system includes a detection subsystem configured to receive a light comprising at least one of an attenuated illumination light and a re-emitted light from the needle unit. In addition, the detection subsystem is configured to send a control signal to align the needle unit at a predetermined position in the spectroscopy system based on the received light.
Abstract translation: 提出了一种用于自动对准活检收集装置的光谱系统。 光谱系统包括被配置为朝向活检收集装置发射照明光的照明子系统，而活检收集装置包括激活器单元和针单元，并且其中针单元包括插管和具有活检样本的探针。 此外，光谱系统包括固定子系统，其能够保持活检收集装置并且构造成将包括活检标本的针单元放置在照明光上。 此外，光谱系统包括被配置为接收包括衰减照明光和来自针单元的再发射光中的至少一种的光的检测子系统。 此外，检测子系统被配置为发送控制信号，以根据所接收的光将针单元对准在光谱系统中的预定位置。
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