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公开(公告)号：US12117397B2
公开(公告)日：2024-10-15
申请号：US17818637
申请日：2022-08-09
Applicant: GENEWAVE
Inventor： Claude Weisbuch , Lucio Martinelli , Henri Benisty , Christof Schafauer , Gabriel Sagarzazu , Thierry Gacoin , Mélanie Bedu
IPC: G01N21/64 , B01L3/00 , G01N21/47 , G01N21/77 , G02B5/00 , G02B5/02 , G02B6/124 , G02B6/14 , G02B6/42
CPC classification number: G01N21/6428 , B01L3/502715 , G01N21/47 , G01N21/6456 , G01N21/648 , G01N21/7703 , G02B5/00 , G02B5/02 , G02B5/0236 , G02B5/0257 , G02B6/124 , G02B6/14 , G02B6/42 , G02B6/4206 , B01L2300/0654 , B01L2300/0819 , B01L2300/168 , G01N21/77 , G01N2201/0634
Abstract: A biochip device includes a waveguide, chromophore elements, a diffusing structure, and a sloping surface. The chromophore elements are disposed on a portion of the waveguide and are configured to emit fluorescence in response to excitation by guided light waves transmitted by the waveguide. The diffusing structure is configured to generate guided light waves in the waveguide when illuminated. The sloping surface is sloped relative to a plane of the waveguide and is configured to direct excitation light into the waveguide, and the sloping surface and the waveguide are configured to deflect the excitation light to the diffusing structure to generate guided light waves within the waveguide. The sloping surface may be a face of a prism attached to or integrated with the waveguide, or the sloping surface may be a bevel formed at an edge of the waveguide.
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公开(公告)号：USRE46165E1
公开(公告)日：2016-09-27
申请号：US14799092
申请日：2015-07-14
Applicant: Genewave
Inventor： Claude Weisbuch
CPC classification number: G01N21/648 , G01N21/6458 , G01N21/7703 , G01N2021/6419 , G01N2021/6421 , G01N2021/6441 , G01N2021/6471 , G02B6/42
Abstract: A device for supporting chromophore elements suitable for emitting fluorescence in response to light excitation, the device comprising a substrate having a surface layer carrying the chromophore elements, forming a planar waveguide, and containing photoluminescent constituents which emit guided luminescence at the excitation wavelength(s) of the chromophore elements when they are excited by primary excitation light illuminating the surface layer. The invention is particularly applicable to biochip type devices.
Abstract translation: 一种用于支持适于发射响应于光激发的荧光的发色元件的装置，所述装置包括具有承载发色团元件的表面层的基底，形成平面波导，并且包含以激发波长发射引导发光的光致发光成分， 的发色团元素当它们被照射表面层的主激发光激发时。 本发明特别适用于生物芯片型装置。
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公开(公告)号：US11415514B2
公开(公告)日：2022-08-16
申请号：US16205256
申请日：2018-11-30
Applicant: GENEWAVE
Inventor： Claude Weisbuch , Lucio Martinelli , Henri Benisty , Christof Schafauer , Gabriel Sagarzazu , Thierry Gacoin , Mélanie Bedu
Abstract: A biochip device comprising a substrate constituted by at least one plate of material forming a multimode planar waveguide and carrying chromophore elements suitable for emitting fluorescence in response to excitation by guided waves having an evanescent portion, the device being characterized in that it includes coupling means for coupling excitation light with the waveguide in the form of guided waves, the coupling means being substantially non-directional.
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