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1.发明公开公开(公告)号：US20230183774A1
公开(公告)日：2023-06-15
申请号：US18064511
申请日：2022-12-12
CPC分类号： C12Q1/20 , G01N21/78 , B01L3/5085 , C12Q1/04 , B01L2300/0829 , B01L2300/0654
摘要： An exemplary embodiment of the present disclosure provides a system for detecting antimicrobial resistance of a bacteria in a biological sample. In some embodiments, the system can include a plurality of containers, a detecting agent in each of the plurality of containers, and an antimicrobial agent in at least a portion of the plurality of containers. The antimicrobial agent is disposed in at least one of the plurality of containers. Each of the containers can contain at least a portion of the biological sample. The detecting agent can be configured to produce optically detectable changes responsive to bacterial respiration or growth, directly from patient samples of from patient sample cultures.
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公开(公告)号：US20190338334A1
公开(公告)日：2019-11-07
申请号：US16477260
申请日：2018-01-12
IPC分类号： C12Q1/04 , G01N15/14 , G01N21/39 , G01N33/487 , C12Q1/18
摘要： The invention is directed to a method for rapidly determining antibiotic susceptibility in bodily fluid samples based on rigorous multidimensional statistical metrics. In some embodiments, the method incorporates flow cytometry to determine susceptibility. In preferred embodiments, the method is adapted for use with samples with low bacterial counts.
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公开(公告)号：US12061143B2
公开(公告)日：2024-08-13
申请号：US16477260
申请日：2018-01-12
CPC分类号： G01N15/1459 , C12Q1/18 , G01N21/39 , G01N2015/1006 , G01N2015/1402 , G01N2015/1488
摘要： The invention is directed to a method for rapidly determining antibiotic susceptibility in bodily fluid samples based on rigorous multidimensional statistical metrics. In some embodiments, the method incorporates flow cytometry to determine susceptibility. In preferred embodiments, the method is adapted for use with samples with low bacterial counts.
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