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    Immunity Adjuvant Containing a Complexed Metal Cation and Vaccine Containing Same
    1.
    发明申请
    Immunity Adjuvant Containing a Complexed Metal Cation and Vaccine Containing Same 审中-公开
    包含复合金属阳离子和含有其的疫苗的免疫佐剂

    公开(公告)号：US20080019989A1

    公开(公告)日：2008-01-24

    申请号：US11842560

    申请日：2007-08-21

    申请人： Gerard TROUVE ,  Laurent Dupuis

    发明人： Gerard TROUVE ,  Laurent Dupuis

    IPC分类号： A61K45/00 ,  B01F3/08

    CPC分类号： A61K39/39 ,  A61K9/0019 ,  A61K9/113 ,  A61K47/36 ,  A61K2039/55555 ,  Y02A50/41 ,  Y02A50/412

    摘要： The present invention relates to novel adjuvants for vaccine compositions and said compositions comprising at least one antigen, in particular an antigen of vital, bacterial or parasitic origin and at least one adjuvant. In particular, the subject of the invention is a composition comprising a fatty phase and a nonzero quantity of an organometallic gel comprising a complex of an anionic polymer, or a mixture of different anionic polymers, with a multivalent metal cation or a mixture of different multivalent metal cations.

    摘要翻译： 本发明涉及用于疫苗组合物的新型佐剂，所述组合物包含至少一种抗原，特别是重要的，细菌或寄生起源的抗原和至少一种佐剂。 特别地，本发明的主题是包含脂肪相和非零量的有机金属凝胶的组合物，其包含阴离子聚合物或不同阴离子聚合物的混合物与多价金属阳离子或不同多价的混合物 金属阳离子。

    METHOD FOR PREPARING A VACCINE COMPOSITION COMPRISING AT LEAST ONE ANTIGEN AND AT LEAST ONE ADJUVANT
    3.
    发明申请
    METHOD FOR PREPARING A VACCINE COMPOSITION COMPRISING AT LEAST ONE ANTIGEN AND AT LEAST ONE ADJUVANT 有权
    用于制备包含至少一种抗原和至少一种调节剂的疫苗组合物的方法

    公开(公告)号：US20100233196A1

    公开(公告)日：2010-09-16

    申请号：US12739389

    申请日：2008-10-06

    申请人： Laurent Dupuis ,  Olivier Braun

    发明人： Laurent Dupuis ,  Olivier Braun

    IPC分类号： A61K39/00 ,  A61P37/04

    CPC分类号： A61K9/127 ,  A61K9/0019 ,  A61K47/32 ,  A61K47/44

    摘要： Method for preparing a vaccine, comprising—a step a) of preparing an adjuvant composition by dispersing, in a physiologically acceptable aqueous solution, at least one inverse latex or a powder of polymer resulting from the atomization of said inverse latex; —a step b) of mixing the composition obtained in step a) into an antigenic medium, intended to form a vaccine composition.

    摘要翻译： 制备疫苗的方法，包括：a）通过在生理上可接受的水溶液中分散至少一种反相胶乳或由所述反相胶乳的雾化产生的聚合物粉末来制备佐剂组合物; - 步骤b）将步骤a）中获得的组合物混合到用于形成疫苗组合物的抗原介质中。

    ADJUVANT FOR THE PREPARATION OF VACCINE COMPOSITIONS INTENDED FOR THE PREVENTION OF COCCIDIOSIS
    5.
    发明申请
    ADJUVANT FOR THE PREPARATION OF VACCINE COMPOSITIONS INTENDED FOR THE PREVENTION OF COCCIDIOSIS 有权
    适用于预防预防结核病的疫苗组合物的准备

    公开(公告)号：US20120308604A1

    公开(公告)日：2012-12-06

    申请号：US13575971

    申请日：2011-01-14

    申请人： Laurent Dupuis ,  Francois Bertrand ,  Sebastien Deville

    发明人： Laurent Dupuis ,  Francois Bertrand ,  Sebastien Deville

    IPC分类号： A61K47/06 ,  A61P33/02 ,  A61K39/012

    CPC分类号： A61K39/39 ,  A61K39/012 ,  A61K2039/552 ,  A61K2039/55566 ,  A61K2039/57

    摘要： A vaccine adjuvant which, based on the 100% mass thereof, includes between 10% and 95% of a mineral oil containing: between 0.05 mass-% and 10 mass-% hydrocarbon chains having less than 16 carbon atoms, and between 0.05 mass-% and 5 mass-% hydrocarbon chains having more than 28 carbon atoms. In addition, the adjuvant has a P/N ratio, corresponding to the ratio of the mass quantity of the paraffinic hydrocarbon chains to the mass quantity of the naphthenic hydrocarbon chains, of between 2.5 and 3, the adjuvant being intended for the production of a vaccine composition to prevent coccidiosis.

    摘要翻译： 基于其100％质量的疫苗佐剂包含10％至95％的矿物油，其含有0.05质量％至10质量％的碳原子数小于16的烃链和0.05质量％ 具有大于28个碳原子的％和5质量％烃链。 此外，佐剂对应于石蜡烃链的质量与环烷烃链的质量之比的P / N比在2.5和3之间，所述佐剂用于生产 疫苗组合物以预防球虫病。

    Adjuvant for the preparation of vaccine compositions intended for the prevention of coccidiosis
    6.
    发明授权
    Adjuvant for the preparation of vaccine compositions intended for the prevention of coccidiosis 有权
    用于制备旨在预防球虫病的疫苗组合物的佐剂

    公开(公告)号：US08703154B2

    公开(公告)日：2014-04-22

    申请号：US13575971

    申请日：2011-01-14

    申请人： Laurent Dupuis ,  Francois Bertrand ,  Sebastien Deville

    发明人： Laurent Dupuis ,  Francois Bertrand ,  Sebastien Deville

    IPC分类号： A61K39/39 ,  A61K39/012

    CPC分类号： A61K39/39 ,  A61K39/012 ,  A61K2039/552 ,  A61K2039/55566 ,  A61K2039/57

    摘要： A vaccine adjuvant which, based on the 100% mass thereof, includes between 10% and 95% of a mineral oil containing: between 0.05 mass-% and 10 mass-% hydrocarbon chains having less than 16 carbon atoms, and between 0.05 mass-% and 5 mass-% hydrocarbon chains having more than 28 carbon atoms. In addition, the adjuvant has a P/N ratio, corresponding to the ratio of the mass quantity of the paraffinic hydrocarbon chains to the mass quantity of the naphthenic hydrocarbon chains, of between 2.5 and 3, the adjuvant being intended for the production of a vaccine composition to prevent coccidiosis.

    摘要翻译： 基于其100％质量的疫苗佐剂包含10％至95％的矿物油，其含有0.05质量％至10质量％的碳原子数小于16的烃链和0.05质量％ 具有大于28个碳原子的％和5质量％烃链。 此外，佐剂对应于石蜡烃链的质量与环烷烃链的质量之比的P / N比在2.5和3之间，所述佐剂用于生产 疫苗组合物以预防球虫病。

    ADJUVANT DILUENTS FOR LIVE VACCINES FOR PIG DISEASES
    7.
    发明申请
    ADJUVANT DILUENTS FOR LIVE VACCINES FOR PIG DISEASES 审中-公开
    用于皮肤疾病的活疫苗的补充剂

    公开(公告)号：US20130011434A1

    公开(公告)日：2013-01-10

    申请号：US13636741

    申请日：2011-03-15

    申请人： Francois Bertrand ,  Sebastien Deville ,  Laurent Dupuis

    发明人： Francois Bertrand ,  Sebastien Deville ,  Laurent Dupuis

    IPC分类号： A61K39/12 ,  A61P31/14 ,  A61P37/04

    CPC分类号： A61K39/12 ,  A61K2039/5254 ,  A61K2039/552 ,  A61K2039/55555 ,  A61K2039/55566 ,  C12N2770/10034 ,  C12N2770/10051

    摘要： A method for preparing an injectable vaccine composition intended to combat porcine reproductive and respiratory syndrome (PRRS), includes at least the step in which: a) a live vaccine is mixed extemporaneously with an adjuvant diluent (AD). The adjuvant diluent is an oil-in-water-type emulsion or an oil-in-water-type microemulsion, or an aqueous solution including water and at least one inorganic salt selected from aluminum hydroxide, cerium nitrate, zinc sulfate, colloidal iron hydroxide or calcium chloride, salts of divalent or trivalent metals or sympathomimetic compounds.

    摘要翻译： 制备旨在对抗猪繁殖与呼吸综合征（PRRS）的可注射疫苗组合物的方法至少包括以下步骤：a）活疫苗与佐剂稀释剂（AD）同时混合。 助剂稀释剂是水包油型乳剂或水包油型微乳液，或水包括水和至少一种选自氢氧化铝，硝酸铈，硫酸锌，胶态氢氧化铁的无机盐的水溶液 或氯化钙，二价或三价金属或拟交替物质的盐。

    Communication by carrier current for centralized control centers
    9.
    发明申请
    Communication by carrier current for centralized control centers 审中-公开
    通过运营商电流进行集中控制中心的通信

    公开(公告)号：US20080316005A1

    公开(公告)日：2008-12-25

    申请号：US12155799

    申请日：2008-06-10

    申请人： Olivier Coutelou ,  Erick Contini ,  Laurent Dupuis

    发明人： Olivier Coutelou ,  Erick Contini ,  Laurent Dupuis

    IPC分类号： G05B11/01

    CPC分类号： H04B3/54 ,  H04B2203/5425 ,  H04B2203/5458

    摘要： In an intelligent centralized control panel, in particular for motors in which case it is known under the name of iMCC, communications with the outside are performed by powerline carrier current or PLC. The wiring of the control panels can thereby be greatly reduced. To enable this type of communication to be used in dense systems containing a large number of line starters and therefore a large number of parallel-connected carrier current interfaces, the invention proposes inserting a preferably electronically adjustable impedance in series with the PLC conversion device. Advantageously, an adjustment algorithm enables the values of the added impedances to be optimized according to the geometry and position of the different interfaces.

    摘要翻译： 在智能集中控制面板中，特别是对于电机，在这种情况下，以iMCC为名称，电力线载波电流或PLC由外部进行通信。 因此可以大大减少控制面板的布线。 为了使这种类型的通信能够用在包含大量线路起动器的密集系统中，因此大量并联的载波电流接口，本发明提出了一种优选地电可调节的阻抗与PLC转换装置的串联插入。 有利地，调整算法使得可以根据不同接口的几何形状和位置来优化所添加的阻抗的值。