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公开(公告)号:US20070224198A1
公开(公告)日:2007-09-27
申请号:US11623496
申请日:2007-01-16
IPC分类号: A61K39/395
CPC分类号: C07K16/36 , A61K38/00 , A61K39/395 , A61K2039/505 , C07K16/40 , C07K2317/24 , C07K2317/76 , C07K2317/92 , A61K2300/00
摘要: Monoclonal antibodies directed against coagulation factors and their use in inhibiting thrombosis in combination with plasminogen activators are disclosed.
摘要翻译: 公开了针对凝血因子的单克隆抗体及其与纤维蛋白溶酶原激活剂联合用于抑制血栓形成的用途。
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公开(公告)号:US20070129415A1
公开(公告)日:2007-06-07
申请号:US11673605
申请日:2007-02-12
申请人: David BROOKS , Giora Feuerstein , Eliot Ohlstein , Robert Ruffolo
发明人: David BROOKS , Giora Feuerstein , Eliot Ohlstein , Robert Ruffolo
IPC分类号: A61K31/4178
CPC分类号: A61K31/415 , A61K31/4178
摘要: This invention relates to the use of eprosartan to treat isolated systolic hypertension.
摘要翻译: 本发明涉及依普罗沙坦治疗孤立性收缩期高血压的用途。
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3.Antioxidant cardioprotective use of, and method of treatment using, hydroxycarbazole compounds 失效
标题翻译: 抗氧化剂心脏保护用途及治疗方法使用羟基咔唑化合物公开(公告)号:US5405863A
公开(公告)日:1995-04-11
申请号:US128327
申请日:1993-09-28
申请人: Frank C. Barone , Giora Feuerstein , Tian-Li Yue
发明人: Frank C. Barone , Giora Feuerstein , Tian-Li Yue
IPC分类号: A61K31/40 , A61K31/403 , A61P43/00 , C07D209/86 , C07D209/88
CPC分类号: A61K31/40
摘要: This invention relates to a new antioxidant use of, and method of treatment using certain hydroxycarbazole compounds or a pharmaceutically acceptable salt thereof. More specifically, the compounds are useful for the prevention of oxidative tissue damage to organs, particularly the central nervous system including the brain, in mammals afflicted with disease-induced ischemic trauma, particularly stroke.
摘要翻译: 本发明涉及使用某些羟基咔唑化合物或其药学上可接受的盐的新型抗氧化剂用途和治疗方法。 更具体地说,这些化合物可用于在受到疾病诱发的缺血创伤,特别是中风的哺乳动物中,预防对器官,特别是包括脑的中枢神经系统的氧化组织损伤。
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公开(公告)号:US20060057140A1
公开(公告)日:2006-03-16
申请号:US11240195
申请日:2005-09-30
申请人: Giora Feuerstein
发明人: Giora Feuerstein
IPC分类号: A61K39/395
CPC分类号: C07K16/36 , A61K2039/505 , C07K16/40 , C07K2317/24
摘要: Monoclonal antibodies directed against coagulation factors and their use in inhibiting thrombosis are disclosed.
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公开(公告)号:US20070190059A1
公开(公告)日:2007-08-16
申请号:US11622623
申请日:2007-01-12
申请人: Frank Barone , Michael Blackburn , Giora Feuerstein , John Toomey
发明人: Frank Barone , Michael Blackburn , Giora Feuerstein , John Toomey
IPC分类号: A61K39/395
CPC分类号: C07K16/36 , A61K2039/505 , C07K2317/24 , C07K2317/76
摘要: Monoclonal antibodies directed against coagulation factor IX and their use in inhibiting thrombosis are disclosed.
摘要翻译: 公开了针对凝血因子IX的单克隆抗体及其在抑制血栓形成中的用途。
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公开(公告)号:US20050113431A1
公开(公告)日:2005-05-26
申请号:US11012041
申请日:2004-12-14
申请人: David Brooks , Giora Feuerstein , Eliot Ohlstein , Robert Ruffolo
发明人: David Brooks , Giora Feuerstein , Eliot Ohlstein , Robert Ruffolo
IPC分类号: A61K31/415 , A61K31/4178 , A61K31/4184
CPC分类号: A61K31/415 , A61K31/4178
摘要: This invention relates to the use of eprosartan to treat isolated systolic hypertension.
摘要翻译: 本发明涉及依普罗沙坦治疗孤立性收缩期高血压的用途。
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公开(公告)号:US20150125396A1
公开(公告)日:2015-05-07
申请号:US14296721
申请日:2014-06-05
申请人: Giora Feuerstein , Richard Cliff
发明人: Giora Feuerstein , Richard Cliff
IPC分类号: A61K49/00
CPC分类号: A61K49/0056 , A61B3/12 , A61B5/4088 , A61K49/0021 , A61K49/006 , G01N33/6896 , G01N2800/2821
摘要: Described are methods for the detection, in the eye of an individual, of protein aggregates or other misfolded proteins associated with disease using peptide or peptide mimic probes that preferentially associate with the protein aggregates or misfolded proteins, which can be accomplished non-invasively.
摘要翻译: 描述了在个体眼中检测蛋白质聚集体或与疾病相关的其他错误折叠的蛋白质的方法,其使用优先与蛋白质聚集体或错误折叠的蛋白质相关联的肽或肽模拟探针,其可非侵入性地完成。
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公开(公告)号:US20070003553A1
公开(公告)日:2007-01-04
申请号:US11201592
申请日:2005-08-11
申请人: Michael Blackburn , William Church , Giora Feuerstein , Mitchell Gross , Andrew Nichols , Eduardo Padlan , Arunbhai Patel , Daniel Sylvester
发明人: Michael Blackburn , William Church , Giora Feuerstein , Mitchell Gross , Andrew Nichols , Eduardo Padlan , Arunbhai Patel , Daniel Sylvester
IPC分类号: A61K39/395 , A61K31/60
CPC分类号: C07K16/36 , A61K38/00 , A61K39/395 , A61K2039/505 , C07K16/40 , C07K2317/24 , C07K2317/76 , C07K2317/92 , A61K2300/00
摘要: Chimeric, humanized and other IL-5 mAbs, derived from high affinity neutralizing mAbs, pharmaceutical compositions containing same, methods of treatment and diagnostics are provided.
摘要翻译: 提供衍生自高亲和力中和mAb的嵌合,人源化和其它IL-5mAb,含有其的药物组合物,治疗方法和诊断。
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公开(公告)号:US20050037006A1
公开(公告)日:2005-02-17
申请号:US10638777
申请日:2003-08-11
申请人: Frank Barone , Michael Blackburn , Giora Feuerstein , John Toomey
发明人: Frank Barone , Michael Blackburn , Giora Feuerstein , John Toomey
IPC分类号: A61K38/46 , A61K39/395 , A61P7/02 , C07K16/36 , C07K16/40
CPC分类号: C07K16/40 , A61K2039/505 , C07K16/36 , C07K2317/24
摘要: Monoclonal antibodies directed against coagulation factor IX and their use in inhibiting thrombosis are disclosed.
摘要翻译: 公开了针对凝血因子IX的单克隆抗体及其在抑制血栓形成中的用途。
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