-
1.Compounds and pharmaceutical combinations for the treatment of neurodegenerative and ischemic brain diseases 有权
标题翻译: 用于治疗神经变性和缺血性脑疾病的化合物和药物组合公开(公告)号:US09518085B2
公开(公告)日:2016-12-13
申请号:US14127369
申请日:2012-06-29
申请人: Giselle Penton Rol , Alexey Llopiz Arzuaga , Javier Marin Prida , Eduardo Penton Arias , Efrain Rodriguez Jimenez , Alexis Musacchio Lasa , Vladimir Armando Besada Perez , Gilberto Lazaro Pardo Andreu , Luis Javier Gonzalez Lopez , Nancy Pavon Fuentes , Gerardo Enrique Guillen Nieto , Pedro Antonio Lopez Saura
发明人: Giselle Penton Rol , Alexey Llopiz Arzuaga , Javier Marin Prida , Eduardo Penton Arias , Efrain Rodriguez Jimenez , Alexis Musacchio Lasa , Vladimir Armando Besada Perez , Gilberto Lazaro Pardo Andreu , Luis Javier Gonzalez Lopez , Nancy Pavon Fuentes , Gerardo Enrique Guillen Nieto , Pedro Antonio Lopez Saura
IPC分类号: C07K7/06 , C07K5/08 , A61K38/00 , C07K5/10 , C07K5/083 , C07K5/103 , A61K38/06 , A61K38/07 , A61K38/18 , A61K38/20 , A61K38/21 , A61K38/25 , A61K38/08
CPC分类号: A61K31/409 , A61K38/00 , A61K38/06 , A61K38/07 , A61K38/08 , A61K38/1816 , A61K38/2013 , A61K38/21 , A61K38/212 , A61K38/215 , A61K38/25 , A61K47/55 , C07K5/08 , C07K5/081 , C07K5/10 , C07K5/1008 , C07K7/06 , A61K2300/00 , A61K36/06
摘要: The present invention describes peptides comprising phycocyanobilin (PCB), as well as the medical use of said peptides and that of PCB, due to the neuroprotector and/or neuroregenerative effects identified for them. Furthermore, pharmaceutical combinations of said peptides and of PCB with proteins or other peptides with synergic effect justify their use for ischemic or neurodegenerative CNS disease treatment.
摘要翻译: 本发明描述了由于对其鉴定的神经保护剂和/或神经再生作用,包含珊瑚蓝菌素(PCB)的肽以及所述肽和PCB的医学用途。 此外,所述肽和PCB与具有协同作用的蛋白质或其他肽的药物组合证明其用于缺血性或神经退行性CNS疾病治疗。