公开(公告)号：US11466299B2

公开(公告)日：2022-10-11

申请号：US17240262

申请日：2021-04-26

Applicant: Givaudan SA

Inventor： Eric Eichhorn ,  Boris Schilling ,  Denis Wahler ,  Laurent Fourage ,  Esther Locher

IPC: C12P17/04 ,  C12N9/90 ,  C07D307/92

Abstract: There is provided SHC/HAC derivatives, amino acid sequences comprising the SHC/HAC derivatives, nucleotide sequences encoding the SHC/HAC derivatives, vectors comprising nucleotide sequences encoding the SHC/HAC derivatives, recombinant host cells comprising nucleotide sequences encoding the SHC/HAC derivatives and applications of the recombinant host cells comprising either SHC/HAC derivatives or WT SHC/HAC enzymes in methods to prepare (−)-Ambrox and SHC/HAC enzymes in methods to prepare (−)-Ambrox.

公开(公告)号：US12071645B2

公开(公告)日：2024-08-27

申请号：US17900590

申请日：2022-08-31

Applicant: Givaudan SA

Inventor： Eric Eichhorn ,  Boris Schilling ,  Denis Wahler ,  Laurent Fourage ,  Esther Locher

IPC: C12P17/04 ,  C07D307/92 ,  C12N9/90

CPC classification number: C12P17/04 ,  C07D307/92 ,  C12N9/90

Abstract: There is provided SHC/HAC derivatives, amino acid sequences comprising the SHC/HAC derivatives, nucleotide sequences encoding the SHC/HAC derivatives, vectors comprising nucleotide sequences encoding the SHC/HAC derivatives, recombinant host cells comprising nucleotide sequences encoding the SHC/HAC derivatives and applications of the recombinant host cells comprising either SHC/HAC derivatives or WT SHC/HAC enzymes in methods to prepare (−)-Ambrox and SHC/HAC enzymes in methods to prepare (−)-Ambrox.

公开(公告)号：US11021722B2

公开(公告)日：2021-06-01

申请号：US16598317

申请日：2019-10-10

Applicant: Givaudan SA

Inventor： Eric Eichhorn ,  Boris Schilling ,  Denis Wahler ,  Laurent Fourage ,  Esther Locher

IPC: C12P17/04 ,  C12N9/90 ,  C07D307/92

Abstract: There is provided SHC/HAC derivatives, amino acid sequences comprising the SHC/HAC derivatives, nucleotide sequences encoding the SHC/HAC derivatives, vectors comprising nucleotide sequences encoding the SHC/HAC derivatives, recombinant host cells comprising nucleotide sequences encoding the SHC/HAC derivatives and applications of the recombinant host cells comprising either SHC/HAC derivatives or WT SHC/HAC enzymes in methods to prepare (−)-Ambrox and SHC/HAC enzymes in methods to prepare (−)-Ambrox.

公开(公告)号：US11485985B2

公开(公告)日：2022-11-01

申请号：US16765649

申请日：2018-11-21

Applicant: Givaudan SA

Inventor： Andreas Goeke ,  Julie Charpentier ,  Boris Schilling ,  Fridtjof Schröder

IPC: C12P7/38 ,  A23L27/20 ,  A23L27/10 ,  C07C45/27 ,  C12N9/88

Abstract: A process for producing rotundone from α-guaiene, in particular by oxidation of the C(3) position, wherein the α-guaiene is produced from a precursor by a sesquiterpene synthase. The sesquiterpene synthase is produced in a microorganism.

公开(公告)号：US10472655B2

公开(公告)日：2019-11-12

申请号：US15568945

申请日：2016-04-22

Applicant: Givaudan SA

Inventor： Eric Eichhorn ,  Boris Schilling ,  Denis Wahler ,  Laurent Fourage ,  Esther Locher

IPC: C12P17/04 ,  C07D307/92 ,  C12N9/90

Abstract: There is provided SHC/HAC derivatives, amino acid sequences comprising the SHC/HAC derivatives, nucleotide sequences encoding the SHC/HAC derivatives, vectors comprising nucleotide sequences encoding the SHC/HAC derivatives, recombinant host cells comprising nucleotide sequences encoding the SHC/HAC derivatives and applications of the recombinant host cells comprising either SHC/HAC derivatives or WT SHC/HAC enzymes in methods to prepare (−)-Ambrox and SHC/HAC enzymes in methods to prepare (−)-Ambrox.