公开(公告)号：US11773419B2

公开(公告)日：2023-10-03

申请号：US17680840

申请日：2022-02-25

Applicant: Givaudan SA

Inventor： Ghislain Sanhaji ,  Alix Rousseaux ,  Sandrine Noel ,  Eric Eichhorn

IPC: C07D307/92 ,  C12P17/04 ,  A61Q13/00

CPC classification number: C12P17/04 ,  A61Q13/00 ,  C07D307/92 ,  C07B2200/07 ,  C07B2200/13 ,  C12Y504/99017

Abstract: A solid form of (−)-Ambrox formed by a bioconversion process.

公开(公告)号：US10472655B2

公开(公告)日：2019-11-12

申请号：US15568945

申请日：2016-04-22

Applicant: Givaudan SA

Inventor： Eric Eichhorn ,  Boris Schilling ,  Denis Wahler ,  Laurent Fourage ,  Esther Locher

IPC: C12P17/04 ,  C07D307/92 ,  C12N9/90

Abstract: There is provided SHC/HAC derivatives, amino acid sequences comprising the SHC/HAC derivatives, nucleotide sequences encoding the SHC/HAC derivatives, vectors comprising nucleotide sequences encoding the SHC/HAC derivatives, recombinant host cells comprising nucleotide sequences encoding the SHC/HAC derivatives and applications of the recombinant host cells comprising either SHC/HAC derivatives or WT SHC/HAC enzymes in methods to prepare (−)-Ambrox and SHC/HAC enzymes in methods to prepare (−)-Ambrox.

公开(公告)号：US12084699B2

公开(公告)日：2024-09-10

申请号：US18322167

申请日：2023-05-23

Applicant: Givaudan SA

Inventor： Ghislain Sanhaji ,  Alix Rousseaux ,  Sandrine Noel ,  Eric Eichhorn

IPC: C12P17/04 ,  A61Q13/00 ,  C07D307/92

CPC classification number: C12P17/04 ,  A61Q13/00 ,  C07D307/92 ,  C07B2200/07 ,  C07B2200/13 ,  C12Y504/99017

Abstract: A solid form of (−)-Ambrox formed by a bioconversion process.

公开(公告)号：US11965195B2

公开(公告)日：2024-04-23

申请号：US17777336

申请日：2020-12-03

Applicant: Givaudan SA

Inventor： Eric Eichhorn ,  Felix Flachsmann

IPC: C12P17/04 ,  C07C33/02 ,  C07D307/92

CPC classification number: C12P17/04 ,  C07C33/02 ,  C07D307/92 ,  C12Y504/99017

Abstract: An enzyme-mediated method for the production of 3a-ethyl-6,6,9a-trimethyldodecahydronaphtho[2,1-b]furan, the products of said method, and uses of said products.

公开(公告)号：US11466299B2

公开(公告)日：2022-10-11

申请号：US17240262

申请日：2021-04-26

Applicant: Givaudan SA

Inventor： Eric Eichhorn ,  Boris Schilling ,  Denis Wahler ,  Laurent Fourage ,  Esther Locher

IPC: C12P17/04 ,  C12N9/90 ,  C07D307/92

Abstract: There is provided SHC/HAC derivatives, amino acid sequences comprising the SHC/HAC derivatives, nucleotide sequences encoding the SHC/HAC derivatives, vectors comprising nucleotide sequences encoding the SHC/HAC derivatives, recombinant host cells comprising nucleotide sequences encoding the SHC/HAC derivatives and applications of the recombinant host cells comprising either SHC/HAC derivatives or WT SHC/HAC enzymes in methods to prepare (−)-Ambrox and SHC/HAC enzymes in methods to prepare (−)-Ambrox.

公开(公告)号：US12071645B2

公开(公告)日：2024-08-27

申请号：US17900590

申请日：2022-08-31

Applicant: Givaudan SA

Inventor： Eric Eichhorn ,  Boris Schilling ,  Denis Wahler ,  Laurent Fourage ,  Esther Locher

IPC: C12P17/04 ,  C07D307/92 ,  C12N9/90

CPC classification number: C12P17/04 ,  C07D307/92 ,  C12N9/90

Abstract: There is provided SHC/HAC derivatives, amino acid sequences comprising the SHC/HAC derivatives, nucleotide sequences encoding the SHC/HAC derivatives, vectors comprising nucleotide sequences encoding the SHC/HAC derivatives, recombinant host cells comprising nucleotide sequences encoding the SHC/HAC derivatives and applications of the recombinant host cells comprising either SHC/HAC derivatives or WT SHC/HAC enzymes in methods to prepare (−)-Ambrox and SHC/HAC enzymes in methods to prepare (−)-Ambrox.

公开(公告)号：US11965202B2

公开(公告)日：2024-04-23

申请号：US17427171

申请日：2020-02-26

Applicant: GIVAUDAN SA

Inventor： Felix Flachsmann ,  Eric Eichhorn

IPC: C12P7/02 ,  C12N9/90 ,  C12P7/26 ,  C12P7/62

CPC classification number: C12P7/62

Abstract: A method for making 2-oxygenated decalins, and products thereof.

公开(公告)号：US11021722B2

公开(公告)日：2021-06-01

申请号：US16598317

申请日：2019-10-10

Applicant: Givaudan SA

Inventor： Eric Eichhorn ,  Boris Schilling ,  Denis Wahler ,  Laurent Fourage ,  Esther Locher

IPC: C12P17/04 ,  C12N9/90 ,  C07D307/92

Abstract: There is provided SHC/HAC derivatives, amino acid sequences comprising the SHC/HAC derivatives, nucleotide sequences encoding the SHC/HAC derivatives, vectors comprising nucleotide sequences encoding the SHC/HAC derivatives, recombinant host cells comprising nucleotide sequences encoding the SHC/HAC derivatives and applications of the recombinant host cells comprising either SHC/HAC derivatives or WT SHC/HAC enzymes in methods to prepare (−)-Ambrox and SHC/HAC enzymes in methods to prepare (−)-Ambrox.

公开(公告)号：US10294211B2

公开(公告)日：2019-05-21

申请号：US15568535

申请日：2016-04-22

Applicant: Givaudan SA

Inventor： Eric Eichhorn

IPC: C07D307/92 ,  C12P17/04 ,  C11B9/00 ,  B01D9/00 ,  C07B63/00

Abstract: A method of isolating and purifying (−)-Ambrox from a reaction mixture comprising (−)-Ambrox and one or more of the compounds (II), (III) and (IV)