公开(公告)号：US10457674B2

公开(公告)日：2019-10-29

申请号：US16073355

申请日：2017-02-10

Applicant: GlaxoSmithKline Intellectual Property Development Limited

Inventor： Niall Andrew Anderson ,  Nicholas Paul Barton ,  Sebastien Andre Campos ,  Edward Paul Cannons ,  Anthony William James Cooper ,  Kenneth David Down ,  Kevin James Doyle ,  Julie Nicole Hamblin ,  Graham George Adam Inglis ,  Armelle Le Gall ,  Vipulkumar Kantibhai Patel ,  Simon Peace ,  Andrew Sharpe ,  Gemma Victoria White

IPC: C07D413/14 ,  C07D213/76 ,  A61P25/28 ,  A61P11/06 ,  A61P37/08 ,  A61P25/24 ,  A61P15/08

Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular PI3-kinase activity.

公开(公告)号：US10793559B2

公开(公告)日：2020-10-06

申请号：US16572917

申请日：2019-09-17

Applicant: GlaxoSmithKline Intellectual Property Development Limited

Inventor： Niall Andrew Anderson ,  Nicholas Paul Barton ,  Sebastien Andre Campos ,  Edward Paul Cannons ,  Anthony William James Cooper ,  Kenneth David Down ,  Kevin James Doyle ,  Julie Nicole Hamblin ,  Graham George Adam Inglis ,  Armelle Le Gall ,  Vipulkumar Kantibhai Patel ,  Simon Peace ,  Andrew Sharpe ,  Gemma Victoria White

IPC: C07D413/14 ,  C07D213/76 ,  A61P25/28 ,  A61P11/06 ,  A61P37/08 ,  A61P25/24 ,  A61P15/08

Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular PI3-kinase activity.