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公开(公告)号:US10450312B2
公开(公告)日:2019-10-22
申请号:US16007584
申请日:2018-06-13
Inventor: Niall Andrew Anderson , Brendan John Fallon , John Martin Pritchard
IPC: C07D471/04 , A61P11/00
Abstract: A compound of formula (I) or a salt thereof wherein R1 represents a hydrogen atom, a methyl group or a ethyl group R2 represents a hydrogen atom or a fluorine atom R3 represents a hydrogen atom, a methyl group or an ethyl group.
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公开(公告)号:US20170290817A1
公开(公告)日:2017-10-12
申请号:US15514399
申请日:2015-09-22
Inventor: Niall Andrew Anderson , Matthew Howard James Campbell-Crawford , Ashley Paul Hancock , John Martin Pritchard , Joanna Mary Redmond
IPC: A61K31/4375 , C07D471/04
CPC classification number: A61K31/4375 , A61K31/19 , C07D471/04
Abstract: A compound of formula (I): which is 4-(3-fluoro-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)-3-(3-(2-methoxyethoxy)phenyl)butanoic acid, or a salt thereof.
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公开(公告)号:US10342783B2
公开(公告)日:2019-07-09
申请号:US15922674
申请日:2018-03-15
Inventor: Niall Andrew Anderson , Matthew Howard James Campbell-Crawford , Ashley Paul Hancock , John Martin Pritchard , Joanna Mary Redmond
IPC: A61K31/4375 , C07D471/04 , A61K31/19
Abstract: A compound of formula (I): being 4-(3-Fluoro-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl) ethyl) pyrrolidin-1-yl)-3-(3-(2-methoxyethoxy) phenyl) butanoic acid, or a salt thereof.
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公开(公告)号:US10023568B2
公开(公告)日:2018-07-17
申请号:US14778095
申请日:2014-03-26
Inventor: Niall Andrew Anderson , Brendan John Fallon , John Martin Pritchard
IPC: C07D471/04
Abstract: A compound of formula (I) or a salt thereof wherein R1 represents a hydrogen atom, a methyl group or a ethyl group R2 represents a hydrogen atom or a fluorine atom R3 represents a hydrogen atom, a methyl group or an ethyl group.
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5.NAPHTHYRIDINE DERIVATIVES USEFUL AS ALPHA-V-BETA-6 INTEGRIN ANTAGONISTS 有权
Title translation: 适用于ALPHA-V-BETA-6 INTEGRIN ANTAGONISTS的萘啶衍生物公开(公告)号:US20160280705A1
公开(公告)日:2016-09-29
申请号:US14778095
申请日:2014-03-26
Inventor: Niall Andrew Anderson , Brendan John Fallon , John Martin Pritchard
IPC: C07D471/04
CPC classification number: C07D471/04 , A61P11/00
Abstract: A compound of formula (I) or a salt thereof wherein R1 represents a hydrogen atom, a methyl group or a ethyl group R2 represents a hydrogen atom or a fluorine atom R3 represents a hydrogen atom, a methyl group or an ethyl group.
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公开(公告)号:US11485710B2
公开(公告)日:2022-11-01
申请号:US17156478
申请日:2021-01-22
Inventor: Niall Andrew Anderson , Deepak Bandyopadhyay , Alain Claude-Marie Daugan , Frederic G. Donche , Patrick M. Eidam , Nicolas Eric Faucher , Nicolas S. George , Philip Anthony Harris , Jae U. Jeong , Bryan W. King , Clark A. Sehon , Gemma Victoria White , David Duff Wisnoski
IPC: A61K31/415 , C07D231/06 , C07D401/14 , C07D405/14 , C07D413/14 , C07D401/04 , C07D401/06 , C07D405/04 , C07D405/06 , C07D409/14 , C07D417/14 , C07D403/04 , C07D487/04 , A61P21/00 , A61K31/422 , A61K31/454 , A61K31/4545 , A61K31/506 , A61K31/5377 , C07D403/06 , C07D409/06 , C07D413/04
Abstract: Disclosed are compounds having the formula: wherein R1, R2, and R3 are as defined herein, and methods of making and using the same.
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公开(公告)号:US20210253532A1
公开(公告)日:2021-08-19
申请号:US17156478
申请日:2021-01-22
Inventor: Niall Andrew Anderson , Deepak Bandyopadhyay , Alain Claude-Marie Daugan , Frederic G. Donche , Patrick M. Eidam , Nicolas Eric Faucher , Nicolas S. George , Philip Anthony Harris , Jae U. Jeong , Bryan W. King , Clark A. Sehon , Gemma Victoria White , David Duff Wisnoski
IPC: C07D231/06 , C07D401/14 , C07D405/14 , C07D413/14 , C07D401/04 , C07D401/06 , C07D405/04 , C07D405/06 , C07D409/14 , C07D417/14 , C07D403/04 , C07D487/04 , A61P21/00 , A61K31/415 , A61K31/422 , A61K31/454 , A61K31/4545 , A61K31/506 , A61K31/5377 , C07D403/06 , C07D409/06 , C07D413/04
Abstract: Disclosed are compounds having the formula: wherein R1, R2, and R3 are as defined herein, and methods of making and using the same.
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公开(公告)号:US10899716B2
公开(公告)日:2021-01-26
申请号:US16778206
申请日:2020-01-31
Inventor: Niall Andrew Anderson , Deepak Bandyopadhyay , Alain Claude-Marie Daugan , Frederic G. Donche , Patrick M. Eidam , Nicolas Eric Faucher , Nicolas S. George , Philip Anthony Harris , Jae U. Jeong , Bryan W. King , Clark A. Sehon , Gemma Victoria White , David Duff Wisnoski
IPC: A61K31/4439 , C07D401/06 , C07D231/06 , C07D401/14 , C07D405/14 , C07D413/14 , C07D401/04 , C07D405/04 , C07D405/06 , C07D409/14 , C07D417/14 , C07D403/04 , C07D487/04 , A61P21/00 , A61K31/415 , A61K31/422 , A61K31/454 , A61K31/4545 , A61K31/506 , A61K31/5377 , C07D403/06 , C07D409/06 , C07D413/04
Abstract: Disclosed are compounds having the formula: wherein R1, R2, and R3 are as defined herein, and methods of making and using the same.
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公开(公告)号:US10457674B2
公开(公告)日:2019-10-29
申请号:US16073355
申请日:2017-02-10
Inventor: Niall Andrew Anderson , Nicholas Paul Barton , Sebastien Andre Campos , Edward Paul Cannons , Anthony William James Cooper , Kenneth David Down , Kevin James Doyle , Julie Nicole Hamblin , Graham George Adam Inglis , Armelle Le Gall , Vipulkumar Kantibhai Patel , Simon Peace , Andrew Sharpe , Gemma Victoria White
IPC: C07D413/14 , C07D213/76 , A61P25/28 , A61P11/06 , A61P37/08 , A61P25/24 , A61P15/08
Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular PI3-kinase activity.
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公开(公告)号:US20230120185A1
公开(公告)日:2023-04-20
申请号:US17935791
申请日:2022-09-27
Inventor: Niall Andrew Anderson , Deepak Bandyopadhyay , Alain Daugan , Frederic G. Donche , Patrick M. Eidam , Nicolas Eric Faucher , Nicolas S. George , Philip Anthony Harris , Jae U. Jeong , Bryan W. King , Clark A. Sehon , Gemma Victoria White , David Duff Wisnoski
IPC: C07D231/06 , C07D401/14 , C07D405/14 , C07D413/14 , C07D401/04 , C07D401/06 , C07D405/04 , C07D405/06 , C07D409/14 , C07D417/14 , C07D403/04 , C07D487/04 , A61P21/00 , A61K31/415 , A61K31/422 , A61K31/454 , A61K31/4545 , A61K31/506 , A61K31/5377 , C07D403/06 , C07D409/06 , C07D413/04
Abstract: Disclosed are compounds having the formula: wherein R1, R2, and R3 are as defined herein, and methods of making and using the same.
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