公开(公告)号：US20240228503A1

公开(公告)日：2024-07-11

申请号：US18586620

申请日：2024-02-26

Applicant: GlaxoSmithKline Intellectual Property Development Limited

Inventor： Adam K. CHARNLEY ,  Janos BOTYANSZKI ,  Xiaoyang DONG ,  Philip Gareth HUMPHREYS ,  Bryan Wayne KING ,  Kimberly Katherine MARCUS ,  Joseph PERO ,  Alexander Joseph REIF ,  Daohua ZHANG ,  Attiq RAHMAN(Deceased) ,  Kenneth Allen NEWLANDER ,  Kenneth WIGGALL ,  Joshi RAMANJULU

IPC: C07D487/04 ,  C07D403/14 ,  C07D471/04 ,  C07D471/14 ,  C07F9/6561

CPC classification number: C07D487/04 ,  C07D403/14 ,  C07D471/04 ,  C07D471/14 ,  C07F9/6561

Abstract: The present invention relates to compounds, compositions containing them, and to their use in the treatment of various disorders, in particular autoimmune, autoinflammatory or immune-mediated conditions, such as systemic lupus erythematosus (SLE), cutaneous lupus erythematosus (CLE) and lupus nephritis.