公开(公告)号：US20160060222A1

公开(公告)日：2016-03-03

申请号：US14934395

申请日：2015-11-06

Applicant: GlaxoSmithKline Intellectual Property Development Limited

Inventor： Michael Jonathan BURY ,  Linda N. CASILLAS ,  Adam Kenneth CHARNLEY ,  Michael P. DeMARTINO ,  Xiaoyang DONG ,  Patrick EIDAM ,  Pamela A. HAILE ,  Philip Anthony HARRIS ,  Ami Lakdawala SHAH ,  Bryan W. KING ,  Robert W. MARQUIS, JR. ,  John F. MEHLMANN ,  Joseph J. ROMANO ,  Clark A. SEHON

IPC: C07D215/42 ,  C07D215/44 ,  C07D401/12 ,  C07D405/12 ,  C07D411/12 ,  C07D215/48 ,  C07D471/04 ,  C07D417/14 ,  C07D513/04 ,  C07D405/14 ,  C07D401/14 ,  C07D417/12 ,  C07D413/12

CPC classification number: C07D215/42 ,  A61K31/47 ,  C07D215/44 ,  C07D215/48 ,  C07D401/12 ,  C07D401/14 ,  C07D405/12 ,  C07D405/14 ,  C07D411/12 ,  C07D413/12 ,  C07D417/12 ,  C07D417/14 ,  C07D471/04 ,  C07D513/04

Abstract: Disclosed are quinoline compounds having the formula: wherein R1, R2 and A are as defined herein, and methods of making and using the same.