公开(公告)号：US20200165205A1

公开(公告)日：2020-05-28

申请号：US16778206

申请日：2020-01-31

Applicant: GlaxoSmithKline Intellectual Property Development Limited

Inventor： Niall Andrew ANDERSON ,  Deepak BANDYOPADHYAY ,  Alain Claude-Marie DAUGAN ,  Frederic G. DONCHE ,  Patrick M. EIDAM ,  Nicolas Eric FAUCHER ,  Nicolas S. GEORGE ,  Philip Anthony HARRIS ,  Jae U. JEONG ,  Bryan W. KING ,  Clark A. SEHON ,  Gemma Victoria WHITE ,  David Duff WISNOSKI

IPC: C07D231/06 ,  C07D413/04 ,  C07D409/06 ,  C07D403/06 ,  A61K31/5377 ,  A61K31/506 ,  A61K31/4545 ,  A61K31/454 ,  A61K31/422 ,  A61K31/415 ,  A61P21/00 ,  C07D417/14 ,  C07D409/14 ,  C07D405/06 ,  C07D405/04 ,  C07D401/06 ,  C07D401/04 ,  C07D413/14 ,  C07D405/14 ,  C07D401/14 ,  C07D487/04 ,  C07D403/04

Abstract: Disclosed are compounds having the formula: wherein R1, R2, and R3 are as defined herein, and methods of making and using the same.

公开(公告)号：US20180134665A1

公开(公告)日：2018-05-17

申请号：US15575235

申请日：2016-05-19

Applicant: GlaxoSmithKline Intellectual Property Development Limited

Inventor： Niall Andrew ANDERSON ,  Deepak BANDYOPADHYAY ,  Alain Claude-Marie DAUGAN ,  Frederic G. DONCHE ,  Patrick M. EIDAM ,  Nicolas Eric FAUCHER ,  Nicolas S. GEORGE ,  Philip Anthony HARRIS ,  Jae U. JEONG ,  Bryan W. KING ,  Clark A. SEHON ,  Gemma Victoria WHITE ,  David Duff WISNOSKI

IPC: C07D231/06 ,  C07D401/14 ,  A61K31/506 ,  A61K31/4545 ,  C07D405/14 ,  A61K31/454 ,  A61K31/415 ,  C07D401/04 ,  C07D401/06 ,  C07D403/06 ,  C07D405/06 ,  C07D413/04 ,  A61K31/422 ,  C07D405/04 ,  C07D413/14 ,  A61K31/5377 ,  C07D417/14 ,  C07D409/14 ,  C07D409/06 ,  A61P21/00

CPC classification number: C07D231/06 ,  A61K31/415 ,  A61K31/422 ,  A61K31/454 ,  A61K31/4545 ,  A61K31/506 ,  A61K31/5377 ,  A61P21/00 ,  C07D401/04 ,  C07D401/06 ,  C07D401/14 ,  C07D403/04 ,  C07D403/06 ,  C07D405/04 ,  C07D405/06 ,  C07D405/14 ,  C07D409/06 ,  C07D409/14 ,  C07D413/04 ,  C07D413/14 ,  C07D417/14 ,  C07D487/04

Abstract: Disclosed are compounds having the formula (I): wherein R1, R2, and R3 are as defined herein, and methods of making and using the same.

公开(公告)号：US20160060222A1

公开(公告)日：2016-03-03

申请号：US14934395

申请日：2015-11-06

Applicant: GlaxoSmithKline Intellectual Property Development Limited

Inventor： Michael Jonathan BURY ,  Linda N. CASILLAS ,  Adam Kenneth CHARNLEY ,  Michael P. DeMARTINO ,  Xiaoyang DONG ,  Patrick EIDAM ,  Pamela A. HAILE ,  Philip Anthony HARRIS ,  Ami Lakdawala SHAH ,  Bryan W. KING ,  Robert W. MARQUIS, JR. ,  John F. MEHLMANN ,  Joseph J. ROMANO ,  Clark A. SEHON

IPC: C07D215/42 ,  C07D215/44 ,  C07D401/12 ,  C07D405/12 ,  C07D411/12 ,  C07D215/48 ,  C07D471/04 ,  C07D417/14 ,  C07D513/04 ,  C07D405/14 ,  C07D401/14 ,  C07D417/12 ,  C07D413/12

CPC classification number: C07D215/42 ,  A61K31/47 ,  C07D215/44 ,  C07D215/48 ,  C07D401/12 ,  C07D401/14 ,  C07D405/12 ,  C07D405/14 ,  C07D411/12 ,  C07D413/12 ,  C07D417/12 ,  C07D417/14 ,  C07D471/04 ,  C07D513/04

Abstract: Disclosed are quinoline compounds having the formula: wherein R1, R2 and A are as defined herein, and methods of making and using the same.