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公开(公告)号：US20180222982A1
公开(公告)日：2018-08-09
申请号：US15747873
申请日：2016-07-28
申请人： Glenn Dranoff , Gordon James Freeman , Arlene Helen Sharpe , Walter A. Blattler , Jennifer Marie Mataraza , Catherine Anne Sabatos-Peyton , Hwai Wen Chang , Gerhard Johann Frey , Novartis AG , DANA-FARBER CANCER INSTITUTE, INC. , PRESIDENT AND FELLOWS OF HARVARD COLLEGE
发明人： Glenn Dranoff , Gordon James Freeman , Arlene Helen Sharpe , Walter A. Blattler , Jennifer Marie Mataraza , Catherine Anne Sabatos-Peyton , Hwai Wen Chang , Gerhard Johann Frey
IPC分类号： C07K16/28 , A61P35/00 , A61K39/395
CPC分类号： C07K16/2818 , A61K39/00 , A61K39/39541 , A61K2039/505 , A61P35/00 , C07K2317/24 , C07K2317/56 , C07K2317/76 , C07K2317/92
摘要： Combination therapies comprising antibody molecules that specifically bind to PD-1 disclosed. The combination therapies can be used to treat or prevent cancerous or infectious conditions and disorders.
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公开(公告)号：US20180207273A1
公开(公告)日：2018-07-26
申请号：US15747326
申请日：2016-07-28
申请人： Glenn Dranoff , Catherine Anne Sabatos-Peyton , Barbara Brannetti , Alan S. Harris , Thomas Huber , Thomas Pietzonka , Jennifer Marie Mataraza , Walter A. Blattler , Daniel J. Hicklin , Maximiliano Vasquez , Rosemarie H. DeKruyff , Dale T. Umetsu , Gordon James Freeman , Tiancen Hu , John A. Taraszka , Fangmin Xu , Novartis AG , DANA-FARBER CANCER INSTITUTE, INC. , Children's Medical Center Corporation
发明人： Glenn Dranoff , Catherine Anne Sabatos-Peyton , Barbara Brannetti , Alan S. Harris , Thomas Huber , Thomas Pietzonka , Jennifer Marie Mataraza , Walter A. Blattler , Daniel J. Hicklin , Maximiliano Vasquez , Rosemarie H. DeKruyff , Dale T. Umetsu , Gordon James Freeman , Tiancen Hu , John A. Taraszka , Fangmin Xu
IPC分类号： A61K39/395 , A61K45/06 , A61P35/00
CPC分类号： A61K39/39566 , A61K39/00 , A61K39/3955 , A61K45/06 , A61K2039/507 , A61P35/00 , C07K16/2803 , C07K2299/00 , C07K2317/24 , C07K2317/34 , C07K2317/76 , C07K2317/94 , A61K2300/00
摘要： Combination therapies comprising antibody molecules that specifically bind to TIM-3 are disclosed. The combination therapies can be used to treat or prevent cancerous or infectious conditions and disorders.
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公开(公告)号：US11827704B2
公开(公告)日：2023-11-28
申请号：US16925980
申请日：2020-07-10
发明人： Gordon James Freeman , Arlene Helen Sharpe , Walter A. Blattler , Jennifer Marie Mataraza , Catherine Anne Sabatos-Peyton , Hwai Wen Chang , Gerhard Johann Frey
IPC分类号： G01N33/574 , C07K16/28 , G01N33/566 , G01N33/68 , A61K45/06 , C07K16/30
CPC分类号： C07K16/2818 , A61K45/06 , C07K16/2896 , C07K16/30 , G01N33/566 , G01N33/57484 , G01N33/6854 , C07K2317/24 , C07K2317/31 , C07K2317/565 , C07K2317/569 , C07K2317/74 , C07K2317/76 , C07K2317/92 , G01N2333/70596 , Y02A50/30
摘要： Antibody molecules that specifically bind to PD-1 are disclosed. The anti-PD-1 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious conditions and disorders.
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公开(公告)号：US20150210769A1
公开(公告)日：2015-07-30
申请号：US14604415
申请日：2015-01-23
发明人： Gordon James Freeman , Arlene Helen Sharpe , Walter A. Blattler , Jennifer Marie Mataraza , Catherine Anne Sabatos-Peyton , Hwai Wen Chang , Gerhard Johann Frey
IPC分类号： C07K16/28 , G01N33/574 , A61K39/395
CPC分类号： C07K16/2818 , A61K39/3955 , A61K45/06 , C07K16/2896 , C07K2317/24 , C07K2317/31 , C07K2317/565 , C07K2317/569 , C07K2317/74 , C07K2317/76 , C07K2317/92 , G01N33/566 , G01N33/57484 , G01N33/6854 , G01N2333/70596 , Y02A50/58
摘要： Antibody molecules that specifically bind to PD-1 are disclosed. The anti-PD-1 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious conditions and disorders.
摘要翻译： 公开了特异性结合PD-1的抗体分子。 抗PD-1抗体分子可用于治疗，预防和/或诊断癌性或感染性疾病和病症。
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公开(公告)号：US09683048B2
公开(公告)日：2017-06-20
申请号：US14604415
申请日：2015-01-23
发明人： Gordon James Freeman , Arlene Helen Sharpe , Walter A. Blattler , Jennifer Marie Mataraza , Catherine Anne Sabatos-Peyton , Hwai Wen Chang , Gerhard Johann Frey
IPC分类号： A61K39/395 , C07K16/28 , G01N33/574 , G01N33/566 , G01N33/68 , A61K45/06
CPC分类号： C07K16/2818 , A61K39/3955 , A61K45/06 , C07K16/2896 , C07K2317/24 , C07K2317/31 , C07K2317/565 , C07K2317/569 , C07K2317/74 , C07K2317/76 , C07K2317/92 , G01N33/566 , G01N33/57484 , G01N33/6854 , G01N2333/70596 , Y02A50/58
摘要： Antibody molecules that specifically bind to PD-1 are disclosed. The anti-PD-1 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious conditions and disorders.
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公开(公告)号：US10752687B2
公开(公告)日：2020-08-25
申请号：US15727456
申请日：2017-10-06
发明人： Gordon James Freeman , Arlene Helen Sharpe , Walter A. Blattler , Jennifer Marie Mataraza , Catherine Anne Sabatos-Peyton , Hwai Wen Chang , Gerhard Johann Frey
IPC分类号： C07K16/28 , C07K16/30 , G01N33/566 , G01N33/68 , A61K45/06 , G01N33/574
摘要： Antibody molecules that specifically bind to PD-1 are disclosed. The anti-PD-1 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious conditions and disorders.
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公开(公告)号：US20180155427A1
公开(公告)日：2018-06-07
申请号：US15727456
申请日：2017-10-06
发明人： Gordon James Freeman , Arlene Helen Sharpe , Walter A. Blattler , Jennifer Marie Mataraza , Catherine Anne Sabatos-Peyton , Hwai Wen Chang , Gerhard Johann Frey
IPC分类号： C07K16/28
摘要： Antibody molecules that specifically bind to PD-1 are disclosed. The anti-PD-1 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious conditions and disorders.
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公开(公告)号：US09815898B2
公开(公告)日：2017-11-14
申请号：US15595618
申请日：2017-05-15
发明人： Gordon James Freeman , Arlene Helen Sharpe , Walter A. Blattler , Jennifer Marie Mataraza , Catherine Anne Sabatos-Peyton , Hwai Wen Chang , Gerhard Johann Frey
IPC分类号： C07K16/28
CPC分类号： C07K16/2818 , A61K39/3955 , A61K45/06 , C07K16/2896 , C07K2317/24 , C07K2317/31 , C07K2317/565 , C07K2317/569 , C07K2317/74 , C07K2317/76 , C07K2317/92 , G01N33/566 , G01N33/57484 , G01N33/6854 , G01N2333/70596 , Y02A50/58
摘要： Antibody molecules that specifically bind to PD-1 are disclosed. The anti-PD-1 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious conditions and disorders.
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公开(公告)号：US20170247456A1
公开(公告)日：2017-08-31
申请号：US15595618
申请日：2017-05-15
发明人： Gordon James Freeman , Arlene Helen Sharpe , Walter A. Blattler , Jennifer Marie Mataraza , Catherine Anne Sabatos-Peyton , Hwai Wen Chang , Gerhard Johann Frey
IPC分类号： C07K16/28
CPC分类号： C07K16/2818 , A61K39/3955 , A61K45/06 , C07K16/2896 , C07K2317/24 , C07K2317/31 , C07K2317/565 , C07K2317/569 , C07K2317/74 , C07K2317/76 , C07K2317/92 , G01N33/566 , G01N33/57484 , G01N33/6854 , G01N2333/70596 , Y02A50/58
摘要： Antibody molecules that specifically bind to PD-1 are disclosed. The anti-PD-1 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious conditions and disorders.
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公开(公告)号：US20230013364A1
公开(公告)日：2023-01-19
申请号：US17549586
申请日：2021-12-13
发明人： Glenn Dranoff , Gordon James Freeman , Arlene Helen Sharpe , Walter A. Blattler , Jennifer Marie Mataraza , Catherine Anne Sabatos-Peyton , Hwai Wen Chang , Gerhard Johann Frey
IPC分类号： C07K16/28 , A61K39/00 , A61P35/00 , A61K39/395
摘要： Combination therapies comprising antibody molecules that specifically bind to PD-1 are disclosed. The combination therapies can be used to treat or prevent cancerous or infectious conditions and disorders.
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