公开(公告)号：US10415021B2

公开(公告)日：2019-09-17

申请号：US15521580

申请日：2015-10-23

Applicant: Glycom A/S

Inventor： Elise Champion ,  Andreas Vogel ,  Sebastian Bartsch ,  Gyula Dekany

IPC: C12N9/26 ,  C12N15/00 ,  C12P19/18 ,  C07H21/04 ,  C12P21/06 ,  C12P21/04 ,  C12N9/10 ,  C12N9/24 ,  C12P19/04

Abstract: Mutated fucosidases are provided demonstrating improved properties in terms of thermal stability and transfucosidase synthetic performance compared with a wild type transfucosidase isolated from Bifidobacterium longum subsp. infantis.

公开(公告)号：US10428318B2

公开(公告)日：2019-10-01

申请号：US15579843

申请日：2016-06-09

Applicant: Glycom A/S

Inventor： Andreas Vogel ,  Ramona Schmiedel ,  Elise Champion ,  Gyula Dekany

IPC: C12N9/10 ,  C12P21/00 ,  C07H3/06 ,  C12P19/18 ,  C12P19/04

Abstract: The invention provides engineered enzymes of transsialidase and/or sialyl transferase activity that have increased regioselectivity and/or increased thermostability.