公开(公告)号：US10906043B2

公开(公告)日：2021-02-02

申请号：US14759815

申请日：2014-01-13

申请人： Gong Zhang ,  Francis Lin ,  Edward Stewart Richmond ,  Marshall Ring

发明人： Gong Zhang ,  Francis Lin ,  Edward Stewart Richmond ,  Marshall Ring

IPC分类号： B01L3/00 ,  G01N33/543 ,  G01N21/64 ,  B01L7/00 ,  C12Q1/686

摘要： A portable microfluidic system capable of rapid diagnosis is described, which is able to analyze genetic, protein and cell composition of a sample in parallel for specific diseases from a relatively small sample. The method uses a single microfluidic chip integrated into a unique portable microfluidic platform and provides improved diagnostic accuracy, allows for frequent monitoring and is suitable for easy use in clinical settings.

公开(公告)号：US20170001196A1

公开(公告)日：2017-01-05

申请号：US14759815

申请日：2014-01-13

申请人： Gong Zhang ,  Francis Lin ,  Edward Stewart Richmond ,  Marshall Ring

发明人： Gong Zhang ,  Francis Lin ,  Edward Stewart Richmond ,  Marshall Ring

IPC分类号： B01L3/00 ,  G01N33/543 ,  G01N21/64 ,  C12Q1/68

CPC分类号： B01L3/502761 ,  B01L3/502715 ,  B01L3/502738 ,  B01L3/502746 ,  B01L3/502753 ,  B01L7/52 ,  B01L2200/10 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/0861 ,  B01L2300/0864 ,  B01L2300/0887 ,  B01L2300/18 ,  B01L2400/0406 ,  B01L2400/0457 ,  B01L2400/084 ,  B01L2400/086 ,  C12Q1/686 ,  G01N21/6428 ,  G01N21/645 ,  G01N33/54366 ,  G01N2021/6439 ,  G01N2021/6482 ,  G01N2201/0627

摘要： A portable microfluidic system capable of rapid diagnosis is described, which is able to analyze genetic, protein and cell composition of a sample in parallel for specific diseases from a relatively small sample. The method uses a single microfluidic chip integrated into a unique portable microfluidic platform and provides improved diagnostic accuracy, allows for frequent monitoring and is suitable for easy use in clinical settings.

摘要翻译： 描述了能够快速诊断的便携式微流体系统，其能够从相对较小的样品分析特定疾病的平行的样品的遗传，蛋白质和细胞组成。 该方法使用集成到独特的便携式微流体平台中的单个微流控芯片，并提供改进的诊断准确性，允许频繁监测，并且适合于在临床环境中使用。

公开(公告)号：US20180146869A1

公开(公告)日：2018-05-31

申请号：US13825225

申请日：2011-09-20

申请人： Michael ZHANG ,  Zhaopeng Fan ,  Marshall Ring ,  Sara Korosch ,  David Keenan ,  Gerald Lefevre

发明人： Michael ZHANG ,  Zhaopeng Fan ,  Marshall Ring ,  Sara Korosch ,  David Keenan ,  Gerald Lefevre

IPC分类号： A61B5/024 ,  A61B5/02 ,  A61B5/00 ,  A61B5/1455

CPC分类号： A61B5/02416 ,  A61B5/02007 ,  A61B5/1455 ,  A61B5/6826 ,  A61B5/7264

摘要： The arterial health of an individual can be determined by: attaching a fingertip photopiethysmography device to a fingertip of the hand of the elevated arm of the individual; measuring the analog pulse contour of the individual using the fingertip photopiethysmography device; digitizing the analog pulse contour; analyzing the digitized pulse contour for stable waveforms; processing the stable waveforms of the digitized pulse contour using dynamic time warping; comparing the stable waveforms to a library of known disease state waveforms; and assigning a most probable disease state for the individual based on said comparison.

公开(公告)号：US10881309B2

公开(公告)日：2021-01-05

申请号：US13825225

申请日：2011-09-20

申请人： Michael Zhang ,  Zhaopeng Fan ,  Marshall Ring ,  Sara Korosch ,  David Keenan ,  Gerald Lefevre

发明人： Michael Zhang ,  Zhaopeng Fan ,  Marshall Ring ,  Sara Korosch ,  David Keenan ,  Gerald Lefevre

IPC分类号： A61B5/024 ,  A61B5/02 ,  A61B5/1455 ,  A61B5/00 ,  G16H50/20

摘要： The arterial health of an individual can be determined by: attaching a fingertip photopiethysmography device to a fingertip of the hand of the elevated arm of the individual; measuring the analog pulse contour of the individual using the fingertip photopiethysmography device; digitizing the analog pulse contour; analyzing the digitized pulse contour for stable waveforms; processing the stable waveforms of the digitized pulse contour using dynamic time warping; comparing the stable waveforms to a library of known disease state waveforms; and assigning a most probable disease state for the individual based on said comparison.