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    FAR-FIELD SENSING CHANNEL FOR IMPLANTABLE CARDIAC DEVICE
    1.
    发明申请
    FAR-FIELD SENSING CHANNEL FOR IMPLANTABLE CARDIAC DEVICE 有权
    用于可植入心脏装置的前置感测通道

    公开(公告)号：US20110295136A1

    公开(公告)日：2011-12-01

    申请号：US13205387

    申请日：2011-08-08

    申请人： Greg Zhang ,  Douglas R. Daum ,  James O. Gilkerson ,  Quan Ni

    发明人： Greg Zhang ,  Douglas R. Daum ,  James O. Gilkerson ,  Quan Ni

    IPC分类号： A61N1/365 ,  A61B5/0452 ,  A61N1/37

    CPC分类号： A61N1/371 ,  A61N1/3621 ,  A61N1/3756

    摘要： An implantable pacemaker is provided with a far-field sensing channel which requires a reduced refractory period during the time when pacing pulses are delivered as compared with sensing channels using intra-cardiac electrodes. The far-field sensing channel may use the conductive housing of the implantable device or can and an indifferent electrode mounted on the device header as the electrodes for its differential inputs. Such a far-field sensing channel is able to sense activity occurring in either the atria or the ventricles for the purposes of arrhythmia detection and/or capture verification.

    摘要翻译： 植入式心脏起搏器设置有远场感测通道，与使用心脏内电极的感测通道相比，在进行起搏脉冲的时间期间需要减少的不应期。 远场感测通道可以使用可植入装置的导电外壳或者可以将安装在设备头上的无关电极用作其差分输入的电极。 为了心律失常检测和/或捕获验证的目的，这种远场感测通道能够感测在心房或心室中发生的活动。

    Far-field sensing channel for implantable cardiac device
    2.
    发明授权
    Far-field sensing channel for implantable cardiac device 有权
    用于可植入心脏装置的远场感测通道

    公开(公告)号：US08224445B2

    公开(公告)日：2012-07-17

    申请号：US13205387

    申请日：2011-08-08

    申请人： Geng Zhang ,  Douglas R. Daum ,  James O. Gilkerson ,  Quan Ni

    发明人： Geng Zhang ,  Douglas R. Daum ,  James O. Gilkerson ,  Quan Ni

    IPC分类号： A61N1/37

    CPC分类号： A61N1/371 ,  A61N1/3621 ,  A61N1/3756

    摘要： An implantable pacemaker is provided with a far-field sensing channel which requires a reduced refractory period during the time when pacing pulses are delivered as compared with sensing channels using intra-cardiac electrodes. The far-field sensing channel may use the conductive housing of the implantable device or can and an indifferent electrode mounted on the device header as the electrodes for its differential inputs. Such a far-field sensing channel is able to sense activity occurring in either the atria or the ventricles for the purposes of arrhythmia detection and/or capture verification.

    摘要翻译： 植入式心脏起搏器设置有远场感测通道，与使用心脏内电极的感测通道相比，在进行起搏脉冲的时间期间需要减少的不应期。 远场感测通道可以使用可植入装置的导电外壳或者可以将安装在设备头上的无关电极用作其差分输入的电极。 为了心律失常检测和/或捕获验证的目的，这种远场感测通道能够感测在心房或心室中发生的活动。

    Far-field sensing channel for implantable cardiac device
    3.
    发明授权
    Far-field sensing channel for implantable cardiac device 有权
    用于可植入心脏装置的远场感测通道

    公开(公告)号：US07996083B2

    公开(公告)日：2011-08-09

    申请号：US10858848

    申请日：2004-06-02

    申请人： Geng Zhang ,  Douglas R. Daum ,  James O. Gilkerson ,  Quan Ni

    发明人： Geng Zhang ,  Douglas R. Daum ,  James O. Gilkerson ,  Quan Ni

    IPC分类号： A61N1/368

    CPC分类号： A61N1/371 ,  A61N1/3621 ,  A61N1/3756

    摘要： An implantable pacemaker is provided with a far-field sensing channel which requires a reduced refractory period during the time when pacing pulses are delivered as compared with sensing channels using intra-cardiac electrodes. The far-field sensing channel may use the conductive housing of the implantable device or can and an indifferent electrode mounted on the device header as the electrodes for its differential inputs. Such a far-field sensing channel is able to sense activity occurring in either the atria or the ventricles for the purposes of arrhythmia detection and/or capture verification.

    摘要翻译： 植入式心脏起搏器设置有远场感测通道，与使用心脏内电极的感测通道相比，在进行起搏脉冲的时间期间需要减少的不应期。 远场感测通道可以使用可植入装置的导电外壳或者可以将安装在设备头上的无关电极用作其差分输入的电极。 为了心律失常检测和/或捕获验证的目的，这种远场感测通道能够感测在心房或心室中发生的活动。

    WIRELESS ECG IN IMPLANTABLE DEVICES
    6.
    发明申请
    WIRELESS ECG IN IMPLANTABLE DEVICES 有权
    无线心电图在可植入的设备

    公开(公告)号：US20130046195A1

    公开(公告)日：2013-02-21

    申请号：US13657224

    申请日：2012-10-22

    申请人： Aaron R. McCabe ,  Avram Scheiner ,  Geng Zhang ,  Quan Ni ,  Douglas R. Daum ,  Yi Zhang

    发明人： Aaron R. McCabe ,  Avram Scheiner ,  Geng Zhang ,  Quan Ni ,  Douglas R. Daum ,  Yi Zhang

    IPC分类号： A61B5/0408

    CPC分类号： A61B5/0402 ,  A61N1/365 ,  A61N1/3756

    摘要： An implantable medical device such as an implantable pacemaker or implantable cardioverter/defibrillator includes a programmable sensing circuit providing for sensing of a signal approximating a surface electrocardiogram (ECG) through implanted electrodes. With various electrode configurations, signals approximating various standard surface ECG signals are acquired without the need for attaching electrodes with cables onto the skin. The various electrode configurations include, but are not limited to, various combinations of intracardiac pacing electrodes, portions of the implantable medical device contacting tissue, and electrodes incorporated onto the surface of the implantable medical device.

    摘要翻译： 诸如可植入起搏器或植入式心律转复/除颤器的可植入医疗装置包括可编程感测电路，用于通过植入电极感测接近表面心电图（ECG）的信号。 通过各种电极配置，获取近似各种标准表面ECG信号的信号，而不需要将电极与电缆连接在皮肤上。 各种电极配置包括但不限于心脏内起搏电极，可植入医疗器械接触组织的部分和结合到可植入医疗装置的表面上的电极的各种组合。

    WIRELESS ECG IN IMPLANTABLE DEVICES
    7.
    发明申请
    WIRELESS ECG IN IMPLANTABLE DEVICES 有权
    无线心电图在可植入的设备

    公开(公告)号：US20120053474A1

    公开(公告)日：2012-03-01

    申请号：US13288105

    申请日：2011-11-03

    申请人： Aaron McCabe ,  Avram Scheiner ,  Geng Zhang ,  Quan Ni ,  Douglas R. Daum ,  Yi Zhang

    发明人： Aaron McCabe ,  Avram Scheiner ,  Geng Zhang ,  Quan Ni ,  Douglas R. Daum ,  Yi Zhang

    IPC分类号： A61B5/0452 ,  A61N1/365

    CPC分类号： A61B5/0402 ,  A61N1/365 ,  A61N1/3756

    摘要： An implantable medical device such as an implantable pacemaker or implantable cardioverter/defibrillator includes a programmable sensing circuit providing for sensing of a signal approximating a surface electrocardiogram (ECG) through implanted electrodes. With various electrode configurations, signals approximating various standard surface ECG signals are acquired without the need for attaching electrodes with cables onto the skin. The various electrode configurations include, but are not limited to, various combinations of intracardiac pacing electrodes, portions of the implantable medical device contacting tissue, and electrodes incorporated onto the surface of the implantable medical device.

    摘要翻译： 诸如可植入起搏器或植入式心律转复/除颤器的可植入医疗装置包括可编程感测电路，用于通过植入电极感测接近表面心电图（ECG）的信号。 通过各种电极配置，获取近似各种标准表面ECG信号的信号，而不需要将电极与电缆连接在皮肤上。 各种电极配置包括但不限于心脏内起搏电极，可植入医疗器械接触组织的部分和结合到可植入医疗器械表面上的电极的各种组合。

    Calibration of adaptive-rate pacing using intrinsic chronotropic response
    8.
    发明授权
    Calibration of adaptive-rate pacing using intrinsic chronotropic response 有权
    使用固有变时响应校准自适应速率起搏

    公开(公告)号：US07974708B2

    公开(公告)日：2011-07-05

    申请号：US12565358

    申请日：2009-09-23

    申请人： Douglas R. Daum ,  Quan Ni

    发明人： Douglas R. Daum ,  Quan Ni

    IPC分类号： A61N1/365

    CPC分类号： A61N1/365

    摘要： Calibration of adaptive-rate pacing by a cardiac rhythm management system using an intrinsic chronotropic response. The cardiac rhythm management system may include an adaptive-rate pacing device. The adaptive-rate pacing device may include an adaptive-rate sensor module for measuring an activity level of the individual. A monitor module may be coupled to the adaptive-rate sensor module, the monitor module monitoring an intrinsic chronotropic response. A calculator module may be coupled to the monitor module, the calculator module calculating a calibrated parameter for the adaptive-rate pacing device based on the intrinsic chronotropic response. An adjuster module may be coupled to the calculator module, wherein the adjuster module adjusts the adaptive-rate pacing device based on the calibrated parameter. The parameters of the adaptive-rate pacing device adjusted by the adjuster module may include a sensor rate target, a maximum sensor rate, and a response factor.

    摘要翻译： 使用内在的时间延迟响应通过心律管理系统校准自适应起搏。 心律管理系统可以包括自适应速率起搏装置。 自适应速率起搏装置可以包括用于测量个人的活动水平的自适应速率传感器模块。 监视器模块可以耦合到自适应速率传感器模块，监视器模块监视固有的时间变化响应。 计算器模块可以耦合到监视器模块，计算器模块基于固有的时间变化响应来计算自适应速率起搏装置的校准参数。 调节器模块可以耦合到计算器模块，其中调节器模块基于校准参数来调整自适应速率起搏装置。 由调节器模块调整的自适应速率起搏装置的参数可以包括传感器速率目标，最大传感器速率和响应因子。

    CLOSED LOOP IMPEDANCE-BASED CARDIAC RESYNCHRONIZATION THERAPY SYSTEMS, DEVICES, AND METHODS
    9.
    发明申请
    CLOSED LOOP IMPEDANCE-BASED CARDIAC RESYNCHRONIZATION THERAPY SYSTEMS, DEVICES, AND METHODS 有权
    基于闭环阻塞的心脏再生治疗系统，装置和方法

    公开(公告)号：US20090048637A1

    公开(公告)日：2009-02-19

    申请号：US12254631

    申请日：2008-10-20

    申请人： Quan Ni ,  Jiang Ding ,  Yinghong Yu ,  Douglas R. Daum ,  Julio C. Spinelli ,  Jeffrey E. Stahmann

    发明人： Quan Ni ,  Jiang Ding ,  Yinghong Yu ,  Douglas R. Daum ,  Julio C. Spinelli ,  Jeffrey E. Stahmann

    IPC分类号： A61N1/365

    CPC分类号： A61N1/3627 ,  A61B5/053 ,  A61N1/36521 ,  A61N1/3682 ,  A61N1/3684

    摘要： This document discusses, among other things, systems, devices, and methods measure an impedance and, in response, adjust an atrioventricular (AV) delay or other cardiac resynchronization therapy (CRT) parameter that synchronizes left and right ventricular contractions. A first example uses parameterizes a first ventricular volume against a second ventricular volume during a cardiac cycle, using a loop area to create a synchronization fraction (SF). The CRT parameter is adjusted in closed-loop fashion to increase the SF. A second example measures a septal-freewall phase difference (PD), and adjusts a CRT parameter to decrease the PD. A third example measures a peak-to-peak volume or maximum rate of change in ventricular volume, and adjusts a CRT parameter to increase the peak-to-peak volume or maximum rate of change in the ventricular volume.

    摘要翻译： 本文件还讨论了系统，设备和方法测量阻抗，并作为响应调整房室（AV）延迟或同步左心室收缩和右心室收缩的其他心脏再同步治疗（CRT）参数。 第一个例子是使用循环区域创建同步分数（SF），在心动周期中使用第一心室容积对第二心室容积进行参数化。 CRT参数以闭环方式调整以增加SF。 第二个例子是测量隔层相位差（PD），并调整CRT参数以减少PD。 第三个例子测量峰 - 峰体积或最大心室容积变化率，并调整CRT参数以增加心室容积的峰 - 峰体积或最大变化率。

    Calibration of adaptive-rate pacing using intrinsic chronotropic response
    10.
    发明授权
    Calibration of adaptive-rate pacing using intrinsic chronotropic response 有权

    公开(公告)号：US07050854B2

    公开(公告)日：2006-05-23

    申请号：US10178277

    申请日：2002-06-24

    申请人： Douglas R. Daum ,  Quan Ni

    发明人： Douglas R. Daum ,  Quan Ni

    IPC分类号： A61N1/365

    CPC分类号： A61N1/365

    摘要： Calibration of adaptive-rate pacing by a cardiac rhythm management system using an intrinsic chronotropic response. The cardiac rhythm management system may include an adaptive-rate pacing device. The adaptive-rate pacing device may include an adaptive-rate sensor module for measuring an activity level of the individual. A monitor module may be coupled to the adaptive-rate sensor module, the monitor module monitoring an intrinsic chronotropic response. A calculator module may be coupled to the monitor module, the calculator module calculating a calibrated parameter for the adaptive-rate pacing device based on the intrinsic chronotropic response. An adjuster module may be coupled to the calculator module, wherein the adjuster module adjusts the adaptive-rate pacing device based on the calibrated parameter. The parameters of the adaptive-rate pacing device adjusted by the adjuster module may include a sensor rate target, a maximum sensor rate, and a response factor.