公开(公告)号：US20080073817A1

公开(公告)日：2008-03-27

申请号：US11748387

申请日：2007-05-14

申请人： Gregory Hyde ,  Jane Sifuentes ,  Kim Hayenga ,  Erik Eli ,  Jim Phelan ,  Ellen Roche

发明人： Gregory Hyde ,  Jane Sifuentes ,  Kim Hayenga ,  Erik Eli ,  Jim Phelan ,  Ellen Roche

IPC分类号： B29C53/80 ,  C08F216/06

CPC分类号： B29C53/42 ,  B29C33/52 ,  B29C39/006 ,  B29C39/34 ,  B29L2031/7532

摘要： Embodiments provide for partially cured, preformed pieces of PVA capable of later being formed into more specific models. The partially cured, pre-made pieces of PVA can take on many forms and shapes. For example, the shape may be a flat, tubular, cone, spherical, or other similar shape. In fact, more complex shapes such as full organs are also contemplated herein. Nevertheless, such pre-molded components are considered common or general shaped in that the particular shape is produced using standard or common molds, and then later formed into a more specific or desired shape. As such, the preformed pieces of PVA are only partially cured or cross-linked such that they can later be formed into the more specific models that then have additional processing (e.g., freeze-thaw cycle) to retain the new shape.

摘要翻译： 实施例提供了可以稍后形成更具体的模型的部分固化的预成型的PVA片。 PVA的部分固化预制件可以具有许多形式和形状。 例如，该形状可以是扁平的，管状的，锥形的，球形的或其它类似的形状。 事实上，这里也考虑了更复杂的形状，例如全器官。 然而，这样的预成型部件被认为是普通的或一般的形状，因为特定的形状是使用标准的或共同的模具制造的，然后形成更具体或期望的形状。 因此，预成型的PVA片仅部分固化或交联，使得它们可以随后形成更具体的模型，然后具有额外的加工（例如冻融循环）以保持新的形状。

公开(公告)号：US20080076101A1

公开(公告)日：2008-03-27

申请号：US11748374

申请日：2007-05-14

申请人： Gregory Hyde ,  Jane Sifuentes ,  Kim Hayenga ,  Erik Eli ,  Jim Phelan ,  Ellen Roche

发明人： Gregory Hyde ,  Jane Sifuentes ,  Kim Hayenga ,  Erik Eli ,  Jim Phelan ,  Ellen Roche

IPC分类号： G09B23/30 ,  B28B7/34 ,  B29D31/505

CPC分类号： G09B23/30

摘要： Anatomical models are provided with simulated plaque, lesion, chronic total occlusion, as well as other vascular diseases that more accurately replicate these abnormalities. In such embodiment, the vascular disease may be formed separate from the structured anatomical model. The formed vascular disease material may then be bonded to or within a PVA material in a separate process from forming this simulated vascular disease, thus providing a replicated specific anatomy structure with an abnormality for demonstrating, testing, and/or developing medical functions and/or devices.

摘要翻译： 解剖模型提供模拟斑块，病变，慢性完全闭塞，以及更准确地复制这些异常的其他血管疾病。 在这样的实施例中，血管疾病可以与结构解剖模型分开形成。 形成的血管疾病材料然后可以在单独的过程中与PVA材料结合或在PVA材料内形成该模拟的血管疾病，从而提供具有用于展示，测试和/或开发医学功能的异常的复制的特定解剖结构和/或 设备。

公开(公告)号：US20100049304A1

公开(公告)日：2010-02-25

申请号：US12580459

申请日：2009-10-16

申请人： Anton Clifford ,  Jeff Pappas ,  Erik Eli

发明人： Anton Clifford ,  Jeff Pappas ,  Erik Eli

IPC分类号： A61F2/06

CPC分类号： A61F2/91 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2210/0076 ,  A61F2220/0041 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2230/0054 ,  A61F2250/0031 ,  A61F2250/0098

摘要： Endoprosthesis, such as a stent, includes at least one annular element defined by a first set of strut members interconnected to define apices proximate opposite sides of the annular element. The annular element further includes a foot extension extending between at least one pair of circumferentially-adjacent strut members. The foot extension has first and second foot portions extending circumferentially from corresponding ends of the circumferentially-adjacent strut members, and are contoured to provide at least two areas of flexure. The first and second foot portions are joined at a toe portion of the foot extension, and define a circumferentially-directed apex between the pair of circumferentially-adjacent strut members. Preferably, at least one or more additional annular elements, each defined by interconnected strut members, are provided. The annular elements are generally expandable between a delivery configuration and a deployed configuration. The annular elements are longitudinally aligned and connected at connection locations with connectors, wherein at least one of the connectors is constructed of a bio-absorbable material.

摘要翻译： 内置假体，例如支架，包括至少一个环形元件，所述至少一个环形元件由第一组支柱构件限定，所述第一组撑杆构件互相连接以限定靠近所述环形元件相对侧的顶点。 环形元件还包括在至少一对周向相邻的支柱构件之间延伸的脚延伸部。 脚部延伸部具有从周向相邻的支柱构件的对应端部周向延伸的第一和第二脚部，并且具有轮廓以提供至少两个弯曲区域。 第一和第二脚部在脚延伸部的脚趾部分处连接，并且在一对周向相邻的支柱构件之间限定圆周方向的顶点。 优选地，提供至少一个或多个另外的环形元件，每个环形元件由互连的支柱构件限定。 环形元件通常在输送配置和展开配置之间可扩展。 环形元件在与连接器的连接位置处纵向对准并连接，其中至少一个连接器由生物吸收材料构成。

公开(公告)号：US07559947B2

公开(公告)日：2009-07-14

申请号：US11535529

申请日：2006-09-27

申请人： David Lowe ,  Erik Eli ,  Jeff Pappas ,  Howard H. Huang ,  Anton G. Clifford ,  Kevin Kang

发明人： David Lowe ,  Erik Eli ,  Jeff Pappas ,  Howard H. Huang ,  Anton G. Clifford ,  Kevin Kang

IPC分类号： A61F2/06

CPC分类号： A61F2/91 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2210/0076 ,  A61F2230/0043 ,  A61F2230/0054

摘要： Endoprosthesis, such as a stent, includes at least one annular element defined by a first set of strut members interconnected to define apices proximate opposite sides of the annular element. The annular element further includes a foot extension extending between at least one pair of circumferentially-adjacent strut members. The foot extension has first and second foot portions extending circumferentially from corresponding ends of the circumferentially-adjacent strut members, and are contoured to provide at least two areas of flexure. The first and second foot portions are joined at a toe portion of the foot extension, and define a circumferentially-directed apex between the pair of circumferentially-adjacent strut members. Preferably, at least one or more additional annular elements, each defined by interconnected strut members, are provided. The annular elements are generally expandable between a delivery configuration and a deployed configuration. The annular elements are longitudinally aligned and connected at connection locations. Preferably, each connection location includes a foot extension, such as by an overlapping pattern between the longitudinally-adjacent annular elements or by a connector extending therebetween.

摘要翻译： 内置假体，例如支架，包括至少一个环形元件，所述至少一个环形元件由第一组支柱构件限定，所述第一组撑杆构件互相连接以限定靠近所述环形元件相对侧的顶点。 环形元件还包括在至少一对周向相邻的支柱构件之间延伸的脚延伸部。 脚部延伸部具有从周向相邻的支柱构件的对应端部周向延伸的第一和第二脚部，并且具有轮廓以提供至少两个弯曲区域。 第一和第二脚部在脚延伸部的脚趾部分处连接，并且在一对周向相邻的支柱构件之间限定圆周方向的顶点。 优选地，提供至少一个或多个另外的环形元件，每个环形元件由互连的支柱构件限定。 环形元件通常在输送配置和展开配置之间可扩展。 环形元件在连接位置处纵向对齐并连接。 优选地，每个连接位置包括脚部延伸部，例如通过在纵向相邻的环形元件之间的重叠图案，或者通过在它们之间延伸的连接器。

公开(公告)号：US08915954B2

公开(公告)日：2014-12-23

申请号：US13251929

申请日：2011-10-03

申请人： Eugene Young ,  Russ Borg ,  David Trask ,  Travis Richard Yribarren ,  Erik Eli

发明人： Eugene Young ,  Russ Borg ,  David Trask ,  Travis Richard Yribarren ,  Erik Eli

IPC分类号： A61F2/82 ,  A61F2/91 ,  A61F2/915

CPC分类号： A61F2/91 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2002/91591 ,  A61F2220/0041 ,  A61F2230/0054 ,  A61F2250/0098

摘要： Endoprosthesis for delivery in a body lumen is provided. The endoprosthesis includes an annular element defined by a set of interconnected strut members, each strut member including a first end and a second end. The first end of selected pairs of circumferentially-adjacent strut members of the annular element are interconnected to define apices proximate a first longitudinal side of the annular element and the second end of selected pairs circumferentially-adjacent strut members are interconnected to define apices proximate a second longitudinal side of the annular element. At least one of the selected pairs of circumferentially-adjacent strut members has a modulator disposed proximate the apex defined there between, the modulator having a first mode to allow expansion of the annular element from an unexpanded configuration toward an expanded configuration and a second mode to resist contraction of the annular element from the expanded configuration toward the unexpanded configuration.

摘要翻译： 提供用于在体腔内输送的内用假体。 内假体包括由一组相互连接的支柱构件限定的环形元件，每个支柱构件包括第一端和第二端。 环形元件的选定对的周向相邻的支柱构件的第一端互连以限定靠近环形元件的第一纵向侧面的顶点，并且所选择的对周向相邻的支柱构件的第二端互连以限定靠近第二 环形元件的纵向侧。 所选择的一对周向相邻的支柱构件中的至少一个具有设置在其间限定的顶点附近的调制器，调制器具有第一模式以允许环形元件从未膨胀构型朝向扩张构型膨胀，第二模式 防止环形元件从膨胀构型向未膨胀构型的收缩。

公开(公告)号：US07794489B2

公开(公告)日：2010-09-14

申请号：US11479644

申请日：2006-06-30

申请人： Daniel H. Shumer ,  Amelia Lasser ,  Jimmy Jen ,  Jill Nicole Malin ,  Howard H. Huang ,  Erik Eli ,  Claus Volkl ,  Juergen Anton Haun

发明人： Daniel H. Shumer ,  Amelia Lasser ,  Jimmy Jen ,  Jill Nicole Malin ,  Howard H. Huang ,  Erik Eli ,  Claus Volkl ,  Juergen Anton Haun

IPC分类号： A61F2/84

CPC分类号： A61F2/95 ,  A61F2/966 ,  A61F2002/9517

摘要： The invention is directed to a delivery system for delivering a medical device. The delivery system includes an inner member having a proximal end and a distal end. The inner member defines a longitudinal axis between the proximal end and the distal end. A tip is formed at the distal end of the inner member. A bumper is freely disposed on the inner member. The bumper has a proximal end and a distal end. A seat is defined between the tip and the distal end of the bumper. Additionally, a sheath is disposed about the inner member, the sheath having a proximal end and a distal end. The sheath is movable from a first sheath position substantially covering the seat, and a second sheath position axially offset to expose the seat. The invention also includes a handle in contact with the proximal end of the inner member.

公开(公告)号：US20070021834A1

公开(公告)日：2007-01-25

申请号：US11479643

申请日：2006-06-30

申请人： Eugene Young ,  Russ Borg ,  David Trask ,  Travis Yribarren ,  Erik Eli

发明人： Eugene Young ,  Russ Borg ,  David Trask ,  Travis Yribarren ,  Erik Eli

IPC分类号： A61F2/28

CPC分类号： A61F2/91 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2002/91591 ,  A61F2220/0041 ,  A61F2230/0054 ,  A61F2250/0098

摘要： Endoprosthesis, such as a stent, includes at least one annular element defined by a first set of strut members interconnected to define apices proximate opposite sides of the annular element. The annular element further includes a foot extension extending between at least one pair of circumferentially-adjacent strut members. The foot extension has first and second foot portions extending circumferentially from corresponding ends of the circumferentially-adjacent strut members, and are contoured to provide at least two areas of flexure. The first and second foot portions are joined at a toe portion of the foot extension, and define a circumferentially-directed apex between the pair of circumferentially-adjacent strut members. Preferably, at least one or more additional annular elements, each defined by interconnected strut members, are provided. The annular elements are generally expandable between a delivery configuration and a deployed configuration. The annular elements are longitudinally aligned and connected at connection locations with connectors, wherein at least one of the connectors is constructed of a bio-absorbable material.

摘要翻译： 内置假体，例如支架，包括至少一个环形元件，所述至少一个环形元件由第一组支柱构件限定，所述第一组撑杆构件互相连接以限定靠近所述环形元件相对侧的顶点。 环形元件还包括在至少一对周向相邻的支柱构件之间延伸的脚延伸部。 脚部延伸部具有从周向相邻的支柱构件的对应端部周向延伸的第一和第二脚部，并且具有轮廓以提供至少两个弯曲区域。 第一和第二脚部在脚延伸部的脚趾部分处连接，并且在一对周向相邻的支柱构件之间限定圆周方向的顶点。 优选地，提供至少一个或多个另外的环形元件，每个环形元件由互连的支柱构件限定。 环形元件通常在输送配置和展开配置之间可扩展。 环形元件在与连接器的连接位置处纵向对准并连接，其中至少一个连接器由生物吸收材料构成。

公开(公告)号：US20070021827A1

公开(公告)日：2007-01-25

申请号：US11535529

申请日：2006-09-27

申请人： David Lowe ,  Erik Eli ,  Jeff Pappas ,  Howard Huang ,  Anton Clifford ,  Kevin Kang

发明人： David Lowe ,  Erik Eli ,  Jeff Pappas ,  Howard Huang ,  Anton Clifford ,  Kevin Kang

IPC分类号： A61F2/90

CPC分类号： A61F2/91 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2210/0076 ,  A61F2230/0043 ,  A61F2230/0054

摘要： Endoprosthesis, such as a stent, includes at least one annular element defined by a first set of strut members interconnected to define apices proximate opposite sides of the annular element. The annular element further includes a foot extension extending between at least one pair of circumferentially-adjacent strut members. The foot extension has first and second foot portions extending circumferentially from corresponding ends of the circumferentially-adjacent strut members, and are contoured to provide at least two areas of flexure. The first and second foot portions are joined at a toe portion of the foot extension, and define a circumferentially-directed apex between the pair of circumferentially-adjacent strut members. Preferably, at least one or more additional annular elements, each defined by interconnected strut members, are provided. The annular elements are generally expandable between a delivery configuration and a deployed configuration. The annular elements are longitudinally aligned and connected at connection locations. Preferably, each connection location includes a foot extension, such as by an overlapping pattern between the longitudinally-adjacent annular elements or by a connector extending therebetween.

摘要翻译： 内置假体，例如支架，包括至少一个环形元件，所述至少一个环形元件由第一组支柱构件限定，所述第一组撑杆构件互相连接以限定靠近所述环形元件相对侧的顶点。 环形元件还包括在至少一对周向相邻的支柱构件之间延伸的脚延伸部。 脚部延伸部具有从周向相邻的支柱构件的对应端部周向延伸的第一和第二脚部，并且具有轮廓以提供至少两个挠曲区域。 第一和第二脚部在脚延伸部的脚趾部分处连接，并且在一对周向相邻的支柱构件之间限定圆周方向的顶点。 优选地，提供至少一个或多个另外的环形元件，每个环形元件由互连的支柱构件限定。 环形元件通常在输送配置和展开配置之间可扩展。 环形元件在连接位置处纵向对齐并连接。 优选地，每个连接位置包括脚部延伸部，例如通过在纵向相邻的环形元件之间的重叠图案，或者通过在它们之间延伸的连接器。

公开(公告)号：US20070100422A1

公开(公告)日：2007-05-03

申请号：US11479644

申请日：2006-06-30

申请人： Daniel Shumer ,  Amelia Lasser ,  Jimmy Jen ,  Jill Malin ,  Howard Huang ,  Erik Eli ,  Claus Volkl ,  Juergen Hahn

发明人： Daniel Shumer ,  Amelia Lasser ,  Jimmy Jen ,  Jill Malin ,  Howard Huang ,  Erik Eli ,  Claus Volkl ,  Juergen Hahn

IPC分类号： A61F2/06

CPC分类号： A61F2/95 ,  A61F2/966 ,  A61F2002/9517

摘要： The invention is directed to a delivery system for delivering a medical device. The delivery system includes an inner member having a proximal end and a distal end. The inner member defines a longitudinal axis between the proximal end and the distal end. A tip is formed at the distal end of the inner member. A bumper is freely disposed on the inner member. The bumper has a proximal end and a distal end. A seat is defined between the tip and the distal end of the bumper. Additionally, a sheath is disposed about the inner member, the sheath having a proximal end and a distal end. The sheath is movable from a first sheath position substantially covering the seat, and a second sheath position axially offset to expose the seat. The invention also includes a handle in contact with the proximal end of the inner member.

摘要翻译： 本发明涉及用于递送医疗装置的递送系统。 输送系统包括具有近端和远端的内部构件。 内部构件限定近端和远端之间的纵向轴线。 尖端形成在内部构件的远端。 保险杠自由地设置在内部构件上。 保险杠具有近端和远端。 在保险杠的尖端和远端之间限定座椅。 此外，护套围绕内部构件设置，护套具有近端和远端。 护套可从基本上覆盖座椅的第一护套位置移动，并且第二护套位置轴向偏置以露出座椅。 本发明还包括与内部构件的近端接触的手柄。

公开(公告)号：US07128756B2

公开(公告)日：2006-10-31

申请号：US10430644

申请日：2003-05-06

申请人： David Lowe ,  Erik Eli ,  Jeff Pappas ,  Howard H. Huang ,  Anton G. Clifford ,  Kevin Kang

发明人： David Lowe ,  Erik Eli ,  Jeff Pappas ,  Howard H. Huang ,  Anton G. Clifford ,  Kevin Kang

IPC分类号： A61F2/06

CPC分类号： A61F2/91 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2210/0076 ,  A61F2230/0043 ,  A61F2230/0054

摘要： Endoprosthesis, such as a stent, includes at least one annular element defined by a first set of strut members interconnected to define apices proximate opposite sides of the annular element. The annular element further includes a foot extension extending between at least one pair of circumferentially-adjacent strut members. The foot extension has first and second foot portions extending circumferentially from corresponding ends of the circumferentially-adjacent strut members, and are contoured to provide at least two areas of flexure. The first and second foot portions are joined at a toe portion of the foot extension, and define a circumferentially-directed apex between the pair of circumferentially-adjacent strut members. Preferably, at least one or more additional annular elements, each defined by interconnected strut members, are provided. The annular elements are generally expandable between a delivery configuration and a deployed configuration. The annular elements are longitudinally aligned and connected at connection locations. Preferably, each connection location includes a foot extension, such as by an overlapping pattern between the longitudinally-adjacent annular elements or by a connector extending therebetween.