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18 条记录 (耗时 0.034 秒)

    9A,11-2C-bicyclic 9a-azalide derivatives
    1.
    发明申请
    9A,11-2C-bicyclic 9a-azalide derivatives 有权
    9A，11-2C-双环9a-氮杂环戊二烯衍生物

    公开(公告)号：US20060154881A1

    公开(公告)日：2006-07-13

    申请号：US11324502

    申请日：2006-01-03

    申请人： Yat Or ,  Ly Phan ,  Guoqiang Wang ,  Yanchun Wang ,  Yulin Peng

    发明人： Yat Or ,  Ly Phan ,  Guoqiang Wang ,  Yanchun Wang ,  Yulin Peng

    IPC分类号： A61K31/7052 ,  C07H17/08

    CPC分类号： C07H17/08

    摘要： The present invention discloses compounds of formulae I and II, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

    摘要翻译： 本发明公开了式I和II的化合物或其药学上可接受的盐，酯或前药：其表现出抗菌性质。 本发明还涉及包含上述化合物的药物组合物，用于给予需要抗生素治疗的受试者。 本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。 本发明还包括制备本发明化合物的方法。

    9a,11-3C-bicyclic 9a-azalide derivatives
    3.
    发明申请
    9a,11-3C-bicyclic 9a-azalide derivatives 有权
    9a，11-3C-双环9a-氮杂衍生物

    公开(公告)号：US20050090460A1

    公开(公告)日：2005-04-28

    申请号：US10946339

    申请日：2004-09-21

    申请人： Guoqiang Wang ,  Yulin Peng ,  Yanchun Wang ,  Ly Phan ,  Yat Or

    发明人： Guoqiang Wang ,  Yulin Peng ,  Yanchun Wang ,  Ly Phan ,  Yat Or

    IPC分类号： A61K31/7052 ,  C07H17/08

    CPC分类号： C07H17/08

    摘要： The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

    摘要翻译： 本发明公开了式I化合物或其药学上可接受的盐，酯或前药：其表现出抗菌性质。 本发明还涉及包含上述化合物的药物组合物，用于给予需要抗生素治疗的受试者。 本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。 本发明还包括制备本发明化合物的方法。

    6-11 Bridged oxime erythromycin derivatives
    5.
    发明申请
    6-11 Bridged oxime erythromycin derivatives 审中-公开
    6-11桥接肟红霉素衍生物

    公开(公告)号：US20060252710A1

    公开(公告)日：2006-11-09

    申请号：US11122251

    申请日：2005-05-04

    申请人： Guoqiang Wang ,  Ly Phan ,  Yat Or ,  Yao-Ling Qiu ,  Deqiang Niu ,  Yulin Peng ,  Marina Busuyek ,  Yanchun Wang ,  Suanne Nakajima

    发明人： Guoqiang Wang ,  Ly Phan ,  Yat Or ,  Yao-Ling Qiu ,  Deqiang Niu ,  Yulin Peng ,  Marina Busuyek ,  Yanchun Wang ,  Suanne Nakajima

    IPC分类号： C07H17/08 ,  A61K31/7052

    CPC分类号： C07H17/08

    摘要： The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes processes by which to make the compounds of the present invention.

    摘要翻译： 本发明公开了式I化合物或其药学上可接受的盐，酯或前药：其表现出抗菌性质。 本发明还涉及包含上述化合物的药物组合物，用于给予需要抗生素治疗的受试者。 本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。 本发明还包括制备本发明化合物的方法。

    6-11 Bicyclic ketolide derivatives
    7.
    发明申请
    6-11 Bicyclic ketolide derivatives 有权
    6-11双环酮内酯衍生物

    公开(公告)号：US20050282758A1

    公开(公告)日：2005-12-22

    申请号：US11154260

    申请日：2005-06-16

    申请人： Deqiang Niu ,  Guoqiang Wang ,  Yat Or ,  Ly Phan

    发明人： Deqiang Niu ,  Guoqiang Wang ,  Yat Or ,  Ly Phan

    IPC分类号： A61K31/7052 ,  A61K45/06 ,  C07H17/08

    CPC分类号： C07H17/08 ,  A61K31/7052 ,  A61K45/06 ,  Y02A50/401 ,  Y02A50/478 ,  A61K2300/00

    摘要： The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

    摘要翻译： 本发明公开了式I化合物或其药学上可接受的盐，酯或前药：其表现出抗菌性质。 本发明还涉及包含上述化合物的药物组合物，用于给予需要抗生素治疗的受试者。 本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。 本发明还包括制备本发明化合物的方法。

    6-11 Bicyclic erythromycin derivatives
    8.
    发明申请
    6-11 Bicyclic erythromycin derivatives 失效
    6-11双环红霉素衍生物

    公开(公告)号：US20050187169A1

    公开(公告)日：2005-08-25

    申请号：US11029640

    申请日：2005-01-05

    申请人： Nha Vo ,  Guoqiang Wang ,  Guoyou Xu ,  Ying Hou ,  Ying Sun ,  Ly Phan ,  Zhe Wang ,  Yat Or

    发明人： Nha Vo ,  Guoqiang Wang ,  Guoyou Xu ,  Ying Hou ,  Ying Sun ,  Ly Phan ,  Zhe Wang ,  Yat Or

    IPC分类号： A61K31/70 ,  A61K31/7048 ,  C07H17/08

    CPC分类号： C07H17/08

    摘要： The present invention discloses compounds of formulaes I, II, III, or IV, or a racemate, enantiomer, regioisomer, salt, ester or prodrug thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

    摘要翻译： 本发明公开了式I，II，III或IV的化合物或其外消旋体，对映异构体，区域异构体，盐，酯或前药：其表现出抗菌性质。 本发明还涉及包含上述化合物的药物组合物，用于给予需要抗生素治疗的受试者。 本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。 本发明还包括制备本发明化合物的方法。

    Novel bicyclic 9a-azalide derivatives
    9.
    发明申请
    Novel bicyclic 9a-azalide derivatives 失效
    新型双环9a-氮杂衍生物

    公开(公告)号：US20060069048A1

    公开(公告)日：2006-03-30

    申请号：US11236043

    申请日：2005-09-27

    申请人： Yat Or ,  Yao-Ling Qiu ,  Guoqiang Wang ,  Deqiang Niu ,  Ly Phan

    发明人： Yat Or ,  Yao-Ling Qiu ,  Guoqiang Wang ,  Deqiang Niu ,  Ly Phan

    IPC分类号： C07H17/08 ,  A61K31/7052

    CPC分类号： C07H17/08

    摘要： The present invention discloses compounds of formulae I and II, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

    摘要翻译： 本发明公开了式I和II的化合物或其药学上可接受的盐，酯或前药：