公开(公告)号：US20180073023A1

公开(公告)日：2018-03-15

申请号：US15690699

申请日：2017-08-30

Applicant: HITACHI, LTD.

Inventor： Hiroko MATSUNAGA ,  Maiko TANABE

IPC: C12N15/113 ,  A61K31/70 ,  C12Q1/68

CPC classification number: C12N15/113 ,  A61K31/70 ,  A61K38/00 ,  C12N15/1034 ,  C12N15/1065 ,  C12N2310/152 ,  C12N2310/53 ,  C12Q1/6806 ,  C12Q1/6813 ,  C12Q2521/501 ,  C12Q2525/161 ,  C12Q2525/191 ,  C12Q2531/113 ,  C12Q2531/125 ,  C12Q2535/122 ,  C12Q2563/179 ,  C12Q2565/514

Abstract: An object of the present invention is to provide a circular single-stranded nucleic acid, and a method for preparing the same and a method for using the same. A circular single-stranded nucleic acid according to one embodiment of the present invention is a circular single-stranded nucleic acid for determining a target base on a genomic DNA, and includes a first single-stranded nucleic acid which has the target base or a complementary base thereto and is a part of one of the strands of the genomic DNA, and a second single-stranded nucleic acid which has an index sequence to serve as an index of a cell, from which the genomic DNA is derived, or a complementary sequence thereto.