公开(公告)号：US20180326224A1

公开(公告)日：2018-11-15

申请号：US15775197

申请日：2015-11-13

Applicant: HITACHI, LTD.

Inventor： Masumi UMEZAWA ,  Shinichiro FUJITAKA ,  Taisuke TAKAYANAGI

IPC: A61N5/10

CPC classification number: A61N5/1043 ,  A61N5/1071 ,  A61N2005/1072 ,  A61N2005/1074 ,  A61N2005/1087 ,  G21K1/025

Abstract: The invention provides a particle therapy system in which whether to perform any one irradiation method of a raster scanning method and a discrete spot scanning method can also be selected based on previous selection depending on a target volume 41 of a patient 4 to be irradiated, and either of the irradiation methods of the raster scanning method and the discrete spot scanning method is configured to be capable of being performed by one irradiation apparatus 500. Therefore, a small particle therapy system capable of achieving both higher accuracy irradiation and high dose rate improvement is provided.

公开(公告)号：US20160150630A1

公开(公告)日：2016-05-26

申请号：US14926501

申请日：2015-10-29

Applicant: Hitachi, Ltd.

Inventor： Kazunori TSUBUKU ,  Masumi UMEZAWA ,  Takashi IGA ,  Kouji TOBINAGA

IPC: H05H7/00 ,  A61N5/01 ,  H01J37/317 ,  H05H13/04 ,  H05H9/00

CPC classification number: H05H7/001 ,  A61N5/01 ,  A61N5/1068 ,  A61N2005/1087 ,  H01J37/1475 ,  H01J37/3005 ,  H01J37/3178 ,  H05H7/08 ,  H05H13/04

Abstract: Provided are a charged particle beam generation apparatus, a charged particle beam irradiation apparatus, a particle beam therapy system, and a charged particle beam generation apparatus operating method capable of implementing injection of a charged particle beam into a circular accelerator at an arbitrary timing by setting a normal operation period of a linear accelerator to be larger than a shortest period and securing a stability of the beam. In timing control of controlling injecting, accelerating, emitting, and decelerating processes of a synchrotron 200, after an end of the emitting process, a linear accelerator 111 is allowed to stop repetition of an operation based on an after-end-of-emitting-process timing signal to be in a stand-by state and is allowed to be start the repetition of the operation in a constant period based on a master signal.

Abstract translation: 提供了一种带电粒子束产生装置，带电粒子束照射装置，粒子束治疗系统和带电粒子束产生装置的操作方法，其能够通过设定在任意时刻将带电粒子束注入圆形加速器 直线加速器的正常操作周期大于最短周期并确保光束的稳定性。 在同步加速器200的控制喷射，加速，发射和减速处理的定时控制中，在发光处理结束之后，允许线性加速器111停止重复基于发射后的发射 - 处理定时信号处于待机状态，并且允许基于主信号在恒定周期中开始重复操作。

公开(公告)号：US20130267756A1

公开(公告)日：2013-10-10

申请号：US13857573

申请日：2013-04-05

Applicant: HITACHI, LTD.

Inventor： Satoshi TOTAKE ,  Masumi UMEZAWA ,  Tomohisa IMAGAWA

IPC: A61N5/10

CPC classification number: A61N5/1043 ,  A61N5/103 ,  A61N5/1048 ,  A61N5/1049 ,  A61N5/1077 ,  A61N2005/1087

Abstract: A particle therapy system is capable of reducing an increase in treatment time caused by the initialization operation of magnets in the execution of the scanning irradiation method successively changing the energy level of a beam extracted from an accelerator. An irradiation control apparatus has a scheme that calculates setting vales of excitation current for bending magnets for a transport system on every irradiation condition (energy condition), and sets appropriate excitation current values according to the irradiation sequence. The irradiation control apparatus 35 prestores in a current supply control table 1 reference current values determined corresponding to energy levels of the ion beam, prestores in current supply compensation value tables 1, 2 compensation current values determined corresponding to energy levels of the ion beam and numbers of times of changing the energy level, and calculates the excitation current value of the magnets by using the values prestored in the tables.

公开(公告)号：US20170303384A1

公开(公告)日：2017-10-19

申请号：US15513584

申请日：2014-12-08

Applicant: Hitachi, Ltd.

Inventor： Takamichi AOKI ,  Futaro EBINA ,  Hideaki NISHIUCHI ,  Shigemitsu HARA ,  Masumi UMEZAWA ,  Takayoshi SEKI

IPC: H05H13/00 ,  H05H13/04 ,  A61N5/10

CPC classification number: H05H13/005 ,  A61N5/1077 ,  A61N2005/1087 ,  H05H7/08 ,  H05H13/04 ,  H05H2277/11

Abstract: The accelerator includes a circular vacuum container which contains a circular return yoke. With respect to the central axis of the vacuum container, an incidence electrode is arranged towards the entrance of a beam emission path inside of the return yoke. Inside of the return yoke, electrodes are arranged radially from the incidence electrode in the periphery of the incidence electrode. Recesses are arranged alternately with the electrodes in the circumferential direction of the return yoke. In the vacuum container, an orbit-concentric region is formed in which multiple beam orbits centered on the incidence electrode are present, and, in the periphery of said region, an orbit-eccentric area is formed in which multiple beam orbits eccentric to the incidence electrode are present. In the orbit-eccentric region, the beam orbits between the incidence electrode and the entrance to the beam emission path are denser.

公开(公告)号：US20150217138A1

公开(公告)日：2015-08-06

申请号：US14686227

申请日：2015-04-14

Applicant: HITACHI, LTD.

Inventor： Rintaro FUJIMOTO ,  Yoshihiko NAGAMINE ,  Masumi UMEZAWA ,  Toru UMEKAWA ,  Yusuke FUJII ,  Hiroshi AKIYAMA

IPC: A61N5/10

CPC classification number: A61N5/1065 ,  A61N5/103 ,  A61N5/1043 ,  A61N2005/1087

Abstract: In a particle therapy treatment planning system for creating treatment plan data, the movement of a target (patient's affected area) is extracted from plural tomography images of the target, and the direction of scanning is determined by projecting the extracted movement on a scanning plane scanned by scanning magnets. Irradiation positions are arranged on straight lines parallel with the scanning direction making it possible to calculate a scanning path for causing scanning to be made mainly along the direction of movement of the target. The treatment planning system can thereby realize dose distribution with improved uniformity.

Abstract translation: 在用于创建治疗计划数据的粒子治疗计划系统中，从目标的多个断层摄影图像中提取目标（患者受影响区域）的运动，并且通过在扫描的扫描平面上投影所提取的运动来确定扫描的方向 通过扫描磁铁。 照射位置配置在与扫描方向平行的直线上，从而可以计算用于使扫描主要沿目标的移动方向进行扫描的扫描路径。 因此，治疗计划系统可以实现均匀性的改善。

公开(公告)号：US20170339778A1

公开(公告)日：2017-11-23

申请号：US15533530

申请日：2014-12-08

Applicant: Hitachi, Ltd.

Inventor： Takamichi AOKI ,  Fuutarou EBINA ,  Masumi UMEZAWA ,  Shigemitsu HARA ,  Hideaki NISHIUCHI ,  Takayoshi SEKI

IPC: H05H7/04 ,  A61N5/10 ,  H05H13/04 ,  H05H7/10

CPC classification number: H05H7/04 ,  A61N5/10 ,  A61N5/1077 ,  A61N2005/1087 ,  H05H7/10 ,  H05H13/04 ,  H05H13/10 ,  H05H2007/045 ,  H05H2007/048 ,  H05H2277/11

Abstract: Ion beams are efficiently extracted with an accelerator that includes a circular vacuum container including a pair of circular return yokes facing each other. Six magnetic poles are radially disposed from the injection electrode at the periphery thereof in the return yoke. Six recessions are disposed alternately with the respective magnetic poles in the circumferential direction of the return yoke. In the vacuum container, a concentric trajectory region, in which multiple beam turning trajectories centered around the injection electrode are present, is formed, and an eccentric trajectory region, in which multiple beam turning trajectories eccentric from the injection electrode are present, is formed around the region. In the eccentric trajectory region, the beam turning trajectories are dense between the injection electrode and the inlet of the beam extraction path. Gaps between the beam turning trajectories are wide in a direction 180° opposite to the inlet of the beam extraction path.

公开(公告)号：US20170318657A1

公开(公告)日：2017-11-02

申请号：US15531806

申请日：2014-12-08

Applicant: Hitachi, Ltd.

Inventor： Takamichi AOKI ,  Fuutarou EBINA ,  Hideaki NISHIUCHI ,  Shigemitsu HARA ,  Masumi UMEZAWA ,  Takayoshi SEKI

IPC: H05H7/00 ,  H05H7/02 ,  H05H7/04 ,  H05H7/08 ,  H05H13/00 ,  A61N5/10

CPC classification number: H05H7/001 ,  A61N5/10 ,  A61N5/1077 ,  A61N2005/1087 ,  H05H7/02 ,  H05H7/04 ,  H05H7/08 ,  H05H13/005 ,  H05H13/04 ,  H05H2007/002 ,  H05H2007/004 ,  H05H2007/008 ,  H05H2007/025 ,  H05H2007/045 ,  H05H2007/048 ,  H05H2007/082 ,  H05H2007/087

Abstract: An accelerator 4 includes a circular vacuum container including circular return yokes 5A, 5B. An injection electrode 18 is disposed closer to an inlet of a beam extraction path 20 in the return yoke 5B than a central axis C of the vacuum container. Magnetic poles 7A to 7F are radially disposed from the injection electrode 18 at the periphery of the injection electrode 18 in the return yoke 5B. Recessions 29A to 29F are disposed alternately with the magnetic poles 7A to 7F in the circumferential direction of the return yoke 5B. In the vacuum container, a concentric trajectory region, in which multiple beam turning trajectories centered around the injection electrode 18 are present, is formed, and an eccentric trajectory region, in which multiple beam turning trajectories eccentric from the injection electrode 18 are present, is formed around the region.

公开(公告)号：US20150290475A1

公开(公告)日：2015-10-15

申请号：US14726824

申请日：2015-06-01

Applicant: HITACHI, LTD. ,  NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY

Inventor： Yusuke FUJII ,  Toru UMEKAWA ,  Masumi UMEZAWA ,  Hiroki SHIRATO ,  Kikuo UMEGAKI ,  Naoki MIYAMOTO ,  Taeko MATSUURA

IPC: A61N5/10

CPC classification number: A61N5/1068 ,  A61N5/1077 ,  A61N2005/1074 ,  A61N2005/1087

Abstract: A charged particle irradiation system is capable of shortening the irradiation time and the treatment time by performing efficient irradiation even when irregular variation occurs in the irradiation object during the gating irradiation. The extraction of the beam is stopped upon reception of a regular extraction permission end signal which is outputted based on a regular movement signal. An extractable state maintaining function operates upon the reception of the extraction permission end signal. When a preset standby time elapses without receiving an extraction permission start signal again during the standby time, the extractable state maintaining function finishes its operation and a charged particle beam generator decelerates the beam. Also, the extraction of the beam is stopped due to reception of an irregular extraction permission end signal during the irradiation. When the extraction permission start signal is received again during the standby time, the extraction of the beam is restarted.

Abstract translation: 带电粒子照射系统即使在门控照射期间在照射物体中发生不规则变化，也能够通过高效照射缩短照射时间和处理时间。 在接收到基于规则移动信号输出的常规提取许可结束信号时，停止提取光束。 可提取状态维持功能在接收到提取许可结束信号时进行操作。 当在待机时间期间经过预设待机时间而不再接收到提取许可开始信号时，可提取状态维持功能完成其操作，并且带电粒子束发生器使光束减速。 此外，由于在照射期间接收到不规则的提取许可结束信号，停止提取光束。 当在待机时间期间再次接收到提取许可开始信号时，重新开始提取光束。

公开(公告)号：US20150115179A1

公开(公告)日：2015-04-30

申请号：US14524495

申请日：2014-10-27

Applicant: HITACHI, LTD. ,  NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY

Inventor： Kazuo HIRAMOTO ,  Masumi UMEZAWA ,  Shinichiro FUJITAKA ,  Hiroki SHIRATO ,  Shinichi SHIMIZU ,  Kikuo UMEGAKI

IPC: A61N5/10 ,  G21K1/08 ,  G21K5/04

CPC classification number: A61N5/1048 ,  A61N5/1043 ,  A61N5/1081 ,  A61N2005/1074 ,  A61N2005/1087 ,  G21K1/08 ,  G21K5/04

Abstract: First ions and second ions that are heavier than first ions are generated in an ion source. One kind of ions of the first ions and second ions is injected into an accelerator by action of a switching magnet and accelerated in the accelerator. An ion beam including the one kind of ions is extracted from the accelerator to a beam transport system and a tumor volume of a patient is irradiated with the ion beam from an irradiation nozzle. In the irradiation of the ion beam, a tumor volume depth and the largest underwater range of each ion species are compared, and an ion species in which the tumor volume depth becomes the longest underwater range or lower is injected into the accelerator, and accelerated by the accelerator. The tumor volume is irradiated with the ion species.

Abstract translation: 在离子源中产生比第一离子重的第一离子和第二离子。 第一离子和第二离子的一种离子通过切换磁体的作用被注入加速器，并在加速器中加速。 将包括一种离子的离子束从加速器提取到束输送系统，并且用来自照射喷嘴的离子束照射患者的肿瘤体积。 在照射离子束时，比较每个离子种类的肿瘤体积深度和最大的水下范围，将其中肿瘤体积深度变为最长的水中范围或更低的离子种类注入加速器，并加速 加速器。 用离子种类照射肿瘤体积。

公开(公告)号：US20220355129A1

公开(公告)日：2022-11-10

申请号：US17760548

申请日：2020-06-24

Applicant: HITACHI, LTD.

Inventor： Yusuke FUJII ,  Manabu AOKI ,  Masumi UMEZAWA

IPC: A61N5/10 ,  A61B5/055

Abstract: The system includes a bed on which an irradiation target is mounted, an irradiation device that irradiates the irradiation target with a particle beam, and a magnetic resonance imaging apparatus that captures an image of an irradiation object and includes a magnet that generates a static magnetic field in an image capturing space in which the irradiation target is disposed, and a yoke disposed outside the image capturing space and through which a magnetic flux of the generated magnetic field passes. The irradiation device 21 is disposed on a back surface side of the yoke when viewed from the image capturing space, and irradiates the irradiation target with the particle beam from a through-hole or gap provided in the yoke. A direction in which the particle beam enters the image capturing space intersects with a direction of a static magnetic field applied to the image capturing space by the magnet.