公开(公告)号：US20180326224A1

公开(公告)日：2018-11-15

申请号：US15775197

申请日：2015-11-13

Applicant: HITACHI, LTD.

Inventor： Masumi UMEZAWA ,  Shinichiro FUJITAKA ,  Taisuke TAKAYANAGI

IPC: A61N5/10

CPC classification number: A61N5/1043 ,  A61N5/1071 ,  A61N2005/1072 ,  A61N2005/1074 ,  A61N2005/1087 ,  G21K1/025

Abstract: The invention provides a particle therapy system in which whether to perform any one irradiation method of a raster scanning method and a discrete spot scanning method can also be selected based on previous selection depending on a target volume 41 of a patient 4 to be irradiated, and either of the irradiation methods of the raster scanning method and the discrete spot scanning method is configured to be capable of being performed by one irradiation apparatus 500. Therefore, a small particle therapy system capable of achieving both higher accuracy irradiation and high dose rate improvement is provided.

公开(公告)号：US20170243665A1

公开(公告)日：2017-08-24

申请号：US15437826

申请日：2017-02-21

Applicant: Hitachi, Ltd. ,  NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY

Inventor： Taisuke TAKAYANAGI ,  Shinichiro FUJITAKA ,  Chihiro NAKASHIMA ,  Tomoki MURATA ,  Taeko MATSUURA ,  Naoki MIYAMOTO ,  Kikuo UMEGAKI ,  Yuichi HIRATA

IPC: G21K1/10 ,  G21K5/04 ,  H05H13/04

CPC classification number: G21K1/10 ,  A61N5/1077 ,  A61N2005/1087 ,  A61N2005/1095 ,  G21K5/04 ,  H05H7/12 ,  H05H13/04 ,  H05H2007/004

Abstract: A structure configuring a ridge filter has line symmetry about a line vertical to a depth direction passing the center of the structure. A small structure obtained in such a way that the structure is divided by this line has a bilaterally asymmetric shape about a center line in an iterative direction, and has a point symmetric shape about an intersection between the center line in the iterative direction and the center line in the depth direction. Thicknesses in the iterative direction of an uppermost stream surface and a lowermost stream surface in the depth direction are equal to each other. The structure is configured so that a thick portion in the iterative direction of the uppermost stream surface and the lowermost stream surface is not present in the depth direction.

公开(公告)号：US20180200534A1

公开(公告)日：2018-07-19

申请号：US15821889

申请日：2017-11-24

Applicant: Hitachi, Ltd.

Inventor： Takahiro YAMADA ,  Taisuke TAKAYANAGI ,  Rintarou FUJIMOTO ,  Shinichiro FUJITAKA ,  Takuya NOMURA

IPC: A61N5/10

CPC classification number: A61N5/103 ,  A61N5/1043 ,  A61N5/1067 ,  A61N5/1071 ,  A61N5/1077 ,  A61N2005/1074 ,  A61N2005/1087

Abstract: There is provided a treatment planning system and a particle therapy system. In the related art, it is unable to determine optimum beam intensity in irradiation for which discrete spot irradiation and continuous beam irradiation coexist. There is provided a treatment planning system that includes a spot determination unit that divides an irradiation region to be irradiated with a charged particle beam into a plurality of layers in an advancing direction of the charged particle beam and disposes a plurality of irradiation spots, which becomes irradiation points of the charged particle beam, in the layers and a beam intensity determination unit that determines beam intensity for each of the layers by evaluating the irradiation time by changing the beam intensity in a range of a condition of change in dose distribution which is set in advance.

公开(公告)号：US20170304651A1

公开(公告)日：2017-10-26

申请号：US15513276

申请日：2015-05-12

Applicant: HITACHI, LTD.

Inventor： Taisuke TAKAYANAGI ,  Shusuke HIRAYAMA ,  Shinichiro FUJITAKA

IPC: A61N5/10

CPC classification number: A61N5/1031 ,  A61N5/10 ,  A61N5/1043 ,  A61N2005/1034 ,  A61N2005/1087

Abstract: A radiation therapy planning apparatus performs dose calculation at high speed and with high accuracy for radiation therapy in a scanning irradiation method. The apparatus includes a display, an arithmetic processing apparatus, a memory, and a data server, which is connected to a particle beam irradiation apparatus. A dose calculation unit of the arithmetic processing apparatus calculates dose distribution by a simplified Monte Carlo algorithm, and corrects the dose distribution by a decreasing rate stored in a particle number decreasing rate table of the memory, and stores the corrected dose distribution in an integrated dose distribution table. By using the simplified Monte Carlo algorithm and the particle number decreasing rate that corrects the simplified Monte Carlo algorithm, the dose distribution is calculated, and thereby, it is possible to realize a radiation therapy planning apparatus that performs dose calculation at a high speed with high accuracy.

公开(公告)号：US20150115179A1

公开(公告)日：2015-04-30

申请号：US14524495

申请日：2014-10-27

Applicant: HITACHI, LTD. ,  NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY

Inventor： Kazuo HIRAMOTO ,  Masumi UMEZAWA ,  Shinichiro FUJITAKA ,  Hiroki SHIRATO ,  Shinichi SHIMIZU ,  Kikuo UMEGAKI

IPC: A61N5/10 ,  G21K1/08 ,  G21K5/04

CPC classification number: A61N5/1048 ,  A61N5/1043 ,  A61N5/1081 ,  A61N2005/1074 ,  A61N2005/1087 ,  G21K1/08 ,  G21K5/04

Abstract: First ions and second ions that are heavier than first ions are generated in an ion source. One kind of ions of the first ions and second ions is injected into an accelerator by action of a switching magnet and accelerated in the accelerator. An ion beam including the one kind of ions is extracted from the accelerator to a beam transport system and a tumor volume of a patient is irradiated with the ion beam from an irradiation nozzle. In the irradiation of the ion beam, a tumor volume depth and the largest underwater range of each ion species are compared, and an ion species in which the tumor volume depth becomes the longest underwater range or lower is injected into the accelerator, and accelerated by the accelerator. The tumor volume is irradiated with the ion species.

Abstract translation: 在离子源中产生比第一离子重的第一离子和第二离子。 第一离子和第二离子的一种离子通过切换磁体的作用被注入加速器，并在加速器中加速。 将包括一种离子的离子束从加速器提取到束输送系统，并且用来自照射喷嘴的离子束照射患者的肿瘤体积。 在照射离子束时，比较每个离子种类的肿瘤体积深度和最大的水下范围，将其中肿瘤体积深度变为最长的水中范围或更低的离子种类注入加速器，并加速 加速器。 用离子种类照射肿瘤体积。

公开(公告)号：US20150099918A1

公开(公告)日：2015-04-09

申请号：US14497891

申请日：2014-09-26

Applicant: HITACHI, LTD.

Inventor： Taisuke TAKAYANAGI ,  Shinichiro FUJITAKA ,  Chihiro NAKASHIMA ,  Koji MATSUDA

IPC: A61N5/10 ,  G01T1/02

CPC classification number: A61N5/1071 ,  G01T1/02 ,  G01T1/29

Abstract: A radiation measuring device having a plurality of sensors configured to generate charges in response to the radiation includes a signal processing device. The signal processing device uses an signal generated by a proton beam irradiation device upon changing of beam energy and causes accumulation values of charges output from the sensors to be separately stored in a main control device for each value of the energy. The main control device calculates depth dose profiles for values of the beam energy from the accumulation values stored in the main control device and representing the charges. The main control device calculates a range of the beam for each of the values of the beam energy from the depth dose profiles, corrects the depth dose profiles for the values of the beam energy using a correction coefficient that depends on the range and sums the corrected depth dose profiles.

Abstract translation: 具有被配置为响应于辐射产生电荷的多个传感器的辐射测量装置包括信号处理装置。 信号处理装置在改变光束能量时使用由质子束照射装置产生的信号，并且使得从各个传感器输出的电荷的积累值分别存储在主控制装置中，用于每个能量值。 主控制装置根据存储在主控装置中的积累值计算束能量的深度剂量分布，并表示电荷。 主控制装置根据深度剂量分布计算波束能量的每个值的波束的范围，使用取决于范围的校正系数校正波束能量的深度剂量分布，并且将校正的 深度剂量分布。

公开(公告)号：US20190299027A1

公开(公告)日：2019-10-03

申请号：US16250262

申请日：2019-01-17

Applicant: Hitachi, Ltd.

Inventor： Yusuke FUJII ,  Shinichiro FUJITAKA

IPC: A61N5/10 ,  G16H30/20 ,  G16H20/40

Abstract: A therapy planning apparatus is configured to: discretize an irradiation amount with which a particle beam is irradiated during an irradiation position change for calculation; associate a series of 3D CT images included in a 4D CT image with elapsed time information from start to completion of irradiation of a particle beam; distribute the irradiation amount discretized for the calculation to the 3D CT images based on the 3D CT images and the elapsed time information that are associated; calculate a dose distribution of the particle beam on the 3D CT images to which the irradiation amount is distributed; calculate corresponding positions between the 3D CT images based on non-rigid registration; and integrate a dose distribution formed for each of the 3D CT images during an irradiation period for each of the corresponding positions between the 3D CT images from start to completion of the irradiation of the particle beam.

公开(公告)号：US20180126188A1

公开(公告)日：2018-05-10

申请号：US15805566

申请日：2017-11-07

Applicant: Hitachi, Ltd. ,  NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY

Inventor： Taisuke TAKAYANAGI ,  Toru UMEKAWA ,  Shinichiro FUJITAKA ,  Seishin TAKAO

IPC: A61N5/10

CPC classification number: A61N5/1031 ,  A61N5/1038 ,  A61N2005/1087

Abstract: Provided are a radiation treatment planning system and a radiation treatment system that are capable of achieving time shortening and labor saving of treatment planning making when a radiation treatment is planned. A predicted DVH calculation portion 4034 of an arithmetic processing device 403 in a radiation treatment planning system 400 anisotropically enlarges a target region 501 in an irradiated body image which is input to the radiation treatment planning system 400, and calculates an overlap volume OV with an organ-at-risk region 502 per the number of times of enlargement. A DVH (Dose Volume Histogram) is predicted from a volume of the calculated OV, and a dose histogram in the OV per the number of times of enlargement which is calculated from a past treatment planning data group, and is displayed on a display device 401.

公开(公告)号：US20170216622A1

公开(公告)日：2017-08-03

申请号：US15418838

申请日：2017-01-30

Applicant: Hitachi, Ltd.

Inventor： Shinichiro FUJITAKA ,  Shusuke HIRAYAMA ,  Masumi UMEZAWA

IPC: A61N5/10

CPC classification number: A61N5/103 ,  A61N5/1043 ,  A61N2005/1087

Abstract: A spot determination unit classifies an irradiation region to be irradiated with a charged particle beam into a plurality of layers in an irradiation direction of the charged particle beam, and arranges a plurality of irradiation spots in the plurality of layers. The irradiation spots are classified into groups in accordance with at least either a distance between one irradiation spot and another irradiation spot which are arranged in the same layer or a target irradiation dose of each irradiation spot. A plan is prepared for continuously emitting the charged particle beam while the irradiation position is changed from an irradiation spot belonging to a certain group to a subsequent irradiation spot, and so as to stop emitting the charged particle beam while the irradiation position is changed from an irradiation spot belonging to a certain group to an irradiation spot belonging to another group located in the same layer.