公开(公告)号：US20150056098A1

公开(公告)日：2015-02-26

申请号：US14356962

申请日：2012-12-14

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Toru Inaba ,  Shinya Matsuoka ,  Taku Sakazume ,  Yoshihiro Yamashita ,  Masafumi Shimada

IPC: G01N27/74 ,  G01N33/553

CPC classification number: G01N27/745 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  G01N33/553 ,  G01N2446/00

Abstract: A problem of a sample analysis device that uses magnetic particles is the difficulty in uniformly capturing magnetic particles, specifically the poor uniformity in the vicinity of channel side walls. This causes poor analysis accuracy and reproducibility. The present invention is intended to provide a means to uniformly capture magnetic particles in the vicinity of channel side walls. Specifically, the present invention provides an analysis device that includes a detection channel with an inlet and an outlet through which a sample liquid containing a specific substance and magnetic particles is flowed in and out of the channel, and magnetic field generating means capable of varying the magnitude of the magnetic field in a predetermined region of the detection channel. The width of the magnet in the detector is greater than the channel width. The detector can improve the analysis accuracy and reproducibility of the analysis device.

Abstract translation: 使用磁性颗粒的样品分析装置的问题是难以均匀地捕获磁性颗粒，特别是通道侧壁附近的均匀性差。 这导致分析精度差和重复性差。 本发明旨在提供在通道侧壁附近均匀地捕获磁性颗粒的方法。 具体而言，本发明提供一种分析装置，其具有检测通道，该检测通道具有入口和出口，通过该入口和出口将含有特定物质的样品液体和磁性颗粒流入和流出通道，以及磁场产生装置， 在检测通道的预定区域中的磁场的大小。 检测器中磁体的宽度大于通道宽度。 检测器可以提高分析装置的分析精度和再现性。