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公开(公告)号：US10912890B2
公开(公告)日：2021-02-09
申请号：US16062014
申请日：2016-12-13
Applicant: HOFFMANN-LA ROCHE INC.
Inventor： Maxime Gaillot , Roberta Leah , Declan Reilly , Mark Digby Teucher , Paul Graham Hayton , Jonathan Paul Ridley , James Robert Coop
Abstract: A medical delivery device is disclosed having a rod element with a stem and a first thread arrangement, a dial shell with a second thread arrangement, a delivery orifice, and a switching mechanism. In a dosing status, the rod element is movable relative to the delivery orifice by rotating the dial shell around the stem causing the first thread arrangement and the second thread arrangement to travel along each other, a dosage chamber is formed between the rod element and the delivery orifice when the rod element moves away from the delivery orifice, and the rod element is prevented from movement along a longitudinal axis when an axial force is applied. In a delivery status, the rod element is movable along the longitudinal axis relative to the delivery orifice when an axial force is applied and moving the rod element by rotating the dial shell around the stem is prevented.
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2.发明授权公开(公告)号：US10953161B2
公开(公告)日：2021-03-23
申请号：US16058105
申请日：2018-08-08
Applicant: Hoffmann-La Roche Inc.
Inventor： Sylvain Lanzi , Maxime Gaillot , Rasmus Oehlenschlaeger
IPC: A61M5/32
Abstract: A device for safe and easy removal of a rigid needle shield from a syringe, said device comprising a wall with an inner and an outer surface, the inner surface of the wall defining a tubular hollow portion along the longitudinal axis of the a rigid needle shield, said inner wall comprising a recess adapted to receive a compressible gasket movable within said recess along said longitudinal axis from a portion of the recess wherein said gasket is in a relatively uncompressed state to a portion of said recess wherein said gasket is in a relatively compressed state compared to the relatively uncompressed state, wherein said recess is arranged so that the gasket grips the rigid needle shield in the compressed state.
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公开(公告)号：US11951036B2
公开(公告)日：2024-04-09
申请号：US16760289
申请日：2018-11-02
Applicant: HOFFMANN-LA ROCHE INC.
Inventor： Maxime Gaillot , Roberta Leah , Declan Reilly , Thomas Thueer , Jack Carroll , James Coop , Edward Sims , Mark Teucher
IPC: A61F9/00
CPC classification number: A61F9/0008
Abstract: A device for providing a droplet of a liquid stored in an interior of a vial is disclosed that includes a support body and a resilient dome portion mounted to the support body to form a chamber having air, with the dome portion being configured to create an air flow when activated by compression. The support body includes a vial seat, a nozzle, and air flow and transfer conduits. The support body is arranged, when the vial is received by the vial seat, such that the air flow conduit establishes an air connection between the vial interior and the chamber, the transfer conduit establishes a fluid connection between the vial and the nozzle, and, upon activation of the dome portion, the air flow delivers air into the vial that causes liquid to be transferred from the vial to the nozzle through the transfer conduit.
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公开(公告)号：US11577027B2
公开(公告)日：2023-02-14
申请号：US17258899
申请日：2019-07-09
Applicant: HOFFMANN-LA ROCHE INC.
Inventor： Maxime Gaillot , Alan Dwyer , Pascal Launois , Julian McDonnell , Eoin Connaughton , Mark Digby Teucher , Jonathan Paul Ridley
IPC: A61M5/315
Abstract: A plunger (1) for a medical delivery device comprises: a rod element (2) having a distal end (22) and a proximal end, and a stopper (3) mounted to the rod element (2) at its distal end (22). The rod element (2) has a first form fit structure (24) and the stopper (3) has a second form fit structure (31). The stopper (3) is locked to the rod element (2) by the first form fit structure (24) of the rod element (2) and the second form fit structure (31) of the stopper (3) engaging each other.
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公开(公告)号：US10918795B2
公开(公告)日：2021-02-16
申请号：US16062011
申请日：2016-12-13
Applicant: HOFFMANN-LA ROCHE INC.
Inventor： Maxime Gaillot , Roberta Leah , Declan Reilly , Mark Digby Teucher , Paul Graham Hayton , Jonathan Paul Ridley , James Robert Coop
Abstract: A medical delivery device is disclosed including a rod element, a dosage member and a lock mechanism. The rod element has a stem and the dosage member includes a delivery orifice and a chamber body. The stem of the rod element extends into the chamber body and the delivery orifice is arranged adjacent to a proximal end of the stem. In a dosing status, the rod element is movable along its longitudinal axis relative to the delivery orifice, wherein a dosage chamber is formed within the chamber body between the stem and the delivery orifice such that the dosage chamber increases when the rod element moves away from the delivery orifice. The lock mechanism is adapted to change the medical delivery device from a lock status to a dosing status, wherein, in the lock status moving the rod element along its longitudinal axis relative to the delivery orifice is prevented.
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Patent Agency Ranking
公开(公告)号：US10918793B2
公开(公告)日：2021-02-16
申请号：US16062006
申请日：2016-12-13
Applicant: HOFFMANN-LA ROCHE INC.
Inventor： Maxime Gaillot , Roberta Leah , Declan Reilly , Mark Digby Teucher , Paul Graham Hayton , Jonathan Paul Ridley , James Robert Coop
Abstract: A medical delivery device is disclosed that includes a rod element, a dosage member and a lock mechanism. A stem of the rod element extends into an interior of a chamber body of the dosage member and a delivery orifice of the dosage member is arranged adjacent to a proximal end of the stem of the rod element. In a dosing status, the rod element is movable relative to the delivery orifice of the dosage member, such that a dosage chamber is formed within the chamber body between the stem of the rod element and the delivery orifice, wherein the dosage chamber increases when the rod element moves away from the delivery orifice. The lock mechanism changes the medical delivery device from a lock status to the dosing status, wherein in the lock status the rod element is prevented from moving relative to the dosage member delivery orifice.
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公开(公告)号：US10322859B2
公开(公告)日：2019-06-18
申请号：US15756521
申请日：2016-09-03
Applicant: HOFFMANN-LA ROCHE INC.
Inventor： Maxime Gaillot , Mark Digby Teucher , Daniel Higgins , Andrea Ceccaroni , Oliver Needham , Roberta Leah , Declan Reilly
Abstract: An adapter includes a body piece with an open container end side and a dispenser end side opposite to the container end side, and a collar piece arranged around the body piece. The dispenser end side of the body piece has an orifice. The body piece has a longitudinal axis, a cylindrical outer surface, and a cylindrical inner surface with a container thread oriented towards the container end side. The cylindrical outer surface of the body piece is equipped with a cap thread oriented towards the dispenser end side. The cap thread is arranged to interact with an inner thread of the cap for providing a child resistant closure. A collar piece is connected to the body piece that is freely rotatable relative to the body piece around the longitudinal axis of the body piece. The adapter can be used for efficiently and safely connecting a dispenser to container.
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公开(公告)号：US11951073B2
公开(公告)日：2024-04-09
申请号：US16760514
申请日：2018-11-02
Applicant: HOFFMANN-LA ROCHE INC.
Inventor： Maxime Gaillot , Roberta Leah , Declan Reilly , Thomas Thueer , Jack Carroll , James Coop , Edward Sims , Mark Teucher
CPC classification number: A61J1/2048 , A61J1/1406 , A61J1/2013 , A61J1/2037 , A61J1/2082 , A61J1/2089
Abstract: A device for transferring a liquid from a first vial to a second vial is disclosed having a dome portion configured to create an air flow when activated by compression and re-expansion, and a support body tightly supporting the dome portion to form a chamber with air therein. The support body includes first and second vial seats, and a transfer conduit. The first and second vial seats are arranged to receive the first and second vials. When the first and second vials are received in the first and second vial seats, the transfer conduit is arranged to establish a fluid connection between the first vial and the second vial. Upon activation of the dome portion, air is delivered into the first vial, thereby creating a pressure rise in the first vial which causes the liquid to transfer from the first vial to the second vial through the transfer conduit.
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公开(公告)号：US11529467B2
公开(公告)日：2022-12-20
申请号：US16760198
申请日：2018-11-02
Applicant: HOFFMANN-LA ROCHE INC.
Inventor： Maxime Gaillot , Roberta Leah , Declan Reilly , Paul Hayton , Jonathan Ridley
Abstract: A container adapter for a medical delivery device is disclosed. The medical delivery device has a container seat for holding a container, a dosage chamber, a dosing mechanism and a lock mechanism adapted to prevent operation of the dosing mechanism when no container is held in the container seat and to allow operation of the dosing mechanism when the container is held in the container seat. The container adapter includes an adapter container seat arranged to hold a container, a joint structure arranged to be detachably positioned in the container seat of the medical delivery device and to connect the adapter container seat to the dosing mechanism, and an unlock member adapted to activate the lock mechanism. A delivery assembly and a method of delivering a liquid to a patient from different containers is also disclosed.
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公开(公告)号：US10967129B2
公开(公告)日：2021-04-06
申请号：US16062016
申请日：2016-12-13
Applicant: HOFFMANN-LA ROCHE INC.
Inventor： Maxime Gaillot , Roberta Leah , Declan Reilly , Mark Digby Teucher , Paul Graham Hayton , Jonathan Paul Ridley , James Robert Coop
Abstract: A dosing device includes a rod element and a shell. The rod element has a stem with a longitudinal axis and a first thread arrangement. The shell has a second thread arrangement. The first thread arrangement of the rod element or the second thread arrangement of the shell includes a thread. The first thread arrangement of the rod element and the second thread arrangement of the shell engage. The rod element is movable along the longitudinal axis of its stem by rotating the shell and the rod element relative to each other causing the first thread arrangement of the rod element and the second thread arrangement of the shell to travel along each other. A dosage chamber is formed by moving the rod element along the longitudinal axis of its stem. The volume of the dosage chamber is varied by moving the rod element along the longitudinal axis of its stem. An inclination angle (α, β) of the thread varies along the thread. The dosing device according to the invention can allow for a precise and convenient dosing of a liquid out of a container. In particular, it can allow for efficiently dosing a comparably small volume out of a comparably large container.
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