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    Treatment of elevated histamine and uric acid levels
    1.
    发明授权
    Treatment of elevated histamine and uric acid levels 失效
    治疗组胺升高和尿酸水平升高

    公开(公告)号：US4024253A

    公开(公告)日：1977-05-17

    申请号：US674009

    申请日：1976-04-05

    申请人： Hamao Umezawa ,  Tomio Takeuchi ,  Akira Takamatsu ,  Kenji Kayahara

    发明人： Hamao Umezawa ,  Tomio Takeuchi ,  Akira Takamatsu ,  Kenji Kayahara

    IPC分类号： A61K31/235 ,  A61K31/60 ,  A61K31/22

    CPC分类号： A61K31/235 ,  A61K31/60

    摘要： Compounds having the general formula ##STR1## (the meanings of R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are indicated hereinafter) and the pharmaceutically acceptable salts and esters thereof exhibit strong activities in inhibiting histidine decarboxylase and xanthine oxidase and are useful for treating elevated histamine and uric acid levels. One example is the compound of the formula ##STR2##

    摘要翻译： 具有通式的化合物（R1，R2，R3，R4和R5的含义如下所述），其药学上可接受的盐和酯在抑制组氨酸脱羧酶和黄嘌呤氧化酶中表现出强的活性，并且可用于治疗升高的组胺 和尿酸水平。 一个例子是式“IMAGE”的化合物

    Treatment of elevated histamine and uric acid levels
    3.
    发明授权
    Treatment of elevated histamine and uric acid levels 失效
    治疗组胺升高和尿酸水平升高

    公开(公告)号：US4091097A

    公开(公告)日：1978-05-23

    申请号：US769482

    申请日：1977-02-17

    申请人： Hamao Umezawa ,  Tomio Takeuchi ,  Akira Takamatsu ,  Kenji Kayahara

    发明人： Hamao Umezawa ,  Tomio Takeuchi ,  Akira Takamatsu ,  Kenji Kayahara

    IPC分类号： A61K31/235 ,  A61K31/60

    CPC分类号： A61K31/235 ,  A61K31/60

    摘要： Compounds having the general formula ##STR1## wherein R.sup.2 is substituted either at the 4'-position or at the 5'-position and is hydrogen, fluoro, bromo, chloro, hydroxy or lower alkyl; R.sup.3 is chloro, bromo or lower alkyl; R.sup.4 is hydroxy, amino or lower alkoxy, and Z is hydrogen or lower alkyl and the nontoxic, pharmaceutically acceptable metal salts of said compounds when Z is hydrogen exhibit strong activities in inhibiting histidine decarboxylase and anthine oxidase.

    摘要翻译： 具有通式“IMAGE”的化合物，其中R 2在4位或5位被取代，为氢，氟，溴，氯，羟基或低级烷基; R3是氯，溴或低级烷基; R 4是羟基，氨基或低级烷氧基，Z是氢或低级烷基，当Z是氢时，所述化合物的无毒的药学上可接受的金属盐在抑制组氨酸脱羧酶和蒽氧化酶中表现出强烈的活性。

    Grouting liquid for injection into a ground
    4.
    发明授权
    Grouting liquid for injection into a ground 失效
    注浆液注入地面

    公开(公告)号：US5549419A

    公开(公告)日：1996-08-27

    申请号：US326500

    申请日：1994-10-20

    申请人： Kenji Kayahara

    发明人： Kenji Kayahara

    IPC分类号： E02D3/12 ,  C04B7/14 ,  C04B12/04 ,  C04B28/26 ,  C09K17/02 ,  C09K17/08 ,  C09K17/12 ,  C09K103/00

    CPC分类号： C04B28/26 ,  C09K17/12 ,  C04B2111/00732 ,  C04B2111/70 ,  Y02W30/94

    摘要： A suspension-type grouting liquid for injection into a ground includes sodium aluminate having a mol ratio of 10 or more; and slag, wherein the mol ratio of sodium aluminate is defined as molar concentration of Na.sub.2 O/molar concentration of Al.sub.2 O.sub.3. Preferably, the slag is fine grained and has a specific surface area of 8000 cm.sup.2 /g or more. The grouting liquid may further include at least one additional material selected from the group consisting of cement and dispersant. Preferably the cement is fine grained and has a specific surface area of 8000 cm.sup.2 /g or more. The grouting liquid shows high strength of consolidation in use in spite of having a low viscosity and a long gelation time, and shows a long duration of the strength of consolidation. Another embodiment of the grouting liquid includes water glass having a mol ratio of 2.5 or less; and slag, wherein the mol ratio of the water glass is defined as molar concentration of SiO.sub.2 /molar concentration of Na.sub.2 O, and wherein the slag is fine grained and has a specific surface area of 8000 cm.sup.2 /g or more. Yet another embodiment of the grouting liquid includes water glass; sodium aluminate; and slag, wherein the grouting liquid has a molar concentration of SiO.sub.2 in the water glass/total molar concentration of Na.sub.2 O in the water glass and sodium aluminate of 2.5 or less, and wherein the slag is fine grained and has a specific surface area of 8000 cm.sup.2 /g or more.

    摘要翻译： 用于注射到地下的悬浮型灌浆液包括摩尔比为10以上的铝酸钠; 和渣，其中铝酸钠的摩尔比定义为Na 2 O / Al 2 O 3摩尔浓度的摩尔浓度。 渣优选为细颗粒，比表面积为8000cm2 / g以上。 灌浆液体还可包括至少一种选自水泥和分散剂的附加材料。 优选地，水泥细粒，比表面积为8000cm2 / g以上。 尽管粘度低，凝胶化时间长，但灌浆液的使用强度很高，而且固化强度持续时间长。 灌浆液的另一实施例包括摩尔比为2.5以下的水玻璃; 和渣，其中水玻璃的摩尔比定义为SiO 2 /摩尔浓度的Na 2 O的摩尔浓度，并且其中所述炉渣是细粒的并且具有8000cm 2 / g以上的比表面积。 灌浆液的另一个实施例包括水玻璃; 铝酸钠; 和渣，其中所述灌浆液体在水玻璃中的摩尔浓度为SiO 2 /水玻璃中的Na 2 O的总摩尔浓度为2.5以下，铝酸钠为2.5以下，其中，所述渣为细粒，比表面积为8000 cm2 / g以上。

    Grouting liquid for injection into a ground
    6.
    发明授权
    Grouting liquid for injection into a ground 失效
    注浆液注入地面

    公开(公告)号：US5468292A

    公开(公告)日：1995-11-21

    申请号：US264048

    申请日：1994-06-22

    申请人： Kenji Kayahara ,  Shunsuke Shimada

    发明人： Kenji Kayahara ,  Shunsuke Shimada

    IPC分类号： C04B22/08 ,  C04B28/08 ,  C09K17/02 ,  C09K17/08 ,  C09K103/00 ,  E02D3/12 ,  C04B7/14

    CPC分类号： C04B28/08 ,  C09K17/08 ,  E02D3/12 ,  C04B2111/00732 ,  Y10S106/90

    摘要： A suspension-type grouting liquid for injection into a ground having excellent penetration properties, e.g. low viscosity and long gelation time, and having comparatively high strength after consolidation. The suspension-type grouting liquid for injection into a ground consists essentially of slag, or a combination of slag and cement, alkali metal aluminates, and water. The slag is a fine grain having specific surface area of 5000 cm.sup.2 /g or more, and the alkali metal aluminates have a mole ratio of ({Me.sub.2 O}/{Al.sub.2 O.sub.3 }) of 2.8 or more, in which Me means alkali metal, {Me.sub.2 } and {Al.sub.2 O.sub.3 } represent, respectively, molar concentration of Me.sub.2, and Al.sub.2 O.sub.3.

    摘要翻译： 一种用于注入具有优异渗透特性的地面的悬浮型灌浆液， 粘度低，凝胶化时间长，固结后强度较高。 用于注入地下的悬浮式灌浆液基本上由炉渣或渣和水泥，碱金属铝酸盐和水的组合组成。 渣是比表面积为5000cm2 / g以上的细晶粒，碱金属铝酸盐的摩尔比为（{Me2O} / {Al2O3}）为2.8以上，Me表示碱金属，{ Me2}和{Al2O3}分别表示Me2和Al2O3的摩尔浓度。

    Injection process and injection apparatus for solidifying a ground
    7.
    发明授权
    Injection process and injection apparatus for solidifying a ground 失效
    用于固化地面的注射工艺和注射装置

    公开(公告)号：US4226556A

    公开(公告)日：1980-10-07

    申请号：US942892

    申请日：1978-09-18

    申请人： Kenji Kayahara

    发明人： Kenji Kayahara

    IPC分类号： C09K17/00 ,  C09K17/02 ,  C09K17/06 ,  C09K17/08 ,  C09K17/10 ,  C09K17/12 ,  C09K17/46 ,  C09K17/48 ,  C09K103/00 ,  E02D3/12 ,  E02D3/14

    CPC分类号： C09K17/12 ,  Y10T436/12

    摘要： An injection process for solidifying a soft ground by injecting a blend of water glass type grout thereinto which is a non-alkaline aqueous solution of silicic acid obtained by the mixing water glass into an aqueous solution of acidic reactant so as to remove alkali from the water glass, and an injection apparatus for practicing the injection process which comprises a mixing container for preparing the non-alkaline aqueous solution of silicic acid by adding and mixing the water glass into the aqueous solution of acidic reactant.

    摘要翻译： 通过将水玻璃型浆料的混合物注入其中，通过将水玻璃混合的非碱性硅酸水溶液注入到酸性反应物的水溶液中以从水中除去碱来进行软化处理 玻璃和用于实施注射方法的注射装置，其包括通过将水玻璃加入并混合到酸性反应物的水溶液中来制备非碱性硅酸水溶液的混合容器。