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    Color coated layer-by-layer microcapsules serving as combinatory analysis libraries and as specific optical sensors
    3.
    发明申请
    Color coated layer-by-layer microcapsules serving as combinatory analysis libraries and as specific optical sensors 审中-公开
    作为组合分析库和特定光学传感器的彩色涂层逐层微胶囊

    公开(公告)号：US20060105335A1

    公开(公告)日：2006-05-18

    申请号：US10522998

    申请日：2003-07-29

    申请人： Lars Daehne ,  Barbara Baude ,  Andreas Voigt

    发明人： Lars Daehne ,  Barbara Baude ,  Andreas Voigt

    IPC分类号： C12Q1/68 ,  G01N33/53 ,  C12M1/34 ,  C40B40/10

    CPC分类号： G01N33/587 ,  B01J13/02 ,  B01J13/22 ,  B01J2219/005 ,  B01J2219/00576 ,  C40B99/00

    摘要： Monodisperse colloids were coated with polyelectrolytes using the layer-by-layer method. The template cores can remain in the interior or be dissolved away. Various fluorescent dyes are covalently bonded, in defined quantity, to the polyelectrolytes. The quantity of dye is controlled by varying the label content or by coprecipitating unlabeled polymers. Different. dye layers are separated from each other by intermediate layers, resulting in unwanted interactions being suppressed. Conversely, a FRET signal can be generated between suitable dye pairs at short distances (0-6 nm), with it being possible to control this signal independently of the dye concentration by means of the number of intermediate layers. The capsule coding is read out by varying the excitation and emission wavelengths. Macromolecules which fish out complementary substances from solutions can be immobilized in the capsules. Particles which are coated in this way, or hollow capsules, can be used as sensors after a sensitive intermediate layer has been introduced. Changes in the size/structure of the intermediate layer can be detected either by FRET occurring between adjacent, labeled polyelectrolyte layers or by self-quenching/aggregate fluorescence of dyes in the sensitive layer.

    摘要翻译： 单分散胶体用聚电解质涂覆，使用逐层方法。 模板芯可以保留在内部或溶解掉。 各种荧光染料以规定的量与聚电解质共价键合。 通过改变标签含量或通过共沉淀未标记的聚合物来控制染料的量。 不同。 染料层通过中间层彼此分离，导致不希望的相互作用被抑制。 相反，可以在短距离（0-6nm）的合适的染料对之间产生FRET信号，可以通过中间层的数量独立于染料浓度来控制该信号。 通过改变激发和发射波长来读出胶囊编码。 从溶液中除去互补物质的大分子可以固定在胶囊中。 以这种方式涂覆的颗粒或中空胶囊可以在引入敏感中间层之后用作传感器。 中间层的尺寸/结构的变化可以通过在相邻的标记的聚电解质层之间发生的FRET或通过敏感层中的染料的自猝灭/聚集荧光来检测。

    SMOKE-FREE CIGARETTE, CIGAR OR PIPE
    5.
    发明申请
    SMOKE-FREE CIGARETTE, CIGAR OR PIPE 有权
    无烟无烟香烟，香烟或管子

    公开(公告)号：US20140246033A1

    公开(公告)日：2014-09-04

    申请号：US13985341

    申请日：2012-02-17

    申请人： Lars Daehne ,  Gabriella Egri ,  Heinrich Trescher

    发明人： Lars Daehne ,  Gabriella Egri ,  Heinrich Trescher

    IPC分类号： A24F47/00

    CPC分类号： A24F47/008 ,  A24F47/002 ,  A61M15/0003 ,  A61M15/0028 ,  A61M15/06 ,  A61M16/107 ,  A61M2205/3613

    摘要： The invention relates to a smokeless cigarette, cigar, or pipe having at least one depot (10) for storing and for defined release due to external heat input of nicotine and/or compound comprising nicotine to an airflow to be guided through the depot (10). According to the invention the depot (10) comprises at least one heat transfer segment (16) for targeted heat input for defined release of the nicotine and/or nicotine compound to the airflow.

    摘要翻译： 本发明涉及一种无烟香烟，雪茄或管道，其具有至少一个储存库（10），用于储存和定义的释放，这是由于尼古丁和/或包含尼古丁的化合物的外部热量输入到要引导通过贮存库的气流（10 ）。 根据本发明，贮库（10）包括用于目标热输入的至少一个传热段（16），用于将尼古丁和/或尼古丁化合物定义释放到气流中。