REINFORCED COLLAGEN DEVICE FOR SOFT TISSUE REPAIR

    公开(公告)号:US20220280690A1

    公开(公告)日:2022-09-08

    申请号:US17684196

    申请日:2022-03-01

    摘要: Disclosed herein are embodiments of orthopedic devices. In several embodiments, orthopedic device comprises a biocompatible covering. In several embodiments the biocompatible covering is a collagen-based material. In several embodiments, the collagen-based material is crosslinked using an epoxide-based crosslinking agent (e.g., a diepoxide, triepoxide, etc.). In several embodiments, after a precursor crosslinked collagen-based material is prepared (e.g., by subjecting it to crosslinking conditions), residual crosslinking agent in the precursor material is quenched. In several embodiments, it has been surprisingly found that, by subjecting the precursor crosslinked collagen based material to a quenching reaction (to provide the crosslinked collagen-based material), improved properties are obtained (e.g., lower toxicity lower cytotoxicity, etc.). In several embodiments, the crosslinked collagen-based material is fabricated into an orthopedic device or used to prepare an orthopedic device (e.g., implant).

    PORT-ACCESSIBLE MULTIDIRECTIONAL REINFORCED MINIMALLY INVASIVE COLLAGEN DEVICE FOR SOFT TISSUE REPAIR

    公开(公告)号:US20210338886A1

    公开(公告)日:2021-11-04

    申请号:US17245782

    申请日:2021-04-30

    IPC分类号: A61L27/24 A61F2/08 C08L89/06

    摘要: Disclosed herein are embodiments of a reinforced collagen matrix device for superior capsule repair. The device can include a collagen matrix cover, a first reinforcement strip positioned along the first side of the cover, and a second reinforcement strip positioned along the second side of the cover. A first end and a second end of the first and second reinforcement strips can extend past the first end and the second end of the collagen matrix cover so as not be covered by the collagen matrix cover. The collagen matrix cover can be folded along a first fold and a second fold and extend over the first and second reinforcement strips so that a portion of the first and second reinforcement strips are covered by the collagen matrix cover along a portion of the length of the first reinforcement strip.