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公开(公告)号：US4899500A
公开(公告)日：1990-02-13
申请号：US135855
申请日：1987-12-21
CPC分类号： H01Q1/1242 , E04H12/10 , E04H12/20 , E04H5/02
摘要： A CMR (Cellular Mobile Radiotelephone) Cell Site includes a foundation for a CMR equipment edifice. The foundation, together with the edifice, rests on a leveled surface. An antenna tower is mounted on the roof of the edifice and is secured by an antenna mounting brace embedded in the roof of the edifice. The antenna is guyed at three elevations along the antenna's height to three points on the foundation. The edifice encloses a 10-inch-square, steel support column, positioned within the edifice directly beneath the antenna mounting brace, for supporting the antenna tower. Four-inch-thick slabs of concrete are inserted between the floor of the edifice and the support column and between the support column and the roof so as to isolate the interior of the building from electrical disturbances such as lightening.
摘要翻译： CMR（蜂窝移动无线电话）小区站点包括CMR设备大厦的基础。 基础与大厦一起，位于一个平整的表面上。 天线塔安装在大厦的屋顶上，并通过嵌入大厦屋顶的天线安装支架固定。 天线沿着天线的高度在三个高度被安置在基础上的三个点上。 该大厦包围一个10平方英寸的钢支柱，位于天线安装支架正下方的大厦内，用于支撑天线塔。 4英寸厚的混凝土板被插入在建筑物的地板和支撑柱之间以及支撑柱和屋顶之间，以便隔离建筑物的内部与诸如减轻的电气干扰。
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公开(公告)号：US4951433A
公开(公告)日：1990-08-28
申请号：US135867
申请日：1987-12-21
摘要： A CMR (Cellular Mobile Radiotelephone) Cell Site includes a structurally compact and easily transportable foundation for a CMR equipment edifice. The foundation, together with the edifice, rests on a leveled surface. An antenna tower is mounted on the roof of the edifice and is secured by an antenna mounting brace embedded in the roof of the edifice. The antenna is guyed at three elevations along the antenna's height to three points on the foundation. The edifice encloses a 10-inch-square, steel support column, positioned within the edifice directly beneath the antenna mounting brace, for supporting the antenna tower. Four-inch-thick slabs of concrete are inserted between the floor of the edifice and the support column and between the support column and the roof so as to isolate the interior of the building from electrical disturbances such as lightening.
摘要翻译： CMR（蜂窝移动无线电话）蜂窝站点包括一个结构紧凑且易于运输的CMR设备建筑基础。 基础与大厦一起，位于一个平整的表面上。 天线塔安装在大厦的屋顶上，并通过嵌入大厦屋顶的天线安装支架固定。 天线沿着天线的高度在三个高度被安置在基础上的三个点上。 该大厦包围一个10平方英寸的钢支柱，位于天线安装支架正下方的大厦内，用于支撑天线塔。 4英寸厚的混凝土板被插入在建筑物的地板和支撑柱之间以及支撑柱和屋顶之间，以便隔离建筑物的内部与诸如减轻的电气干扰。
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公开(公告)号：US4912893A
公开(公告)日：1990-04-03
申请号：US135871
申请日：1987-12-21
CPC分类号： E04H12/2238 , E04H12/20 , H01Q1/1235
摘要： CMR (Cellular Mobile Radiotelephone) equipment is disposed in a configuration that facilitates both transportation to a cell site and, at the site, rapid installation of the CMR equipment and accompanying antenna tower. The CMR equipment incorporates a foundation that includes (i) a rectangular center structure formed from a front horizontal section, a rear horizontal section, a left vertical section, and a right vertical section, and (ii) a nose structure attached to and extending vertically from the front horizontal section. A self-contained CMR equipment edifice, having four walls, a floor and a roof, is secured to the rectangular center structure of the foundation by a plurality of flanges positioned at predetermined locations on the edifice and affixed to both the foundation and walls of the edifice. Several antenna tower sections are attached to the edifice by a number of identical antenna mounting assemblies. Each of the antenna mounting assemblies comprises a bracket attached to a wall of the edifice and a pipe strap removably affixed to the bracket. Left and right crossmember sections are attached to walls of the edifice by the above-mentioned flanges. The left and right crossmember sections are, in turn, respectively secured to top plates of the left vertical and right vertical sections, thereby securing the edifice to the foundation. Left and right leg sections, pivotably attached to opposite ends of the rear horizontal section, are folded into proximity with, respectively, the left vertical section and the right vertical section. In a preferred embodiment, the rear horizontal section includes a left bracket plate pair, disposed at the left end of the rear horizontal section, for accommodating the pivotable attachment of the left leg section. A right bracket plate pair is similarly disposed at a right end for the right leg section.
摘要翻译： CMR（蜂窝移动无线电话）设备被布置成便于运输到小区站点，并且在现场快速安装CMR设备和伴随的天线塔。 CMR设备包括一个基础，其包括（i）由前水平部分，后水平部分，左垂直部分和右垂直部分形成的矩形中心结构，以及（ii）连接并垂直延伸的鼻部结构 从前面的水平部分。 具有四个墙壁，地板和屋顶的独立的CMR设备建筑物通过位于大厦的预定位置处的多个法兰固定到基座的矩形中心结构，并且固定到基座和墙壁上 大厦。 几个天线塔段通过多个相同的天线安装组件连接到建筑物。 每个天线安装组件包括附接到建筑物的壁的支架和可拆卸地固定到支架的管带。 左右交叉部分通过上述法兰连接到大厦的墙壁。 左和右横梁部分又分别固定在左垂直和右垂直部分的顶板上，从而将大楼固定在基础上。 可枢转地附接到后水平部分的相对端的左腿部分和右腿部分别分别折叠成左垂直部分和右垂直部分。 在优选实施例中，后水平部分包括设置在后水平部分的左端的左托架板对，用于容纳左腿部分的可枢转附件。 右支架板对同样地设置在右腿部分的右端。
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公开(公告)号：US11219680B2
公开(公告)日：2022-01-11
申请号：US16487621
申请日：2018-02-20
申请人： Merck Sharp & Dohme Corp. , John E. MacNair , Michael A. Winters , Thomas Svab , Sheng-Ching Wang , William J. Smith , Cecilia Giovarelli
发明人： John E. MacNair , Michael A. Winters , Thomas Svab , Sheng-Ching Wang , William J. Smith , Cecilia Giovarelli
摘要： The present invention provides immunogenic compositions having one or more polysaccharide-protein conjugates in which polysaccharides obtained from bacterial capsules are conjugated to diphtheria toxin fragment B (DTFB) or a variant thereof. The immunogenic compositions may be multivalent pneumococcal polysaccharide conjugate compositions in which polysaccharides from one or more Steptococcus pneumoniae serotypes are conjugated to diphtheria toxin fragment B (DTFB) and, optionally, additional polysaccharides from one or more different Steptococcus pneumoniae serotypes are conjugated to one or more other carrier proteins.
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5.发明授权公开(公告)号：US10933244B2
公开(公告)日：2021-03-02
申请号：US15860117
申请日：2018-01-02
摘要： An apparatus, system and technique selectively eliminates the noxious signal components in a neuronal signal by creating an interfering electrical signal that is tuned to a given frequency corresponding to the oscillatory pattern of the noxious signal, resulting in a modified neuronal signal that substantially reproduces a normal, no-pain neuronal signal. The disclosed system and technique of pain relief is based on the hypothesis that the temporal profile of pain signals encodes particular components that oscillate at unique and quantifiable frequencies, which are responsible for pain processing in the brain.
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6.发明申请公开(公告)号：US20180185645A1
公开(公告)日：2018-07-05
申请号：US15860117
申请日：2018-01-02
CPC分类号： A61N1/36071 , A61B5/04001 , A61B5/04017 , A61B5/048 , A61B5/4047 , A61B5/4824 , A61B5/4836 , A61N1/0556 , A61N1/36139 , A61N1/36171 , A61N1/37264
摘要： An apparatus, system and technique selectively eliminates the noxious signal components in a neuronal signal by creating an interfering electrical signal that is tuned to a given frequency corresponding to the oscillatory pattern of the noxious signal, resulting in a modified neuronal signal that substantially reproduces a normal, no-pain neuronal signal. The disclosed system and technique of pain relief is based on the hypothesis that the temporal profile of pain signals encodes particular components that oscillate at unique and quantifiable frequencies, which are responsible for pain processing in the brain.
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公开(公告)号：US20200054740A1
公开(公告)日：2020-02-20
申请号：US16487610
申请日：2018-02-20
IPC分类号： A61K39/385 , A61K47/10 , A61K47/20 , A61K47/26 , A61K47/36 , C07K1/107 , C07K14/315
摘要： The present invention provides pneumococcal conjugate vaccine formulations comprising surfactant systems incorporating polysorbate 20 or a combination of a poloxamer and a polyol.
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8.发明申请NOVEL FORMULATIONS WHICH MITIGATE AGITATION-INDUCED AGGREGATION OF IMMUNOGENIC COMPOSITIONS 审中-公开缓解激素诱导的免疫组化聚集的新型配方公开(公告)号：US20130273098A1
公开(公告)日：2013-10-17
申请号：US13992844
申请日：2011-12-05
IPC分类号： A61K39/385
CPC分类号： A61K39/385 , A61K33/06 , A61K47/6415 , A61K47/646 , A61K2300/00
摘要： The present invention provides novel formulations which mitigate agitation-induced aggregation of immunogenic compositions particularly those having polysaccharide-protein conjugates. Specifically, the novel formulations comprise a poloxamer within a molecular weight range of 1100 to 17,400 which provides significant advantages over previously used surfactants including polysorbate 80. In one embodiment, the present invention provides a multivalent immunogenic composition having 15 distinct polysaccharide-protein conjugates and a poloxamer. Each conjugate consists of a capsular polysaccharide prepared from a different serotype of Streptococcus pneumoniae (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, 22F, 23F or 33F) conjugated to a carrier protein, preferably CRM197.
摘要翻译： 本发明提供了减轻免疫原性组合物的搅动诱导聚集的新型制剂，特别是那些具有多糖 - 蛋白质共轭物的组合物。 具体地说，新型制剂包含分子量范围为1100至17,400的泊洛沙姆，其比先前使用的表面活性剂包括聚山梨醇酯80提供了显着的优点。在一个实施方案中，本发明提供具有15种不同多糖 - 蛋白质缀合物的多价免疫原性组合物和 泊洛沙姆 每个缀合物由与载体结合的不同血清型肺炎链球菌（1,3,4,5,6A，6B，7F，9V，14,18C，19A，19F，22F，23F或33F）制备的荚膜多糖组成。 蛋白质，优选CRM197。
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公开(公告)号：US4893131A
公开(公告)日：1990-01-09
申请号：US206806
申请日：1988-06-15
申请人： William J. Smith , Jack M. Smith
发明人： William J. Smith , Jack M. Smith
CPC分类号： H01Q9/30 , H01Q1/3275
摘要： A transmitting and receiving radio frequency antenna of arcuate shape, serving as a radio frequency radiator of wave lengths between about 2 meters to about 160 meters. A tuning and loading coil is connected to one end of said antenna for tuning and matching said arcuate radiator. A capacitance is connected at the other, coupling to ground. Advantage of vertical and horizontal polarization is obtained.
摘要翻译： 一种弧形发射和接收射频天线，用作波长约2米至约160米的射频辐射器。 调谐和加载线圈连接到所述天线的一端，用于调谐和匹配所述弧形散热器。 另一端连接电容，接地。 获得垂直和水平极化的优点。
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公开(公告)号：US4786047A
公开(公告)日：1988-11-22
申请号：US903403
申请日：1986-09-02
CPC分类号： B65H29/20 , B65H2701/1912
摘要： Apparatus for conveying a sheet of paper from a power feeder to an exit point including a frame for guiding the moving sheet along a preselected path and including a flexible member between the feeder and the exit point for normally guiding the sheet along the preselected path, the flexible member allowing the sheet to buckle in a direction normal to the plane of and away from the preselected path in response to an obstruction.
摘要翻译： 用于将一张纸从供电器输送到出口点的设备，该出口点包括用于沿着预选路径引导移动片材的框架，并且在馈送器和出口点之间包括柔性构件，用于沿预选路径正常引导片材， 柔性构件允许片材响应于障碍物沿垂直于预定路径的平面并远离预选路径的方向弯曲。
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